Hematology Research / Work-In-Progress Seminar

Scroll down to:   A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Speaker Index

Speaker Date Title
A
Abdul-Nabi, Anmaar Oct 10, 2008 Molecular and Biological Effects of AML-associated Fusion Proteins on Primary Human CD34+ Cells
Abendschein, Dana Apr 17, 2015 Can We Inhibit Thrombosis Without Increasing Bleeding?
Ailhaud, Gerard Mar 23, 2001 Early Events and Redundancy in Adipogenesis
Alford, Shannon Sep 14, 2007 Sphingosine 1-phosphate-mediated Endothelial Cell Migration in Human Platelet Poor Plasma
Amend, Sarah Mar 2, 2012 Identification of the Genetic Basis of MGUS and Multiple Myeloma Susceptibility in KaLwRij Mice
Jan 25, 2013 Of Mice and Men: Genetic Contributions of Susceptibility to MGUS, the Requisite Precursor of Multiple Myeloma
Anbukumar, Dhanam Feb 3, 2012 Calcium Binding Studies of von Willebrand Factor Propeptide
Nov 16, 2012 Characterizing VWF Propeptide Ca2+ Binding Sites
Dec 20, 2013 Cation Dependence of vWF Multimerization
Oct 17, 2014 A Calcium Conundrum: The Role of Calcium in VWF Multimerization
Dec 10, 2015 The ATP7A Copper Transporter Is Required for VWF Multimerization
Sep 22, 2016 Copper Transport in Von Willebrand Factor Biosynthesis
Nov 2, 2017 The Involvement of Copper Transport in Von Willebrand Factor Biosynthesis
Mar 21, 2019 The Function of Copper Ions in vWF Multimer Assembly
Anderson, Richard Apr 21, 2006 Phosphoinositide Signaling: From Biochemistry to Human Disease
Anderson, Trish Jan 21, 2005 Work-in-Progress
Mar 30, 2007 ADAMTS13 Structure and Function
Feb 29, 2008 ADAMTS13 Spacer Domain and Substrate Recognition
Dec 12, 2008 Substrate Recognition by the ADAMTS13 Spacer Domain
Dec 11, 2009 More on ADAMTS13 Spacer Domain and VWF Substrate Recognition
Andrews, Nancy Oct 22, 1993 An Erythroid Transcription Factor Regulating Globin Gene Expression and Iron Metabolism
Oct 23, 1998 Iron Deficiency and Iron Overload: Insights From Anemic Animals
Armanios, Mary Jan 31, 2019 The Telomere Syndromes: Implications for Patient Care
Feb 10, 2020 The Telomere Syndromes: A Paradigm for Molecular Medicine
Arora, Vivek Dec 17, 2015 Defining Novel Oncogenic Drug Targets in Bladder Cancer
Ataga, Kenneth Feb 28, 2020 Meeting Unmet Needs in Sickle Cell Disease
Atkinson, John May 18, 2001 Immune Adherence Revisited
Oct 14, 2005 HUS: Not Enough Regulation of Innate Immunity
Apr 6, 2012 Atypical Hemolytic Uremic Syndrome
B
Baenziger, Jacques May 7, 1999 The Sulfated Oligosaccharides on LH Reveal the Roles Played by Glycosylation During the Reproductive Cycle
Oct 5, 2007 Carbohydrates Determine Hormone Potency in Vivo
Apr 18, 2014 Molecular Multi-Tasking: New Insights Into Hepatic Glycan Receptor Function
Baeten, Jeremy Mar 4, 2021 TP53 in Clonal Hematopoiesis
Baldo, Guilherme May 13, 2011 Pathogenesis of the Aortic Valve Disease in MPS VII
Bankaitis, Vytas Apr 26, 1996 Phosphatidylinositol Transfer Proteins: a New Class of Intracellular Regulatory Molecules
Dec 5, 2007 A High Resolution Look at a Superfamily of Nanoreactors That Control Phosphoinositide Signaling in Eukaryotic Cells
Baranski, Tom Feb 25, 2000 Genetic Analysis of G Protein Signalling
Nov 7, 2003 Understanding the Receptor Switch: How Do Hormones Activate G Proteins?
