George J. Broze, Jr., M.D.

Ndonwi M, Broze G Jr
Protein S enhances the tissue factor pathway inhibitor inhibition of factor Xa but not its inhibition of factor VIIa-tissue factor.
J Thromb Haemost 2008 Jun;6(6):1044-6

Zhang J, Tu Y, Lu L, Lasky N, Broze GJ Jr
Protein Z-dependent protease inhibitor deficiency produces a more severe murine phenotype than protein Z deficiency.
Blood 2008 May 15;111(10):4973-8

Milsom C, Yu J, May L, Meehan B, Magnus N, Al-Nedawi K, Luyendyk J, Weitz J, Klement P, Broze GJ Jr, Mackman N, Rak J
The role of tumor- and host-related tissue factor pools in oncogene-driven tumor progression.
Thromb Res 2007;120(Suppl 2):S82-91

Ndonwi M, Broze GJ Jr, Agah S, Schmidt AE, Bajaj SP
Substitution of the Gla domain in factor X with that of protein C impairs its interaction with factor VIIa/tissue factor: lack of comparable effect by similar substitution in factor IX.
J Biol Chem 2007 May 25;282(21):15632-44

Fujimoto H, Gabazza EC, Taguchi O, Nishii Y, Nakahara H, Bruno NE, D'Alessandro-Gabazza CN, Kasper M, Yano Y, Nagashima M, Morser J, Broze GJ, Suzuki K, Adachi Y
Thrombin-activatable fibrinolysis inhibitor deficiency attenuates bleomycin-induced lung fibrosis.
Am J Pathol 2006 Apr;168(4):1086-96

Refaai MA, Ahn C, Lu L, Wu K, Broze GJ Jr
Protein Z and ZPI levels and cardiovascular events.
J Thromb Haemost 2006 Jul;4(7):1628-9

Liu T, Scallan CD, Broze GJ Jr, Patarroyo-White S, Pierce GF, Johnson KW
Improved coagulation in bleeding disorders by Non-Anticoagulant Sulfated Polysaccharides (NASP).
Thromb Haemost 2006 Jan;95(1):68-76

Piro O, Broze GJ Jr
Comparison of cell-surface TFPIalpha and beta.
J Thromb Haemost 2005 Dec;3(12):2677-83

Martinuzzo M, Iglesias Varela ML, Adamczuk Y, Broze GJ, Forastiero R
Antiphospholipid antibodies and antibodies to tissue factor pathway inhibitor in women with implantation failures or early and late pregnancy losses.
J Thromb Haemost 2005 Nov;3(11):2587-9

Al-Shanqeeti A, van Hylckama Vlieg A, Berntorp E, Rosendaal FR, Broze GJ Jr
Protein Z and protein Z-dependent protease inhibitor. Determinants of levels and risk of venous thrombosis.
Thromb Haemost 2005 Mar;93(3):411-3

Ndonwi M, Broze G Jr, Bajaj SP
The first epidermal growth factor-like domains of factor Xa and factor IXa are important for the activation of the factor VII--tissue factor complex.
J Thromb Haemost 2005 Jan;3(1):112-8

Piro O, Broze GJ Jr
Role for the Kunitz-3 domain of tissue factor pathway inhibitor-alpha in cell surface binding.
Circulation 2004 Dec 7;110(23):3567-72

Lu G, Broze GJ Jr, Krishnaswamy S
Formation of factors IXa and Xa by the extrinsic pathway: differential regulation by tissue factor pathway inhibitor and antithrombin III.
J Biol Chem 2004 Apr 23;279(17):17241-9

Vossen CY, Hasstedt SJ, Rosendaal FR, Callas PW, Bauer KA, Broze GJ, Hoogendoorn H, Long GL, Scott BT, Bovill EG
Heritability of plasma concentrations of clotting factors and measures of a prethrombotic state in a protein C-deficient family.
J Thromb Haemost 2004 Feb;2(2):242-7

