Leonard B. Maggi, Jr., Ph.D.

Publications

• Maggi LB Jr, Weber JD
  Forget transcription: translation is where the action is.
  Mol Cell Biol 2013 May;33(10):1884-5
• Chu L, Su MY, Maggi LB Jr, Lu L, Mullins C, Crosby S, Huang G, Chng WJ, Vij R, Tomasson MH
  Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.
  J Clin Invest 2012 Aug 1;122(8):2793-806
• Winkeler CL, Kladney RD, Maggi LB Jr, Weber JD
  Cathepsin k-cre causes unexpected germline deletion of genes in mice.
  PLoS One 2012;7(7):e42005
• Brady SN, Maggi LB Jr, Winkeler CL, Toso EA, Gwinn AS, Pelletier CL, Weber JD
  Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation.
  Oncogene 2009 Sep 10;28(36):3209-20
• Vanderwaal RP, Maggi LB Jr, Weber JD, Hunt CR, Roti Roti JL
  Nucleophosmin redistribution following heat shock: a role in heat-induced radiosensitization.
  Cancer Res 2009 Aug 15;69(16):6454-62
• Maggi LB Jr, Kuchenruether M, Dadey DY, Schwope RM, Grisendi S, Townsend RR, Pandolfi PP, Weber JD
  Nucleophosmin serves as a rate-limiting nuclear export chaperone for the mammalian ribosome.
  Mol Cell Biol 2008 Dec;28(23):7050-65
• Apicelli AJ, Maggi LB Jr, Hirbe AC, Miceli AP, Olanich ME, Schulte-Winkeler CL, Saporita AJ, Kuchenreuther M, Sanchez J, Weilbaecher K, Weber JD
  A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function.
  Mol Cell Biol 2008 Feb;28(3):1068-80
• Pelletier CL, Maggi LB Jr, Brady SN, Scheidenhelm DK, Gutmann DH, Weber JD
  TSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translation.
  Cancer Res 2007 Feb 15;67(4):1609-17
• Steer SA, Moran JM, Christmann BS, Maggi LB Jr, Corbett JA
  Role of MAPK in the regulation of double-stranded RNA- and encephalomyocarditis virus-induced cyclooxygenase-2 expression by macrophages.
  J Immunol 2006 Sep 1;177(5):3413-20
• Yu Y, Maggi LB Jr, Brady SN, Apicelli AJ, Dai MS, Lu H, Weber JD
  Nucleophosmin is essential for ribosomal protein L5 nuclear export.
  Mol Cell Biol 2006 May;26(10):3798-809
• Khor B, Bredemeyer AL, Huang CY, Turnbull IR, Evans R, Maggi LB Jr, White JM, Walker LM, Carnes K, Hess RA, Sleckman BP
  Proteasome activator PA200 is required for normal spermatogenesis.
  Mol Cell Biol 2006 Apr;26(8):2999-3007
• Brady SN, Yu Y, Maggi LB Jr, Weber JD
  ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway.
  Mol Cell Biol 2004 Nov;24(21):9327-38
• Maggi LB Jr, Moran JM, Buller RM, Corbett JA
  ERK activation is required for double-stranded RNA- and virus-induced interleukin-1 expression by macrophages.
  J Biol Chem 2003 May 9;278(19):16683-9
• Steer SA, Moran JM, Maggi LB Jr, Buller RM, Perlman H, Corbett JA
  Regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded RNA and viral infection.
  J Immunol 2003 Jan 15;170(2):1070-6
• Maggi LB Jr, Moran JM, Scarim AL, Ford DA, Yoon JW, McHowat J, Buller RM, Corbett JA
  Novel role for calcium-independent phospholipase A(2) in the macrophage antiviral response of inducible nitric-oxide synthase expression.
  J Biol Chem 2002 Oct 11;277(41):38449-55
• Blair LA, Maggi LB Jr, Scarim AL, Corbett JA
  Role of interferon regulatory factor-1 in double-stranded RNA-induced iNOS expression by mouse islets.
  J Biol Chem 2002 Jan 4;277(1):359-65
• Blair LA, Heitmeier MR, Scarim AL, Maggi LB Jr, Corbett JA
  Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets.
  Diabetes 2001 Feb;50(2):283-90
• International Human Genome Sequencing Consortium
  Initial sequencing and analysis of the human genome.
  Nature 2001 Feb 15;409(6822):860-921
• Maggi LB Jr, Heitmeier MR, Scheuner D, Kaufman RJ, Buller RM, Corbett JA
  Potential role of PKR in double-stranded RNA-induced macrophage activation.
  EMBO J 2000 Jul 17;19(14):3630-8
• Maggi LB Jr, Sadeghi H, Weigand C, Scarim AL, Heitmeier MR, Corbett JA
  Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression.
  Diabetes 2000 Mar;49(3):346-55
• The C. elegans Sequencing Consortium
  Genome sequence of the nematode C. elegans: a platform for investigating biology.
  Science 1998 Dec 11;282(5396):2012-8