Barnes, Terra (with Stuart Kornfeld) Jan 14, 2011 The Mannose 6-Phosphate Lysosomal Targeting Pathway and Persistent Stuttering
Bassler, Bonnie L. Sep 22, 2017 9th Rosalind Kornfeld Lecture: Bacterial Quorum Sensing and Its Control
Batista, Luis Mar 21, 2013 Human IPS Cells as a Model to Study Telomere Dysfunction-Induced Disease
May 29, 2015 Generation of an Isogenic Model to Study the Consequences of Telomerase Mutations in Human Stem Cells
Bednarski, Jeffrey Sep 29, 2016 Physiologic and Genotoxic DNA Damage Activate Distinct Cellular Responses in Developing B Lymphocytes
Beerman, Isabel Mar 8, 2016 Hematopoietic Stem Cell Aging
Berrien-Elliott, Melissa Apr 18, 2019 miR-142 Is Required for NK Cell Homeostasis and Function
Bertina, Rogier Apr 11, 1997 Genetic Analysis of Inherited Thrombophilia
Bessler, Monica Nov 8, 1996 Molecular Basis of Paroxysmal Nocturnal Hemoglobinuria
Oct 17, 1997 A Mouse Model for Paroxysmal Nocturnal Hemoglobinuria: Use of the Cre/LoxP System to Circumvent Embryonic Lethality
Mar 26, 1999 Clonal Evolution in Paroxysmal Nocturnal Hemoglobinuria
Nov 3, 2000 PNH: the Human Disease and Animal Models
Nov 1, 2002 Bone Marrow Failure and Telomerase
Jan 14, 2005 Paroxysmal Nocturnal Hemoglobinuria - From Bench to Bedside
Apr 6, 2007 Housekeeping Ain't No Joke! the Importance of Ribosome Biogenesis in Human Blood Disorders
Apr 3, 2009 Towards a New Understanding of Bone Marrow Failure
Bhattacharya, Deepta Feb 7, 2014 Convergent Differentiation During Hematopoiesis
Bigg, Paul Dec 17, 2010 The Pathogenesis of Mitral Valve Disease in Mucopolysaccharidosis VII Dogs
Blumer, Ken May 7, 2004 RGS Proteins: New Regulators of Blood Pressure Homeostasis and G Protein-Mediated Vasoconstrictor Signaling
Bock, Paul Sep 22, 2006 Blood Coagulation Out of Control: Molecular Sexuality Mechanism of Prothrombin Activation by Staphylocoagulase
Bock, Susan Apr 22, 1994 Antithrombin III and Serpin Structure/Function Studies
Boonen, Marielle Oct 2, 2009 Mucolipidosis Type II Mice Accumulate Autophagolysosomes in Fibroblasts and Serous/mucous Type Secretory Cells
Mar 20, 2015 Cathepsin D and Neuronal Differentiation: Lessons From the Identification of a New Binding Partner
Bose, Ron Mar 11, 2011 Kinase Activation and Signaling: How Does the Her2 Tyrosine Kinase Give Rise to Breast Cancer?
Boucher, Paul Mar 11, 2021 Adenoviral Vector Mediated Gene Editing of the B Cell Receptor as an HIV Vaccine
Brachmann, Rainer Oct 9, 1998 Yeast as a Genetic Tool to Study the Tumor Suppressor Protein P53
Sep 28, 2001 Stories of and Around P53
Brass, Skip May 6, 2011 Dynamic Regulation of Platelet Accumulation Following Vascular Injury
Bray, Paul Oct 10, 2014 Platelet PAR4 Functional Genomics: Racial Disparities in Anti-Platelet Therapy
Mar 31, 2016 Plateletomics: Exploring Platelet Biology Via Multi-omic Data Integration
Bredemeyer, Andrea Oct 15, 2020 Generation of Yolk-Sac-Like and Definitive Macrophages From Human PSCs
Brenner, Kirsten Feb 13, 2015 Regulation of the Telomerase RNA Component TERC in Human Development and Disease
Mar 24, 2016 Telomere-Independent Functions of the Telomerase RNA Component in Human Stem Cells
Oct 20, 2016 Telomere-independent Functions of the Telomerase RNA Component in Human Stem Cells
Oct 12, 2017 A Telomere-Independent Role for the Telomerase RNA Component in Human Embryonic Stem Cells
Sep 27, 2018 A Telomere-Independent Role for the Telomerase RNA Component in Human Embryonic Stem Cells
Brost, Taylor May 19, 2016 Interrogation of Genetically Distinct Clones Using MPN Patient-Specific IPSCs
Brown, Ric Dec 9, 1994 Signal Transduction by Leukocyte Integrins
Broze, George Oct 4, 1996 Effects of Tissue Factor and Tissue Factor Pathway Inhibitor Gene Deletion
Dec 18, 1998 What About Protein Z?