Forastiero RR, Martinuzzo ME, De Larranaga G, Broze GJ
Antibodies to tissue factor pathway inhibitor are uncommonly detected in patients with infection-related antiphospholipid antibodies.
J Thromb Haemost 2003 Oct;1(10):2250-1

Forastiero RR, Martinuzzo ME, Lu L, Broze GJ
Autoimmune antiphospholipid antibodies impair the inhibition of activated factor X by protein Z/protein Z-dependent protease inhibitor.
J Thromb Haemost 2003 Aug;1(8):1764-70

Broze GJ Jr
The rediscovery and isolation of TFPI.
J Thromb Haemost 2003 Aug;1(8):1671-5

Zhang J, Piro O, Lu L, Broze GJ Jr
Glycosyl phosphatidylinositol anchorage of tissue factor pathway inhibitor.
Circulation 2003 Aug 5;108(5):623-7

Forastiero RR, Martinuzzo ME, Broze GJ
High titers of autoantibodies to tissue factor pathway inhibitor are associated with the antiphospholipid syndrome.
J Thromb Haemost 2003 Apr;1(4):718-24

Zhang J, Broze G
Fg12 prothrombinase activity?
Thromb Haemost 2002 Nov;88(5):872-4

Nagashima M, Yin ZF, Broze GJ Jr, Morser J
Thrombin-activatable fibrinolysis inhibitor (TAFI) deficient mice.
Front Biosci 2002 Feb 1;7:d556-68

Nagashima M, Yin ZF, Zhao L, White K, Zhu Y, Lasky N, Halks-Miller M, Broze GJ Jr, Fay WP, Morser J
Thrombin-activatable fibrinolysis inhibitor (TAFI) deficiency is compatible with murine life.
J Clin Invest 2002 Jan;109(1):101-10

Eitzman DT, Westrick RJ, Bi X, Manning SL, Wilkinson JE, Broze GJ, Ginsburg D
Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden.
Circulation 2002 May 7;105(18):2139-42

Caplice NM, Panetta C, Peterson TE, Kleppe LS, Mueske CS, Kostner GM, Broze GJ Jr, Simari RD
Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis.
Blood 2001 Nov 15;98(10):2980-2987

Westrick RJ, Bodary PF, Xu Z, Shen YC, Broze GJ, Eitzman DT
Deficiency of tissue factor pathway inhibitor promotes atherosclerosis and thrombosis in mice.
Circulation 2001 Jun 26;103(25):3044-6

Broze GJ Jr
Protein Z-dependent regulation of coagulation.
Thromb Haemost 2001 Jul;86(1):8-13

Zhang J, Broze GJ Jr
Mouse protein Z-dependent protease inhibitor cDNA.
Thromb Haemost 2001 May;85(5):861-5

Broze GJ Jr, Yin ZF, Lasky N
A tail vein bleeding time model and delayed bleeding in hemophiliac mice.
Thromb Haemost 2001 Apr;85(4):747-8

Tabatabai A, Fiehler R, Broze GJ Jr
Protein Z circulates in plasma in a complex with protein Z-dependent protease inhibitor.
Thromb Haemost 2001 Apr;85(4):655-60

Broze GJ Jr
Protein-Z and thrombosis.
Lancet 2001 Mar 24;357(9260):900-1

Han X, Fiehler R, Broze GJ Jr
Characterization of the protein Z-dependent protease inhibitor.
Blood 2000 Nov 1;96(9):3049-55

Yin ZF, Huang ZF, Cui J, Fiehler R, Lasky N, Ginsburg D, Broze GJ Jr
Prothrombotic phenotype of protein Z deficiency.
Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6734-8

Ho G, Narita M, Broze GJ Jr, Schwartz AL
Recombinant full-length tissue factor pathway inhibitor fails to bind to the cell surface: implications for catabolism in vitro and in vivo.
Blood 2000 Mar 15;95(6):1973-8

