Lee Ratner, M.D., Ph.D.

Tsusaki K, Hermine O, Bazarbachi A, Ratner L, Ramos JC, O’Mahoney D, Bittencourt AL, Yamaguchi K, Utsunomiya A, Tobinai K, Watanabe T
Definition, prognostic factors, treatment, and reponse criteria of adult T-cell leukemia-lymphoma: a proposal from an international consensus meeting.
In press

Ratner L, Tan B
AIDS Related Malignancies.
In: The Washington Manual of Oncology, Second Edition (R Govindan, ed) Lippincott Williams and Wilkins, Chapter 30, 2007

Lairmore M, Ratner L
Cytokines in HTLV-1 cytokines and cancer.
In: Cytokines in the Genesis and Treatment of Cancer (M Caligiuri and M Lotze, eds), Humana Press Inc. USA, 2007; pp 27-51

Tan B, Ratner L
Immusupression-related malignancies.
In :DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology Review, R Govindan (ed), Lippincott, Williams & Wilkins, p 424-428

Ratner L
Human T cell lymphotropic virus-associated leukemia/lymphoma.
Curr Opin Oncol 2005 Sep;17(5):469-73

Lairmore MD, Silverman L, Ratner L
Animal models for human T-lymphotropic virus type 1 (HTLV-1) infection and transformation.
Oncogene 2005 Sep 5;24(39):6005-15

Ratner L
Pathogenesis and treatment of human T-cell leukemia virus infection.
Immunol Res 2005;32(1-3):217-24

Ratner L
Adult T cell leukemia lymphoma.
Front Biosci 2004 Sep 1;9:2852-9

Smukler AJ, Tan B, Ratner L
AIDS-related lymphomas.
Contemporary Oncology 2003 Aug 15;2:1-11

Ratner L
Tumorigenesis with transgenic expression of human T cell luekmia virus tax.
Sugamura K, ed. Two decades of adult T cell leukemia and HTLV-I research: progress in basic research and its implications in clinical advances, Gann Monograph #50 on Cancer Research, Tokyo, Japan, pp 231-240

Smukler AJ, Ratner L
Hepatitis viruses and hepatocellular carcinoma in HIV-infected patients.
Curr Opin Oncol 2002 Sep;14(5):538-42

Tan B, Ratner L
AIDS Related Malignancies.
In: Govindin R, Arquette MA, eds. Washington Manual of Oncology, Lippincott, Chapter 6, pp 100-111

Tan B, Piwnica-Worms D, Ratner L
Multidrug resistance transporters and modulation.
Curr Opin Oncol 2000 Sep;12(5):450-8

Ratner L, Portis T, Robek M, Harding J, Grossman W
Studies of the immortalizing activity of HTLV type 1 Tax, using an infectious molecular clone and transgenic mice.
AIDS Res Hum Retroviruses 2000 Nov 1;16(16):1647-51

Ratner L, Robek M, Grossman W
Role of Tax in HTLV-1 transformation: studies with an infectious proviral clone and transgenic mice.
In:  Hammarskjold M-L and Semmes OJ, Molecular Pathogenesis of HTLV-1,Vandamere Press, p 131-136, 1998

Tan B, Ratner L
The use of new antiretroviral therapy in combination with chemotherapy.
Curr Opin Oncol 1997 Sep;9(5):455-64

Harada S, Ratner L
AIDS 1997. Virology: overview.
AIDS 1997;11 Suppl A:S1-2

Ratner L, Fenyo EM
Virology.
AIDS 1996;10 Suppl A:S1-2

Grossman WJ, Ratner L
Transgenic mouse models for HTLV-I infection.
J Acquir Immune Defic Syndr Hum Retrovirol 1996;13 Suppl 1:S162-9

Ratner L
Genetic organization of HIV.
In: Gupta A, Immunology of HIV Infection, Plenum Press, New York, pp. 3-22, 1996

Ratner L
Animal models of HTLV-1 infection.
In: Hollsberg P, ed. Human T-cell Lymphotropic Viruses, Chap 12, John Wiley & Sons, Ltd, pp 287-307, 1996