Oct 20, 2000 Protein Z and Thrombosis
Dec 13, 2002 Regulation of Coagulation by Protein Z
Apr 22, 2005 TFPI α and β
Mar 9, 2007 Protein Z-Dependent Protease Inhibitor
Sep 25, 2009 Regulation of Coagulation
Dec 10, 2010 Tissue Factor Pathway Inhibitor
Feb 15, 2013 Translational Studies of Tissue Factor Inhibitors
Bruchas, Michael Jan 26, 2017 Dissecting Neuromodulatory Circuits in Affective Behavior
Brugge, Joan Mar 18, 2020 Oxidative Stress Defenses in Cancer
Brunelli, Angelo Jan 21, 2021 Pevonedistat Targets Malignant Cells in Myeloproliferative Neoplasms in Vitro and in Vivo Via NFkB Pathway Inhibition
Bu, Guojun Apr 9, 2004 The LDL Receptor Family: What These Receptors Don't Do
Byun, Minji Nov 5, 2015 Searching for the Genetic Etiology of Infectious Diseases
C
Camargo, Fernando Nov 17, 2016 Clonal Analysis of Native Hematopoiesis
Challen, Grant Dec 13, 2013 The Epigenetics of Hematopoietic Stem Cell Self-Renewal and Transformation
Chan, Andy Mar 4, 1994 Protein Tyrosine Kinases in T Cell Activation: Bench to Bedside
Chang, Sandy May 7, 2010 How Telomeres Repress the DNA Damage Response
Chang, Shao-Chun Sep 10, 2004 The Pathway to Inositol Hexakisphosphate Synthesis
Chavez, Monique Oct 29, 2020 Investigating Lenalidomide Treatment-Based Secondary B-Cell Acute Lymphoblastic Leukemia
Cheng, Emily Sep 24, 2004 Apoptotic Checkpoints at the Mitochondrion
Dec 14, 2007 Regulation of Cell Death by BCL-2 Family and Beyond
Cherian, Mathew Mar 1, 2013 Role of PI3K-Akt-mTOR in HTLV-Tax Induced Transformation
Apr 25, 2014 Role of the PI3K-Akt mTOR Pathway in Human T Cell Leukemia Induced Transformation
Mar 13, 2015 Role of the PI3K-Akt-mTOR Pathway in HTLV Induced Leukemogenesis
Cheung, Vivian G. Oct 27, 2017 45th Carl Moore Lecture: It's in the RNA: Implications for Human Disease
Chheda, Milan Feb 9, 2017 Developing a Synthetic Lethal Genetic Screen to Identify Vulnerabilities in IDH1 Mutant Gliomas
Choi, Jaebok Jan 20, 2012 Interferon Gamma Receptor Signaling and T Cell Trafficking in Graft vs. Host Disease
Choi, Kyunghee Apr 20, 2012 Regulation of Hematopoietic and Vascular Development
Cho, Jaehyung (Gus) Feb 14, 2020 Mechanisms Regulating Intravascular Cell-Cell Interactions in Thrombosis and Inflammation
Christopher, Matt Apr 10, 2015 Cold Shock Domain Proteins in Normal and Malignant Hematopoiesis
Feb 11, 2016 WT1 in Normal and Malignant Hematopoiesis
Clevers, Hans Mar 2, 2016 43rd Carl Moore Lecture: Lgr5 Stem Cell-Grown Organoids and Their Applications
Cocco, Lucio Apr 30, 2010 Nuclear Phospholipase C Beta1 Signalling, MDS and AML: From Bench to Clinics
Cole, Christopher Mar 22, 2013 Role of DNMT3A in Acute Promyelocytic Leukemia
Mar 28, 2014 The Role of Dnmt3a in Acute Promyelocytic Leukemia
Collier, Timothy May 3, 2013 Probing the Structure and Dimerization of EGFR Family Tyrosine Kinases
Collins, Taylor Feb 16, 2017 Utilizing iPSCs as a Model System to Interrogate Genetically Distinct Clones in Myeloproliferative Neoplasms
Oct 5, 2017 Interrogation of ASXL1 Mutations in Combination With the JAK2 V617F Mutation in MPNs
Dec 13, 2018 Interrogation of ASXL1 Mutations in Combination With the JAK2 V617F Mutation in MPNs
Sep 19, 2019 Interrogating the Role of ASXL1 and JAK2 Mutations in MPNs Utilizing Human Pluripotent Stem Cells
Cooper, John Jan 19, 1996 Control of Actin Assembly by Capping Protein
Cottrell, Kyle Apr 18, 2019 Upregulation of 5'TOP mRNAs Following Loss of the Tumor Suppressor ARF
Crabtree, Gerald Nov 9, 2012 40th Carl Moore Lecture: Chromatin Regulation: New Methods and Concepts
Creamer, Philip Feb 1, 2018 Investigating Gene Expression During Human Definitive Hematopoietic Specification