Han X, Girard TJ, Baum P, Abendschein DR, Broze GJ Jr
Structural requirements for TFPI-mediated inhibition of neointimal thickening after balloon injury in the rat.
Arterioscler Thromb Vasc Biol 1999 Oct;19(10):2563-7

Han X, Huang ZF, Fiehler R, Broze GJ Jr
The protein Z-dependent protease inhibitor is a serpin.
Biochemistry 1999 Aug 24;38(34):11073-8

Chan JC, Carmeliet P, Moons L, Rosen ED, Huang ZF, Broze GJ Jr, Collen D, Castellino FJ
Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit.
J Clin Invest 1999 Feb;103(4):475-82

Caplice NM, Mueske CS, Kleppe LS, Peterson TE, Broze GJ Jr, Simari RD
Expression of tissue factor pathway inhibitor in vascular smooth muscle cells and its regulation by growth factors.
Circ Res 1998 Dec 14-28;83(12):1264-70

Han X, Fiehler R, Broze GJ Jr
Isolation of a protein Z-dependent plasma protease inhibitor.
Proc Natl Acad Sci U S A 1998 Aug 4;95(16):9250-5

Baugh RJ, Broze GJ Jr, Krishnaswamy S
Regulation of extrinsic pathway factor Xa formation by tissue factor pathway inhibitor.
J Biol Chem 1998 Feb 20;273(8):4378-86

Schwartz AL, Broze GJ Jr
Tissue factor pathway inhibitor endocytosis.
Trends Cardiovasc Med 1997;7:234-239

Ho G, Broze GJ Jr, Schwartz AL
Role of heparan sulfate proteoglycans in the uptake and degradation of tissue factor pathway inhibitor-coagulation factor Xa complexes.
J Biol Chem 1997 Jul 4;272(27):16838-44

Mast AE, Higuchi DA, Huang ZF, Warshawsky I, Schwartz AL, Broze GJ Jr
Glypican-3 is a binding protein on the HepG2 cell surface for tissue factor pathway inhibitor.
Biochem J 1997 Oct 15;327 ( Pt 2):577-83

Huang ZF, Higuchi D, Lasky N, Broze GJ Jr
Tissue factor pathway inhibitor gene disruption produces intrauterine lethality in mice.
Blood 1997 Aug 1;90(3):944-51

Huang ZF, Broze GJ Jr
Consequences of tissue factor pathway inhibitor gene-disruption in mice.
Thromb Haemost 1997 Jul;78(1):699-704

Toomey JR, Kratzer KE, Lasky NM, Broze GJ Jr
Effect of tissue factor deficiency on mouse and tumor development.
Proc Natl Acad Sci U S A 1997 Jun 24;94(13):6922-6

Gailani D, Lasky NM, Broze GJ Jr
A murine model of factor XI deficiency.
Blood Coagul Fibrinolysis 1997 Mar;8(2):134-44

Broze GJ Jr, Higuchi DA
Coagulation-dependent inhibition of fibrinolysis: role of carboxypeptidase-U and the premature lysis of clots from hemophilic plasma.
Blood 1996 Nov 15;88(10):3815-23

Broze GJ Jr
Thrombin-dependent inhibition of fibrinolysis.
Curr Opin Hematol 1996 Sep;3(5):390-4

Warshawsky I, Herz J, Broze GJ Jr, Schwartz AL
The low density lipoprotein receptor-related protein can function independently from heparan sulfate proteoglycans in tissue factor pathway inhibitor endocytosis.
J Biol Chem 1996 Oct 18;271(42):25873-9

Toomey JR, Kratzer KE, Lasky NM, Stanton JJ, Broze GJ Jr
Targeted disruption of the murine tissue factor gene results in embryonic lethality.
Blood 1996 Sep 1;88(5):1583-7