Ratner L, Niederman TM
Nef.
Curr Top Microbiol Immunol 1995;193:169-208

Lilenbaum RC, Ratner L
Systemic treatment of Kaposi's sarcoma: current status and future directions.
AIDS 1994 Feb;8(2):141-51

Ratner L
Viral life cycle and genetic approaches.
Perspectives in Drug Discovery and Design. 1:3-22, 1993

Ratner L
Molecular biology and pathogenesis of HIV.
In: Burke D, ed. HIV Infections and AIDS. Current Opinion in Infectious Diseases vol 6, no 2, 6:181-190, 1993

Ratner L
CNS lymphomas associated with AIDS.
In: Levine AJ, Schmidek HH, eds. Molecular Genetics of Nervous System Tumors, Wiley-Liss, New York, Chap 30, pp 329-340, 1992

Bryant ML, Ratner L
Biology and molecular biology of human immunodeficiency virus.
Pediatr Infect Dis J 1992 May;11(5):390-400

Niederman TM, Ratner L
Functional analysis of HIV1 and SIV Nef proteins.
Res Virol 1992 Jan-Feb;143(1):43-6

Ratner L
Glucosidase inhibitors for treatment of HIV-1 infection.
AIDS Res Hum Retroviruses 1992 Feb;8(2):165-73

McNearney T, Ratner L
HIV sequence heterogeneity, diverse levels of diversity.
AIDS Targeted Information Newsletter, Sept. 1991

Ratner L, Niederman TJ, Lozeron H, Bryant M.
Structure and function of HIV and SIV nef protducts.
In: Haseltine W, ed. The Genetic Structure and Regualtion of HIV, Raven Press, New York pp 437-450, 1991

Ratner L, Niederman TJ, Lozeron H, Bryant M.
Structure and fucntion of the negative factor (NEF) of HIV and SIV.
In: Kumar A, ed. Advances in Molecular Biology and Targeted Treatment of AIDS. Plenum Press, pp 203-216, 1991

Bryant M, Ratner L
The biology and molecular biology of HIV.
In Pizzo PA, Wilfert CA, eds. Pediatric AIDS: The Challenge of HIV Infection in Infants, Children, and Adolexcents. Williams & Wilkins, pp 53-74, 1990

Ratner L
Molecular variation among HTLV isolates.
In: Blattner W, ed. Human Retrovirology, HTLV, Raven Press, New York, pp 49-64, 1990

Ratner L, Wong-Staal F
Human T-lymphotropic retroviruses (HTLV-I, HTLV-II).
In: O'Brien S, ed. Genetic Maps, Cold Spring Harbor Press, 5th edition, pp 1.160-1.161, 1990

Ratner L
Role of the negative factors (NEF) in HIV and SIV replication.
AIDS Targeted Information Newsletter 3:1-2, March 1989

Ratner L
Measurement of human immunodeficiency virus load and its relation to disease progression.
AIDS Res Hum Retroviruses 1989 Apr;5(2):115-9

Ratner L
Human immunodeficiency virus-associated autoimmune thrombocytopenic purpura: a review.
Am J Med 1989 Feb;86(2):194-8

Ratner L
The human immunodeficiency virus protease and its role in virus replciation.
Minireview. AIDS Targeted Information Newsletter. 2:1-2, February 1988

Ratner L
The family of immunosuppressive human retroviruses.
Minireview. AIDS Targeted Information Newsletter 1:1-3, June, 1987

Ratner L
Is the HIV envelope guilty of murder?
Minireview. AIDS Targeted Information Newsletter 1:1-2, January 1987

Ratner L, Sodroski JG, Wong-Staal F, Haseltine WA, Shaw GM, Gallo RC
Mechanism of leukemogenesis by human T-cell leukemia virus types I and II: role of the lor gene.
Cancer Detect Prev 1987;10(5-6):411-24

Ratner L, Fisher A, Jagodzinski LL, Liou RS, Mitsuya H, Gallo RC, Wong-Staal F
Complete nucleotide sequences of functional clones of the virus associated with the acquired immunodeficiency syndrome, HTLV-III/LAV.
Hamatol Bluttransfus 1987;31:404-6

Ratner L, Haseltine W, Patarca R, Livak KJ, Starcich B, Josephs SF, Doran ER, Rafalski A, Whitehorn EA, Baumeister K, Ivanoff L, Petteway SR, Pearson ML, Lauenberger JA, Papas TS, Ghrayeb J, Chang NT, Callo RC, Wong-Staal F
Complete nucleotide sequence of the AIDS virus, HTLV-III.
In: Rivera DS, ed. 1986 Year Book of Cancer, Houston, U of Texas, MD Anderson Hospital Scientific Publications.

