Hematology Research Seminars

2012-2013

Friday, 4:00 PM, Room 8841 CSRB (except as noted)

 
Date Speaker/Title
September 14, 2012 Eline van Meel (Stuart Kornfeld)
Work-in-progress: “Mannose 6-Phosphate Independent Lysosomal Targeting of Acid alpha-Glucosidase”
  Cara Lunn (Matt Walter)
Work-in-progress: “U2AF1 Splicing Factor Mutations in Myelodysplastic Syndromes”
September 21, 2012 Monita P. Wilson, Ph.D.
Hematology Division
“ITPK1: an Inositol Kinase Linked to Neural Tube Defects”
September 28, 2012 Ryan Sullivan (Todd Fehniger)
Work-in-progress: “The Role of miR-155 in Natural Killer Cell Function”
  Jing Huang (Evan Sadler)
Work-in-progress: “Distinct Functions of pH-Sensing Histidine Residues in the Multimer Assembly and Storage of von Willebrand Factor in Weibel-Palade Bodies”
October 5, 2012 John S. Welch, M.D., Ph.D.
Oncology Division, Stem Cell Biology Section
“The Origin and Evolution of AML Mutations”
October 12, 2012 Angela Verdoni (Tim Ley)
Work-in-progress: “Understanding the Role of DNMT3A Mutations in AML Pathogenesis”
  Ren-Huai Huang (Evan Sadler)
Work-in-progress: “How Von Willebrand Factor is Condensed into Weibel-Palade Bodies”
October 18, 2012 Roger J. S. Preston, Ph.D.
Department of Haematology, Trinity College Dublin, Ireland
“Regulating the Regulator: Modulating Activated Protein C Functions for Therapeutic Gain”
October 19, 2012 Daniel C. Link, M.D.
Oncology Division, Stem Cell Biology Section
“Characterizing the Stem Cell Niche”
October 26, 2012 Monica Qian (Stuart Kornfeld)
Work-in-progress: “Missense Mutations in Mucolipidosis II and Mucolipidosis III”
  Daniel Fisher (Stephen Oh)
Work-in-progress: “Genomic Study of Myeloproliferative Neoplasia”
November 2, 2012 5th Rosalind Kornfeld Lecture
Susan R. Wente, Ph.D.
Vanderbilt University
“Beyond the Pore: From Nuclear mRNA Export to Translation”
November 9, 2012 40th Carl Moore Lecture
Gerald R. Crabtree, M.D.
HHMI/Stanford University
“Chromatin Regulation: New Methods and Concepts”
November 16, 2012 Tom Girard (George Broze)
Work-in-progress: “Protein Z, Protein Z-Dependent Protease Inhibitor (SerpinA10) and the Acute Phase Response”
  Dhanam Anbukumar (Evan Sadler)
Work-in-progress: “Characterizing VWF Propeptide Ca2+ Binding Sites”
December 14, 2012 Daniel E. Goldberg, M.D., Ph.D.
Infectious Diseases Division
“Trial by Fire and Famine: How the Malaria Parasite Survives in its Host Erythrocyte”
January 3, 2013 Rong Lu, Ph.D.
Institute for Stem Cell Biology and Regenerative Medicine, Stanford University
“Systems Analysis of Mouse Hematopoietic Stem Cells in Vivo at the Single Cell Level”
January 11, 2013 Balraj Doray (Stuart Kornfeld)
Work-in-progress: “Gga2 Knockout Mice Revisited”
  Joshua Muia (Evan Sadler)
Work-in-progress: “pH Dependent Activity of ADAMTS13 and Self-regulatory Mechanisms”
January 15, 2013 Jongseong Kim, Ph.D.
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
“Single-molecule Mechanobiology of Von Willebrand Factor (VWF) to Arbitrate Between Bleeding, Hemostasis, and Thrombosis”
January 18, 2013 J. Evan Sadler, M.D., Ph.D.
Hematology Division
“Assembly and Destruction of von Willebrand Factor”
January 25, 2013 Sarah Amend (Kathy Weilbaecher)
Work-in-progress: “Of Mice and Men: Genetic Contributions of Susceptibility to MGUS, the Requisite Precursor of Multiple Myeloma”
  Terrence Wong (Dan Link)
Work-in-progress: “The Genetics of Therapy-related AML”