Ho G, Toomey JR, Broze GJ Jr, Schwartz AL
Receptor-mediated endocytosis of coagulation factor Xa requires cell surface-bound tissue factor pathway inhibitor.
J Biol Chem 1996 Apr 19;271(16):9497-502

Mast AE, Broze GJ Jr
Physiological concentrations of tissue factor pathway inhibitor do not inhibit prothrombinase.
Blood 1996 Mar 1;87(5):1845-50

Narita M, Bu G, Olins GM, Higuchi DA, Herz J, Broze GJ Jr, Schwartz AL
Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo.
J Biol Chem 1995 Oct 20;270(42):24800-4

Broze GJ Jr
Tissue factor pathway inhibitor.
Thromb Haemost 1995 Jul;74(1):90-3

Broze GJ Jr
Tissue factor pathway inhibitor and the current concept of blood coagulation.
Blood Coagul Fibrinolysis 1995 Jun;6 Suppl 1:S7-13

Warshawsky I, Bu G, Mast A, Saffitz JE, Broze GJ Jr, Schwartz AL
The carboxy terminus of tissue factor pathway inhibitor is required for interacting with hepatoma cells in vitro and in vivo.
J Clin Invest 1995 Apr;95(4):1773-81

Luchtman-Jones L, Broze GJ Jr
The current status of coagulation.
Ann Med 1995 Feb;27(1):47-52

Broze GJ Jr, Lange GW, Duffin KL, MacPhail L
Heterogeneity of plasma tissue factor pathway inhibitor.
Blood Coagul Fibrinolysis 1994 Aug;5(4):551-9

Girard TJ, Gailani D, Broze GJ Jr
Complementary DNA sequencing of canine tissue factor pathway inhibitor reveals a unique nanomeric repetitive sequence between the second and third Kunitz domains.
Biochem J 1994 Nov 1;303 ( Pt 3):923-8

Warshawsky I, Broze GJ Jr, Schwartz AL
The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor.
Proc Natl Acad Sci U S A 1994 Jul 5;91(14):6664-8

Wesselschmidt R, Likert K, Huang Z, MacPhail L, Broze GJ Jr
Structural requirements for tissue factor pathway inhibitor interactions with factor Xa and heparin.
Blood Coagul Fibrinolysis 1993 Oct;4(5):661-9

Gailani D, Broze GJ Jr
Factor XI activation by thrombin and factor XIa.
Semin Thromb Hemost 1993;19(4):396-404

Huang ZF, Wun TC, Broze GJ Jr
Kinetics of factor Xa inhibition by tissue factor pathway inhibitor.
J Biol Chem 1993 Dec 25;268(36):26950-5

Broze GJ Jr, Gailani D
The role of factor XI in coagulation.
Thromb Haemost 1993 Jul 1;70(1):72-4

Broze GJ Jr, Likert K, Higuchi D
Inhibition of factor VIIa/tissue factor by antithrombin III and tissue factor pathway inhibitor.
Blood 1993 Sep 1;82(5):1679-81

Gailani D, Broze GJ Jr
Factor XII-independent activation of factor XI in plasma: effects of sulfatides on tissue factor-induced coagulation.
Blood 1993 Aug 1;82(3):813-9

Tyson DR, Kuppuswamy MN, Broze GJ Jr, Bajaj SP
Revised DNA sequence of exon 1 and 5' flanking region of the human tissue factor pathway inhibitor gene.
Thromb Res 1993 May 1;70(3):269-73

Gailani D, Broze GJ Jr
Effects of glycosaminoglycans on factor XI activation by thrombin.
Blood Coagul Fibrinolysis 1993 Feb;4(1):15-20

Smith RP, Broze GJ Jr
Characterization of platelet-releasable forms of beta-amyloid precursor proteins: the effect of thrombin.
Blood 1992 Nov 1;80(9):2252-60