Ratner L, Gallo RC
Human T cell lymphotropic viruses and their family of diseases.
In: Notkins AB, Oldstone MB, eds. Concepts in Clinical Pathogenesis II. New York, Springer-Verlag, pp 257-260, 1985

Ratner L, Gallo RC
Structure and function of human retroviruses.
In: Gustafson JP, ed. Genetics, Molecules, and Evolution. New York, Plenum Publishing, pp 307-342, 1985

Wong-Staal F, Ratner L, Shaw G, Hahn B, Harper M, Franchini G, Gallo R
Molecular biology of human T-lymphotropic retroviruses.
Cancer Res 1985 Sep;45(9 Suppl):4539s-4544s

Ratner L, Josephs SF, Wong-Staal F
Oncogenes: their role in neoplastic transformation.
Annu Rev Microbiol 1985;39:419-49

Gallo RC, Ratner L, Popovic M, Salahuddin SZ, Sarngadharan MG, Wong-Staal F, Shaw G, Hahn B, Markam PD, Groopman J, Safai B, Reitz M, Robert-Guroff M
The family of human T-lymphotropic retroviruses called human T-cell leukemia/lymphoma virus (HTLV): their role in lymphoid malignancies and lymphosuppressive disorders (AIDS).
In: Marks PA, ed. Genetics, Cell Differentiation, and Cancer, New York, Academic Press, 1985

Ratner L, Wong-Staal F, Gallo RC
Oncogenes and cellular transformation by human T-cell leukemia virus.
In: Andersson LC, Gahmberg CG, Ekbom P, eds. Gene Expression During Normal and Malignant Differentiation. Academic Press, pp. 183-209, 1985

Ratner L, Sarin PS, Wong-Staal F, Gallo RC
Human and primate T-lymphotropic retroviruses (HTLV & PTLV) subtypes, biological activity, and role in neoplasms.
In: Rigby WJ, Wilkie NM, eds. Viruses and Cancer. Cambridge University Press, pp 261-289, 1985

Ratner L, Arya S, Wong-Staal F, Gallo RC
Cellular transformation by human T-cell leukemia virus: possible role of T-cell growth factor and platelet-derived growth factor.
In: Czech MP, Kahn CR, eds. Membrane Receptors and Cellular Recognition, UCLA Symposia on Molecular and Cellular Biology, New Series, vol 23, New York, Alan R Liss, Inc pp 357-367, 1985

Ratner L, Gallo RC, Wong-Staal F
Cloning human oncogenes.
In: Becker E, ed. Recombinant DNA Research, Martinus Nijhoff Publishing, pp. 15-35, 1985

Wong-Staal F, Hahn BH, Shaw GM, Arya SK, Harper M, Gonda M, Gilden R, Ratner L, Starcich B, Okamoto T, et al.
Molecular characterization of human T-lymphotropic leukemia virus type III associated with the acquired immunodeficiency syndrome.
Princess Takamatsu Symp 1984;15:291-300

Lengyel P, Desrosiers R, Broeze R, Slattery E, Taira H, Dougherty J, Samata H, Pichon J, Farrell P, Ratner L, Sen GC
Biochemistry of the interferon system.
Microbiology, pp. 219, 1980

Sen GC, Desrosiers R, Ratner L, Shaila S, Brown GE, Lebleu B, Slattery E, Kawakita M, Cabrer B, Taira H, Lengyel P
Messenger RNA methylation, translation and degradation in extracts of interferon-treated cells.
Tex Rep Biol Med 1977;35:221-9

Lengyel P, Sen GC, Desrosiers R, Ratner L, Shaila S, Brown GE, Lebleu B, Kawakita M, Cabrer B, Taira H, Slattery E
Double stranded RNA and the mechanism of interferon action, a progress report.
In: Chakravorty M, ed. Molecular Basis of Host-Virus Interaction. Princeton, New Jersey, Science Press, 1976