Tanner Johanns.jpg

Tanner M. Johanns, MD, PhD

Fourth-year (T32 Program) Fellow
Began fellowship in 2014


BA, University of St. Thomas, St. Paul, MN
MD, PhD, University of Minnesota, Minneapolis, MN
Post-graduate Training
Residency, Barnes-Jewish Hospital, St. Louis, MO


  • Targeting Neoantigens in Glioblastoma: An Overview of Cancer Immunogenomics and Translational Implications
    Johanns TM, Bowman-Kirigin JA, Liu C, Dunn GP
    Neurosurgery 2017 Sep 1;64(CN_suppl_1):165-176
  • Management of Intracranial Melanomas in the Era of Precision Medicine
    Young GJ, Bi WL, Wu WW, Johanns TM, Dunn GP, Dunn IF
    Oncotarget 2017 Jul 13; [Epub ahead of print]
  • Applied Cancer Immunogenomics: Leveraging Neoantigen Discovery in Glioblastoma
    Johanns TM, Dunn GP
    Cancer J 2017 Mar/Apr;23(2):125-130
  • Endogenous Neoantigen-Specific CD8 T Cells Identified in Two Glioblastoma Models Using a Cancer Immunogenomics Approach
    Johanns TM, Ward JP, Miller CA, Wilson C, Kobayashi DK, Bender D, Fu Y, Alexandrov A, Mardis ER, Artyomov MN, Schreiber RD, Dunn GP
    Cancer Immunol Res 2016 Dec;4(12):1007-1015
  • Immune Checkpoint Inhibition in Patients With Brain Metastases
    Johanns T, Waqar SN, Morgensztern D
    Ann Transl Med 2016 Oct;4(Suppl 1):S9
  • Immunogenomics of Hypermutated Glioblastoma: A Patient With Germline POLE Deficiency Treated With Checkpoint Blockade Immunotherapy
    Johanns TM, Miller CA, Dorward IG, Tsien C, Chang E, Perry A, Uppaluri R, Ferguson C, Schmidt RE, Dahiya S, Ansstas G, Mardis ER, Dunn GP
    Cancer Discov 2016 Nov;6(11):1230-1236
  • Identification of Neoantigen-Specific CD8+ T Cells in Two Murine Orthotopic Glioblastoma Models Using Cancer Immunogenomics
    Johanns TM, Ward J, Wilson C, Kobayashi DK, Bender D, Fu Y, Alexandrov A, Artyomov MN, Miller CA, Mardis ER, Dunn GP
    Neurosurgery 2016 Aug;63 Suppl 1, Clinical Neurosurgery:158
  • High Incidence of TERT Mutation in Brain Tumor Cell Lines
    Johanns TM, Fu Y, Kobayashi DK, Mei Y, Dunn IF, Mao DD, Kim AH, Dunn GP
    Brain Tumor Pathol 2016 Jul;33(3):222-7
  • Selective Culling of High Avidity Antigen-Specific CD4+ T Cells After Virulent Salmonella Infection
    Ertelt JM, Johanns TM, Mysz MA, Nanton MR, Rowe JH, Aguilera MN, Way SS
    Immunology 2011 Dec;134(4):487-97
  • Early Eradication of Persistent Salmonella Infection Primes Antibody-Mediated Protective Immunity to Recurrent Infection
    Johanns TM, Law CY, Kalekar LA, O'Donnell H, Ertelt JM, Rowe JH, Way SS
    Microbes Infect 2011 Apr;13(4):322-30
  • Interleukin (IL)-21-Independent Pathogen-Specific CD8+ T-Cell Expansion, and IL-21-Dependent Suppression of CD4+ T-Cell IL-17 Production
    Ertelt JM, Johanns TM, Rowe JH, Way SS
    Immunology 2010 Oct;131(2):183-91
  • Naturally Occurring Altered Peptide Ligands Control Salmonella-Specific CD4+ T Cell Proliferation, IFN-Gamma Production, and Protective Potency
    Johanns TM, Ertelt JM, Lai JC, Rowe JH, Avant RA, Way SS
    J Immunol 2010 Jan 15;184(2):869-76
  • Regulatory T Cell Suppressive Potency Dictates the Balance Between Bacterial Proliferation and Clearance During Persistent Salmonella Infection
    Johanns TM, Ertelt JM, Rowe JH, Way SS
    PLoS Pathog 2010 Aug 12;6(8):e1001043
  • Cytotoxic T-Lymphocyte Antigen 4 Blockade Augments the T-Cell Response Primed by Attenuated Listeria Monocytogenes Resulting in More Rapid Clearance of Virulent Bacterial Challenge
    Rowe JH, Johanns TM, Ertelt JM, Lai JC, Way SS
    Immunology 2009 Sep;128(1 Suppl):e471-8
  • Selective Priming and Expansion of Antigen-Specific Foxp3- CD4+ T Cells During Listeria Monocytogenes Infection
    Ertelt JM, Rowe JH, Johanns TM, Lai JC, McLachlan JB, Way SS
    J Immunol 2009 Mar 1;182(5):3032-8
  • PDL-1 Blockade Impedes T Cell Expansion and Protective Immunity Primed by Attenuated Listeria Monocytogenes
    Rowe JH, Johanns TM, Ertelt JM, Way SS
    J Immunol 2008 Jun 1;180(11):7553-7
  • Glutamate-Induced Protease-Mediated Loss of Plasma Membrane Ca2+ Pump Activity in Rat Hippocampal Neurons
    Pottorf WJ 2nd, Johanns TM, Derrington SM, Strehler EE, Enyedi A, Thayer SA
    J Neurochem 2006 Sep;98(5):1646-56
  • Activation of Protein Kinase C in Sensory Neurons Accelerates Ca2+ Uptake Into the Endoplasmic Reticulum
    Usachev YM, Marsh AJ, Johanns TM, Lemke MM, Thayer SA
    J Neurosci 2006 Jan 4;26(1):311-8
  • Restricted STAT5 Activation Dictates Appropriate Thymic B Versus T Cell Lineage Commitment
    Goetz CA, Harmon IR, O'Neil JJ, Burchill MA, Johanns TM, Farrar MA
    J Immunol 2005 Jun 15;174(12):7753-63