Smith PL, Skelton TP, Fiete D, Dharmesh SM, Beranek MC, MacPhail L, Broze GJ Jr, Baenziger JU
The asparagine-linked oligosaccharides on tissue factor pathway inhibitor terminate with SO4-4GalNAc beta 1, 4GlcNAc beta 1,2 Mana alpha.
J Biol Chem 1992 Sep 25;267(27):19140-6

Wun TC, Kretzmer KK, Palmier MO, Day KC, Huang MD, Welsch DJ, Lewis C, Wolfe RA, Zobel JF, Lange GW, Frazier RB, Bild GS, Peel MS, Shell RE, Horn NA, Junger KD, Foy BA, Gustafson ME, Leimgruber RM, Novotny WF, Broze GJ Jr, Pyla YE, Kippenmeyer PJ, Warren TG
Comparison of recombinant tissue factor pathway inhibitors expressed in human SK hepatoma, mouse C127, baby hamster kidney, and Chinese hamster ovary cells.
Thromb Haemost 1992 Jul 6;68(1):54-9

Broze GJ Jr
The role of tissue factor pathway inhibitor in a revised coagulation cascade.
Semin Hematol 1992 Jul;29(3):159-69

Wesselschmidt R, Likert K, Girard T, Wun TC, Broze GJ Jr
Tissue factor pathway inhibitor: the carboxy-terminus is required for optimal inhibition of factor Xa.
Blood 1992 Apr 15;79(8):2004-10

Higuchi DA, Wun TC, Likert KM, Broze GJ Jr
The effect of leukocyte elastase on tissue factor pathway inhibitor.
Blood 1992 Apr 1;79(7):1712-9

Broze GJ Jr
Why do hemophiliacs bleed?
Hosp Pract (Off Ed) 1992 Mar 15;27(3):71-4, 79-82, 85-6

Broze GJ Jr
Tissue factor pathway inhibitor and the revised hypothesis of blood coagulation.
Trends Cardiovasc Med 1992;2:72-77

Carson SD, Haire WD, Broze GJ Jr, Novotny WF, Pirrucello SJ, Duggan MJ
Lipoprotein associated coagulation inhibitor, factor VII, antithrombin III, and monocyte tissue factor following surgery.
Thromb Haemost 1991 Nov 1;66(5):534-9

Gailani D, Broze GJ Jr
Factor XI activation in a revised model of blood coagulation.
Science 1991 Aug 23;253(5022):909-12

Girard TJ, Eddy R, Wesselschmidt RL, MacPhail LA, Likert KM, Byers MG, Shows TB, Broze GJ Jr
Structure of the human lipoprotein-associated coagulation inhibitor gene. Intro/exon gene organization and localization of the gene to chromosome 2.
J Biol Chem 1991 Mar 15;266(8):5036-41

Broze GJ Jr
Endothelial injury, coagulation and atherosclerosis.
Coronary Artery Disease 1991;2:131-140

Novotny WF, Palmier M, Wun TC, Broze GJ Jr, Miletich JP
Purification and properties of heparin-releasable lipoprotein-associated coagulation inhibitor.
Blood 1991 Jul 15;78(2):394-400

Novotny WF, Brown SG, Miletich JP, Rader DJ, Broze GJ Jr
Plasma antigen levels of the lipoprotein-associated coagulation inhibitor in patient samples.
Blood 1991 Jul 15;78(2):387-93

Gemmell CH, Broze GJ Jr, Turitto VT, Nemerson Y
Utilization of a continuous flow reactor to study the lipoprotein-associated coagulation inhibitor (LACI) that inhibits tissue factor.
Blood 1990 Dec 1;76(11):2266-71

Wesselschmidt RL, Girard TJ, Broze GJ Jr
cDNA sequence of rabbit lipoprotein-associated coagulation inhibitor.
Nucleic Acids Res 1990 Nov 11;18(21):6440

Broze GJ Jr, Girard TJ, Novotny WF
Lipoprotein-associated coagulation inhibitor.
Curr Stud Hematol Blood Transfus 1991;(58):22-5