Feb 14, 2019 Defining the Role of CDX4 During Human Definitive Hematopoietic Specification
Crowley, Stephanie May 13, 2021 BCLAF1 Regulation of Hematopoietic Stem Cell Repopulating Capacity
Cummings, Rick Feb 2, 1996 The Glycobiology of Schistosomiasis: From Molecular Mimicry to Autoimmunity
D
Dahms, Nancy Feb 27, 1998 Insight Into Lysosomal Enzyme Recognition by the Mannose 6-Phosphate Receptors
Dang, Luke Mar 19, 2010 Two Histidine Residues Required for the pH Dependent Multimerization of Von Willebrand Factor
Das Thakur, Meghna Mar 16, 2007 The Role of LIM Proteins in Cell-Cell Adhesion and Epithelial Polarity
May 16, 2008 Role of the Ajuba LIM Protein in Size Control in Drosophila Epithelia
Davidson, Nick May 30, 2003 RNA Editing: Molecular Mechanisms and Biological Consequences
Day, Ryan Feb 4, 2021 Distinct Profiles of CBF Leukemias
Dean, Doug Feb 16, 1996 Mechanism of Action of the Retinoblastoma Tumor Suppressor
Oct 26, 2001 The Role for Rb in Tumor Suppression
Dege, Carissa May 5, 2016 Characterization of Human Pluripotent Stem Cell Derived Natural Killer Cells
Oct 27, 2016 Generation and Characterization of Human Pluripotent Stem Cell-derived Natural Killer Cells
Oct 12, 2017 Natural Born Killers? Determining Function and Ontological Origins of Two Distinct Natural Killer Cell Populations Derived From Human Pluripotent Stem Cells
Sep 27, 2018 Ontogeny Is a Critical Determinant of Human Pluripotent Stem Cell Derived Natural Killer Cell Function
Oct 3, 2019 Potently Cytotoxic Natural Killer Cell Potential Initially Emerges From Erythro-Myeloid Progenitors During Mammalian Development
Degen, Jay May 10, 1996 Hard Knocks to the Hemostatic Balance: Fibrinogen and Plasminogen Deficiency in Mice
DeNardo, David Sep 6, 2013 Reprogramming Macrophages to Improve Responses to Chemo- and Immunotherapy
DePinho, Ronald Dec 8, 2000 28th Carl Moore Lecture: Telomerase, Tumor Suppressors and Tumorigenesis
Deuel, Tom Mar 29, 1996 Mechanisms of Transcriptional Regulation by the Wilms Tumor Suppressor Gene
Jun 1, 2011 Shaping the Tumor Phenotype and Microenvironment: New Pathways, New Therapeutic Targets
DeWeerd, Rachel Mar 18, 2021 The Experimentally-Defined APOBEC3A Signature Is Prevalent in Human Cancers
Di Cera, Enrico Feb 13, 1998 Thrombin Allostery
Oct 8, 2004 Rational Design of a Thrombin Mutant With Potent and Safe Anticoagulant/Antithrombotic Activity in Vivo
Diacovo, Tom Dec 10, 1999 Platelets and the Molecular and Cellular Interactions Governing Their Adhesion: From Arterial Injury to Venular Inflammation
Dick, John Nov 19, 1993 Modeling Normal and Leukemic Hematopoiesis in SCID Mice
Dietz, Hal Nov 19, 2010 38th Carl Moore Lecture: TGFβ in the Pathogenesis and Prevention of Aneurysm: Embracing Paradox
Dinauer, Mary Mar 9, 2012 Getting a License to Kill: Regulation of the Leukocyte NADPH Oxidase
DiPaola, Jorge Jan 7, 2019 Studying Megakaryocytes, From Inherited Disorders to Old Age Platelets
DiPersio, John Dec 19, 1997 Cytokine Signaling Pathways
Dolatshahi, Leili Feb 22, 2013 Adjuvant Low Dose Rituximab for Patients with TTP
Doray, Balraj Jan 7, 2005 Work-in-Progress
Mar 3, 2006 Work-in-Progress
Feb 2, 2007 The α/σ2 Hemicomplex of Clathrin Adaptor AP-2 Harbors the Dileucine Recognition Site
Oct 26, 2007 Identification of Acidic-dileucine Signals That Bind to GGAs and AP-1/AP-2
Feb 13, 2009 Understanding the GGA Null Phenotype
Dec 11, 2009 Characterization of Mouse GGA2 Antibodies
Mar 4, 2011 GGA Autoinhibition Re-revisited: Do Internal Dileucines Bind GGA VHS Domains
Feb 17, 2012 GGA Null Mice: The Final Chapter? Or Not?
