Katherine N. Weilbaecher, M.D.

Hernandez JM, Floyd DH, Weilbaecher KN, Green PL, Boris-Lawrie K
Multiple facets of junD gene expression are atypical among AP-1 family members.
Oncogene 2008 Apr 21; [Epub ahead of print]

Uluckan O, Eagleton MC, Floyd DH, Morgan EA, Hirbe AC, Kramer M, Dowland N, Prior JL, Piwnica-Worms D, Jeong SS, Chen R, Weilbaecher K
APT102, a novel adpase, cooperates with aspirin to disrupt bone metastasis in mice.
J Cell Biochem 2008 Jul 1;104(4):1311-1323

Vaira S, Johnson T, Hirbe AC, Alhawagri M, Anwisye I, Sammut B, O'Neal J, Zou W, Weilbaecher KN, Faccio R, Novack DV
RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation.
Proc Natl Acad Sci U S A 2008 Mar 11;105(10):3897-902

Apicelli AJ, Maggi LB Jr, Hirbe AC, Miceli AP, Olanich ME, Schulte-Winkeler CL, Saporita AJ, Kuchenreuther M, Sanchez J, Weilbaecher K, Weber JD
A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function.
Mol Cell Biol 2008 Feb;28(3):1068-80

Sprague JE, Kitaura H, Zou W, Ye Y, Achilefu S, Weilbaecher KN, Teitelbaum SL, Anderson CJ
Noninvasive imaging of osteoclasts in parathyroid hormone-induced osteolysis using a 64Cu-labeled RGD peptide.
J Nucl Med 2007 Feb;48(2):311-8

Hirbe AC, Rubin J, Uluckan O, Morgan EA, Eagleton MC, Prior JL, Piwnica-Worms D, Weilbaecher KN
Disruption of CXCR4 enhances osteoclastogenesis and tumor growth in bone.
Proc Natl Acad Sci U S A 2007 Aug 28;104(35):14062-7

Watson MA, Ylagan LR, Trinkaus KM, Gillanders WE, Naughton MJ, Weilbaecher KN, Fleming TP, Aft RL
Isolation and molecular profiling of bone marrow micrometastases identifies TWIST1 as a marker of early tumor relapse in breast cancer patients.
Clin Cancer Res 2007 Sep 1;13(17):5001-9

Hirbe AC, Uluckan O, Morgan EA, Eagleton MC, Prior JL, Piwnica-Worms D, Trinkaus K, Apicelli A, Weilbaecher K
Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner.
Blood 2007 Apr 15;109(8):3424-31

Gauvain KM, Garbow JR, Song SK, Hirbe AC, Weilbaecher K
MRI Detection of Early Bone Metastases in B16 Mouse Melanoma Models.
Clin Exp Metastasis 2005 Sep;22(5):403-411

Gao L, Deng H, Zhao H, Hirbe A, Harding J, Ratner L, Weilbaecher K
HTLV-1 tax transgenic mice develop spontaneous osteolytic bone metastases prevented by osteoclast inhibition.
Blood 2005 Aug 23; Epub ahead of print

Bakewell SJ, Nestor P, Prasad S, Tomasson MH, Dowland N, Mehrotra M, Scarborough R, Kanter J, Abe K, Phillips D, Weilbaecher KN
Platelet and osteoclast beta3 integrins are critical for bone metastasis.
Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14205-10

Sheffield MV, Yee H, Dorvault CC, Weilbaecher KN, Eltoum IA, Siegal GP, Fisher DE, Chhieng DC
Comparison of five antibodies as markers in the diagnosis of melanoma in cytologic preparations.
Am J Clin Pathol 2002 Dec;118(6):930-6

Granter SR, Weilbaecher KN, Quigley C, Fisher DE
Role for microphthalmia transcription factor in the diagnosis of metastatic malignant melanoma.
Appl Immunohistochem Mol Morphol 2002 Mar;10(1):47-51