Wun TC, Huang MD, Kretzmer KK, Palmier MO, Day KC, Bulock JW, Fok KF, Broze GJ Jr
Immunoaffinity purification and characterization of lipoprotein-associated coagulation inhibitors from Hep G2 hepatoma, Chang liver, and SK hepatoma cells. A comparative study.
J Biol Chem 1990 Sep 25;265(27):16096-101

Day KC, Hoffman LC, Palmier MO, Kretzmer KK, Huang MD, Pyla EY, Spokas E, Broze GJ Jr, Warren TG, Wun TC
Recombinant lipoprotein-associated coagulation inhibitor inhibits tissue thromboplastin-induced intravascular coagulation in the rabbit.
Blood 1990 Oct 15;76(8):1538-45

Repke D, Gemmell CH, Guha A, Turitto VT, Broze GJ Jr, Nemerson Y
Hemophilia as a defect of the tissue factor pathway of blood coagulation: effect of factors VIII and IX on factor X activation in a continuous-flow reactor.
Proc Natl Acad Sci U S A 1990 Oct;87(19):7623-7

Broze GJ Jr, Girard TJ, Novotny WF
Regulation of coagulation by a multivalent Kunitz-type inhibitor.
Biochemistry 1990 Aug 21;29(33):7539-46

Girard TJ, McCourt D, Novotny WF, MacPhail LA, Likert KM, Broze GJ Jr
Endogenous phosphorylation of the lipoprotein-associated coagulation inhibitor at serine-2.
Biochem J 1990 Sep 15;270(3):621-5

Miletich JP, Broze GJ Jr
Beta protein C is not glycosylated at asparagine 329. The rate of translation may influence the frequency of usage at asparagine-X-cysteine sites.
J Biol Chem 1990 Jul 5;265(19):11397-404

Girard TJ, MacPhail LA, Likert KM, Novotny WF, Miletich JP, Broze GJ Jr
Inhibition of factor VIIa-tissue factor coagulation activity by a hybrid protein.
Science 1990 Jun 15;248(4961):1421-4

Smith RP, Higuchi DA, Broze GJ Jr
Platelet coagulation factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein.
Science 1990 Jun 1;248(4959):1126-8

Silverman EK, Miletich JP, Pierce JA, Sherman LA, Endicott SK, Broze GJ Jr, Campbell EJ
Alpha-1-antitrypsin deficiency. High prevalence in the St. Louis area determined by direct population screening.
Am Rev Respir Dis 1989 Oct;140(4):961-6

Novotny WF, Girard TJ, Miletich JP, Broze GJ Jr
Purification and characterization of the lipoprotein-associated coagulation inhibitor from human plasma.
J Biol Chem 1989 Nov 5;264(31):18832-7

Girard TJ, Warren LA, Novotny WF, Bejcek BE, Miletich JP, Broze GJ Jr
Identification of the 1.4 kb and 4.0 kb messages for the lipoprotein associated coagulation inhibitor and expression of the encoded protein.
Thromb Res 1989 Jul 1;55(1):37-50

Girard TJ, Warren LA, Novotny WF, Likert KM, Brown SG, Miletich JP, Broze GJ Jr
Functional significance of the Kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor.
Nature 1989 Apr 6;338(6215):518-20

Gramzinski RA, Broze GJ Jr, Carson SD
Human fibroblast tissue factor is inhibited by lipoprotein-associated coagulation inhibitor and placental anticoagulant protein but not by apolipoprotein A-II.
Blood 1989 Mar;73(4):983-9

Novotny WF, Girard TJ, Miletich JP, Broze GJ Jr
Platelets secrete a coagulation inhibitor functionally and antigenically similar to the lipoprotein associated coagulation inhibitor.
Blood 1988 Dec;72(6):2020-5