Jan 11, 2013 Gga2 Knockout Mice Revisited
Dec 20, 2013 Influence of Genetic Background on Lethality of GGA2 Knockout Mice
Nov 14, 2014 Assembly of UDP-GlcNAc-1-Phosphotransferase, a Multi-Subunit Protein
Sep 10, 2015 Understanding How GlcNAc-1-Phosphotransferase Recognizes Lysosomal Enzymes: Part I
Doudna, Jennifer Nov 13, 2015 8th Rosalind Kornfeld Lecture: The CRISPR-Cas9 Genome Engineering Revolution
Druker, Brian Mar 3, 2000 CML and STI 571: Validating the Promise of Molecularly Targeted Therapy
Dubielecka, Patrycja Oct 17, 2019 Signaling at the Crossroads: From Inflammaging to Cancer
Duckett, Colin Apr 24, 2001 Role of IAP Proteins in the Control of Cell Survival
Du, Hong-Yan Oct 28, 2005 Work-in-Progress
Feb 9, 2007 TERT Haploinsufficiency and Telomere Length in Individuals with 5p- Syndrome
Jan 18, 2008 The Significance of Telomere Length Measurement in the Diagnosis of Dyskeratosis Congenita
Duncavage, Eric Feb 28, 2014 Detection of Subclonal Population in MDS
Oct 31, 2014 Sequencing Based Detection of Low Frequency Variants in MDS
Dustin, Mike Jun 4, 1999 Visualizing Molecular Events in the Immune Response: Building an Immunological Synapse
Du, Xiaoping Sep 2, 2021 Novel Mechanisms of Integrin Outside-In Signaling and the Concept of Treating Thrombosis and Inflammation Without Causing Bleeding
E
Elefanty, Andrew Aug 30, 2018 Dissection of Human Haematopoiesis From Pluripotent Stem Cells
Ellenberger, Tom Feb 8, 2008 Chemical Biology of DNA Repair
Ellisen, Leif Mar 24, 2000 Acute Leukemia, Telomeres and DNA Damage Responses
Ellis, Matthew Oct 4, 2013 The Genomics and Proteomics of Breast Cancer
Engle, Elizabeth May 3, 2013 Genetic Complexity and Clonal Evolution in Myeloproliferative Neoplasms
May 23, 2014 Genetic Complexity and Disease Evolution in Myeloproliferative Neoplasms
Feb 27, 2015 Intersection of Dysregulated Cytokines and Signaling in Myeloproliferative Neoplasms
Epple, Holly May 5, 2006 Work-in-Progress
Jan 19, 2007 From the Skeleton to the Cytoskeleton: Mechanisms of Osteoclast Function
F
Fager, Ammon Jan 11, 2016 Human Platelets Express Endothelial Protein C Receptor Which Contributes to the Binding and Activity of rFVIIa
Fehniger, Todd Nov 1, 2013 Molecular Regulation of NK Cell Development and Function
Feng, Yunfeng May 13, 2005 Work-in-Progress
Oct 13, 2006 RNAi Oriented Loss of Function Research on α-Actinin
Feb 29, 2008 Regulation of Cell Migration by α-actinin
Feys, Hendrik May 16, 2008 Understanding ADAMTS13 When Under (Shear) Stress
Field, Joshua Apr 4, 2014 The Potential Role of Invariant NKT Cells in Sickle Cell Disease
Fields, Melanie May 8, 2015 MR Measurements of Cerebral Blood Flow and Oxygen Extraction Fraction in Pediatric Sickle Cell Disease
Apr 21, 2016 Functional Connectivity in Sickle Cell Disease
Mar 30, 2017 Cerebral Oxygen Metabolism and Vasoreactivity in Sickle Cell Disease
Fisher, Daniel Jan 20, 2012 Mass Cytometry Study of Human Myeloproliferative Neoplasia