Selzer E, Wacheck V, Lucas T, Heere-Ress E, Wu M, Weilbaecher KN, Schlegel W, Valent P, Wrba F, Pehamberger H, Fisher D, Jansen B
The melanocyte-specific isoform of the microphthalmia transcription factor affects the phenotype of human melanoma.
Cancer Res 2002 Apr 1;62(7):2098-103

Dorvault CC, Weilbaecher KN, Yee H, Fisher DE, Chiriboga LA, Xu Y, Chhieng DC
Microphthalmia transcription factor: a sensitive and specific marker for malignant melanoma in cytologic specimens.
Cancer 2001 Oct 25;93(5):337-43

Weilbaecher KN, Motyckova G, Huber WE, Takemoto CM, Hemesath TJ, Xu Y, Hershey CL, Dowland NR, Wells AG, Fisher DE
Linkage of M-CSF signaling to Mitf, TFE3, and the osteoclast defect in Mitf(mi/mi) mice.
Mol Cell 2001 Oct;8(4):749-58

Motyckova G, Weilbaecher KN, Horstmann M, Rieman DJ, Fisher DZ, Fisher DE
Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family.
Proc Natl Acad Sci U S A 2001 May 8;98(10):5798-803

Granter SR, Weilbaecher KN, Quigley C, Fletcher CD, Fisher DE
Microphthalmia transcription factor: not a sensitive or specific marker for the diagnosis of desmoplastic melanoma and spindle cell (non-desmoplastic) melanoma.
Am J Dermatopathol 2001 Jun;23(3):185-9

Granter SR, Weilbaecher KN, Quigley C, Fletcher CD, Fisher DE
Clear cell sarcoma shows immunoreactivity for microphthalmia transcription factor: further evidence for melanocytic differentiation.
Mod Pathol 2001 Jan;14(1):6-9

King R, Googe PB, Weilbaecher KN, Mihm MC Jr, Fisher DE
Microphthalmia transcription factor expression in cutaneous benign, malignant melanocytic, and nonmelanocytic tumors.
Am J Surg Pathol 2001 Jan;25(1):51-7

King R, Weilbaecher KN, McGill G, Cooley E, Mihm M, Fisher DE
Microphthalmia transcription factor. A sensitive and specific melanocyte marker for MelanomaDiagnosis.
Am J Pathol 1999 Sep;155(3):731-8

Price ER, Horstmann MA, Wells AG, Weilbaecher KN, Takemoto CM, Landis MW, Fisher DE
alpha-Melanocyte-stimulating hormone signaling regulates expression of microphthalmia, a gene deficient in Waardenburg syndrome.
J Biol Chem 1998 Dec 4;273(49):33042-7

Weilbaecher KN, Hershey CL, Takemoto CM, Horstmann MA, Hemesath TJ, Tashjian AH, Fisher DE
Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3.
J Exp Med 1998 Mar 2;187(5):775-85

Jasmer RM, Larson MS, Weilbaecher KN
Porphyria cutanea tarda and hepatitis C virus infection in a patient with acute liver failure.
West J Med 1994 Nov;161(5):513-5

Weilbaecher K, Weissman I, Blume K, Heimfeld S
Culture of phenotypically defined hematopoietic stem cells and other progenitors at limiting dilution on Dexter monolayers.
Blood 1991 Aug 15;78(4):945-52

Namikawa R, Weilbaecher KN, Kaneshima H, Yee EJ, McCune JM
Long-term human hematopoiesis in the SCID-hu mouse.
J Exp Med 1990 Oct 1;172(4):1055-63

Furley AJ, Chan LC, Mizutani S, Ford AM, Weilbaecher K, Pegram SM, Greaves MF
Lineage specificity of rearrangement and expression of genes encoding the T cell receptor-T3 complex and immunoglobulin heavy chain in leukemia.
Leukemia 1987 Sep;1(9):644-52

Furley AJ, Mizutani S, Weilbaecher K, Dhaliwal HS, Ford AM, Chan LC, Molgaard HV, Toyonaga B, Mak T, van den Elsen P, et al.
Developmentally regulated rearrangement and expression of genes encoding the T cell receptor-T3 complex.
Cell 1986 Jul 4;46(1):75-87