Wun TC, Kretzmer KK, Girard TJ, Miletich JP, Broze GJ Jr
Cloning and characterization of a cDNA coding for the lipoprotein-associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains.
J Biol Chem 1988 May 5;263(13):6001-4

Broze GJ Jr, Warren LA, Novotny WF, Higuchi DA, Girard JJ, Miletich JP
The lipoprotein-associated coagulation inhibitor that inhibits the factor VII-tissue factor complex also inhibits factor Xa: insight into its possible mechanism of action.
Blood 1988 Feb;71(2):335-43

Strauss WM, Broze GJ Jr, Miletich JP, Null HR
Mass transfer in agarose-based immunoadsorbent columns.
Biotech Applied Biochem 1987;9:462-477

Broze GJ Jr, Warren LA, Girard JJ, Miletich JP
Isolation of the lipoprotein associated coagulation inhibitor produced by HepG2 (human hepatoma) cells using bovine factor Xa affinity chromatography.
Thromb Res 1987 Oct 15;48(2):253-9

Miletich J, Sherman L, Broze G Jr
Absence of thrombosis in subjects with heterozygous protein C deficiency.
N Engl J Med 1987 Oct 15;317(16):991-6

Scarpati EM, Wen D, Broze GJ Jr, Miletich JP, Flandermeyer RR, Siegel NR, Sadler JE
Human tissue factor: cDNA sequence and chromosome localization of the gene.
Biochemistry 1987 Aug 25;26(17):5234-8

Miletich JP, Broze GJ Jr
Human plasma protein Z antigen: range in normal subjects and effect of warfarin therapy.
Blood 1987 Jun;69(6):1580-6

Shelton-Inloes BB, Broze GJ Jr, Miletich JP, Sadler JE
Evolution of human von Willebrand factor: cDNA sequence polymorphisms, repeated domains, and relationship to von Willebrand antigen II.
Biochem Biophys Res Commun 1987 Apr 29;144(2):657-65

Broze GJ Jr, Miletich JP
Isolation of the tissue factor inhibitor produced by HepG2 hepatoma cells.
Proc Natl Acad Sci U S A 1987 Apr;84(7):1886-90

Broze GJ Jr, Miletich JP
Characterization of the inhibition of tissue factor in serum.
Blood 1987 Jan;69(1):150-5

Broze GJ Jr, Hickman S, Miletich JP
Monoclonal anti-human factor VII antibodies. Detection in plasma of a second protein antigenically and genetically related to factor VII.
J Clin Invest 1985 Sep;76(3):937-46

Broze GJ Jr, Leykam JE, Schwartz BD, Miletich JP
Purification of human brain tissue factor.
J Biol Chem 1985 Sep 15;260(20):10917-20

Broze GJ Jr, Miletich JP
Human Protein Z.
J Clin Invest 1984 Apr;73(4):933-8

Rodgers GM, Broze GJ Jr, Shuman MA
The number of receptors for factor VII correlates with the ability of cultured cells to initiate coagulation.
Blood 1984 Feb;63(2):434-8

Salem HH, Broze GJ, Miletich JP, Majerus PW
The light chain of factor Va contains the activity of factor Va that accelerates protein C activation by thrombin.
J Biol Chem 1983 Jul 25;258(14):8531-4

Salem HH, Broze GJ, Miletich JP, Majerus PW
Human coagulation factor Va is a cofactor for the activation of protein C.
Proc Natl Acad Sci U S A 1983 Mar;80(6):1584-8

Broze GJ Jr
Binding of human factor VII and VIIa to monocytes.
J Clin Invest 1982 Sep;70(3):526-35

Miletich JP, Broze GJ Jr, Majerus PW
The synthesis of sulfated dextran beads for isolation of human plasma coagulation factors II, IX, and X.
Anal Biochem 1980 Jul 1;105(2):304-10

Broze GJ Jr, Majerus PW
Purification and properties of human coagulation factor VII.
J Biol Chem 1980 Feb 25;255(4):1242-7