February 1, 2013 Stuart Kornfeld, M.D.
Hematology Division
“New Insights into the Man-6-P Lysosomal Targeting Pathway Through Analysis of Mutations in I-cell Disease and Pseudo-Hurler Polydystrophy”
February 7, 2013 Eirini Trompouki, Ph.D.
Division of Hematology Oncology, Children’s Hospital Boston
“From Zebrafish to Man: BMP and Wnt Signaling Pathways in Normal and Stress Hematopoiesis”
February 8, 2013 Adam Searleman (Ron Bose)
Work-in-progress: “Mechanisms of Transformation in HER2-Overexpressing Mammary Epithelium”
  Kristin Sanfilippo (Ken Carson)
Work-in-progress: “Thrombosis in Myeloma”
February 14, 2013 Dhvanit I. Shah, Ph.D.
Division of Hematology, Brigham and Women’s Hospital, Boston
“Genetic Screen to Identify Genes Regulating Hematopoiesis”
February 15, 2013 George J. Broze Jr., M.D.
Hematology Division
“Translational Studies of Tissue Factor Inhibitors”
February 22, 2013 Leili Dolatshahi (Evan Sadler)
Work-in-progress: “Adjuvant Low Dose Rituximab for Patients with TTP”
  Meagan Jacoby (Matt Walter)
Work-in-progress: “Dysfunctional Double Strand Break Repair in Therapy-related AML”
March 1, 2013 Garima Gupta (Evan Sadler)
Work-in-progress: “Non-catalytic Interaction Between VWF and ADAMTS-13”
  Mathew Cherian (Lee Ratner)
Work-in-progress: “Role of PI3K-Akt-mTOR in HTLV-Tax Induced Transformation”
March 8, 2013 Katherine N. Weilbaecher, M.D.
Oncology Division, Molecular Oncology Section
“Targeting Beta3 Integrin Pathway Genes to Treat Cancer”
March 15, 2013 David B. Wilson, M.D., Ph.D.
Division of Hematology/Oncology, Department of Pediatrics
“Adrenocortical Development and Tumorigenesis: the Saga of Rosie”
March 21, 2013 Luis F. Z. Batista, Ph.D.
Department of Medicine/Hematology, Stanford University
“Human iPS Cells as a Model to Study Telomere Dysfunction-induced Disease”
March 22, 2013 Christopher Cole (Tim Ley)
Work-in-progress: “Role of DNMT3A in Acute Promyelocytic Leukemia”
  Jian Zhu (Evan Sadler)
Work-in-progress: “Regulation of ADAMTS13 Activity”
March 29, 2013 Stephen T. Oh, M.D., Ph.D.
Hematology Division
“Towards an Understanding of Genetic and Phenotypic Complexity in Myeloproliferative Neoplasms”
April 5, 2013 Maria Trissal (Dan Link)
Work-in-progress: “Dysregulation of the Imprinted DLK1-DIO3 Locus in Promyelocytic Leukemia”
  Wang-Sik Lee (Stuart Kornfeld)
Work-in-progress: “Structure and Function of the DUF2233 Domain in Bacteria and in Human UCE”
April 11, 2013 Christopher M. Sturgeon, Ph.D.
McEwen Centre for Regenerative Medicine, Toronto
“Modeling Developmental Hematopoiesis Using Pluripotent Stem Cells”
April 12, 2013 Katherine P. Ponder, M.D.
Hematology Division
“The Effect of Gene Therapy for Mucopolysaccharidosis After a Decade”
April 19, 2013 Rachel Idol (Stuart Kornfeld)
Work-in-progress: “CNS Defects in Mice Lacking Mannose-6-Phosphate”
April 26, 2013 Anna M. Randi, Ph.D.
National Heart & Lung Institute, Imperial College London
“Von Willebrand Factor Regulates Angiogenesis and Endothelial Progenitors’ Function”
May 3, 2013 Betsy Engle (Stephen Oh)
Work-in-progress: “Genetic Complexity and Clonal Evolution in Myeloproliferative Neoplasms”
  Timothy Collier (Ron Bose)
Work-in-progress: “Probing the Structure and Dimerization of EGFR Family Tyrosine Kinases”
May 10, 2013 Michael H. Tomasson, M.D.
Oncology Division, Molecular Oncology Section
“The Role of Orphan snoRNA ACA11 in the Pathogenesis of t(4;14)-positive Multiple Myeloma”