WASHINGTON UNIVERSITY SCHOOL OF MEDICINE DEPARTMENT OF MEDICINE

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The emphasis of the hematology clinic, where I see the majority of outpatients, is on the diagnosis and treatment of disorders of the red blood cells as well as platelet and coagulation abnormalities. Although initially organized as a consultative clinic, providing hematologic diagnosis and management recommendations to other healthcare providers, many patients with hematologic diseases receive long-term care in this setting. In the 1993-94 academic year there were over 400 clinic visits including approximately 130 new patients. The clinic has recently expanded to three one-half day clinics to accommodate an increase in patient visits.

There are several areas of clinical research that I am pursuing. In collaboration with members of the Division of Laboratory Medicine, I plan to develop alternative assays to aid in the management of anticoagulant dosing for patients with thromboembolic disease.

The area in which we provide the most long-term care is the integrated management of patients with sickle cell disease and related hemoglobinopathies. I am in the process of evaluating several aspects of their care such as dental disease and the use of indwelling venous catheters.

I also am developing a library to store plasma and DNA samples from patients with hematologic diseases. This will allow for the potential identification of specific mutations and may provide insight in the long run into new diagnostic assays.

Factor VIII activity and inhibitor in a patient treated with Rituximab CVP: cyclophosphamide, vincristine and prednisone PO CTX: oral cyclophosphamide

From: Field JJ, Fenske TS, Blinder MA Rituximab for the treatment of patients with very high-titre acquired factor VIII inhibitors refractory to conventional chemotherapy. Haemophilia 2007 Jan;13(1):46-50

Education

1973-1977	BS, University of Notre Dame, Notre Dame, IN
1977-1981	MD, St. Louis University School of Medicine, St. Louis, MO

Post-graduate Training

1981-1984	Resident in Internal Medicine, Department of Medicine, University of Illinois School of Medicine, Chicago, IL
1984-1986	Fellow in Hematology, Department of Internal Medicine, University of Washington School of Medicine, Seattle, WA
1986-1990	Post-doctoral Research Fellow, Division of Hematology-Oncology, Washington University School of Medicine, St. Louis, MO

Academic Positions

1990-1998	Assistant Professor, Division of Laboratory Medicine, Washington University School of Medicine, St. Louis, MO
1994-present	Medical Director, Wohl Hematology Laboratory
1996-present	Associate Member, Alvin J. Siteman Cancer Center
1998-present	Associate Professor of Medicine and Pathology, Washington University School of Medicine, St. Louis, MO

Professional Societies

1991	American Federation of Clinical Research
1991	American Society for Biochemistry and Molecular Biology
1992	American Society of Hematology
1993	American College of Physicians, Member
1995	Academy of Clinical Laboratory Physicians and Scientists

Board Certification

1984	Diplomate of the American Board of Internal Medicine
1987	Diplomate of the American Board in Medical Oncology
1988	Diplomate of the American Board in Hematology

Honors & Awards

1987-1989	Fellow of the American Heart Association, Missouri Affiliate
1990	European Patent Number 90870188.1; "Modified Heparin Cofactor  II;" Inventors: DM Tollefsen, VM Derechin, MA Blinder
1992	U.S. Patent Number 5,102,995; "DNA Encoding Modified Heparin Cofactor II;" Inventors: DM Tollefsen, VM Derechin, MA Blinder
1992	U.S. Patent Number 5,118,793; "Modified Heparin Cofactor II;" Inventors: DM Tollefsen, VM Derechin, and MA Blinder
1995	Outstanding Teacher for the 1994-95 Academic Year, Department of Internal Medicine, Washington University School of Medicine
1999	Dr. Neville Grant Award for Clinical Excellence
2001-2006	Listed in Best Doctors in America
2001-2006	Listed in Castle Connolly America's Top Doctors
2004-2006	Missouri Genetic Disease Advisory Committee, Appointed by Governor Bob Holden
2005-2007	Vice Chair of the Executive Committee of the Faculty Council, Washington University School of Medicine

Updated: March 20, 2008