Oct 26, 2012 Genomic Study of Myeloproliferative Neoplasia
Feb 14, 2014 Signaling in Myeloproliferative Neoplasms Studied by Single Cell Mass Cytometry
Sep 26, 2014 Mass Cytometry Study Identifies NFκB Signaling as a Potential Disease Driver in Myeloproliferative Neoplasms
Sep 10, 2015 NFkB Hyperactivation in Myeloproliferative Neoplasms
Apr 13, 2017 Cytokines and Intracellular Signaling Abnormalities in Myeloproliterative Neoplasms
Jan 25, 2018 Utilizing Mass Cytometry and Mouse Models to Understand Myeloproliferative Neoplasms
Jan 24, 2019 Interacting Roles of Hyperactive Signaling and Cytokine Overproduction in Myeloproliferative Neoplasms
Jan 30, 2020 NFκB Hyperactivation in Myeloproliferative Neoplasms: Insights From Human Patients and Mouse Models
Sep 17, 2020 NF kappa B Hyperactivation in Myeloproliferative Neoplasms
Sep 23, 2021 JAK2 and NF Kappa B Hyperactivation in Mouse Hematopoiesis and Myeloproliferative Neoplasms
Flaumenhaft, Robert Mar 9, 2020 Test Tube to Trial: Protein Disulfide Isomerase as an Antithrombotic Target
Fleischman, Angela Sep 28, 2017 Inflammation as a Driver of Clonal Expansion in Myeloproliferative Neoplasm
Fok, Wilson Nov 14, 2014 Telomere Dysfunction in Stem Cell Proliferation and Differentiation
Oct 15, 2015 Telomere Dysfunction in Stem Cell Proliferation and Differentiation
Sep 22, 2016 p53 Stabilization Following Progressive Telomere Shortening Differentially Regulates Human Hematopoietic Specification
Oct 5, 2017 Understanding How Telomere Dysfunction and RNA Processing Defects Lead to Human Disease
Oct 25, 2018 Inhibition of Polyadenylation Activity by Silencing of PAPD5 Restores Telomerase and Rescues Hematopoietic Failure in Dyskeratosis Congenita
Fowles, Jared Apr 27, 2017 Genomic Dissection of Age-Related Differences in Polycythemia Vera
Feb 1, 2018 Genomic Dissection of Age-Related Differences in Polycythemia Vera
Feb 21, 2019 Investigating the Genomic and Inflammatory Profiles of Young and Old Polycythemia Patients
Nov 5, 2020 Dysregulated Inflammation in Myeloproliferative Neoplasms and Disease Progression
Frazier, Bill Oct 13, 1995 Thrombospondin as a Regulator of Endothelial Phenotype
Mar 22, 2002 Integrin Associated Protein (CD47): a Receptor With Multiple Roles in Vascular Disease
French, Anthony Apr 3, 2015 Regulation of NK Cell Proliferation
Friedman, Jeffrey Oct 24, 1997 25th Carl Moore Lecture: Leptin, Leptin Receptors and the Control of Body Weight
Fuh, Katherine Mar 31, 2016 Functional Genomics of Ovarian Cancer Metastasis
Fujiki, Yukio Mar 5, 2010 Peroxisome Biogenesis and Its Dysfunctions in Humans
G
Gadue, Paul J. Apr 5, 2018 Megakaryocyte Development From Stem Cell Sources
Gailani, Dave Apr 7, 1995 The Role of Factor XI in a Revised Model of Blood Coagulation
Mar 26, 2010 Factor XI and the Intrinsic Pathway in Normal and Pathologic Coagulation
Ganem, Donald Nov 21, 2008 36th Carl Moore Lecture: Small Noncoding RNAs and the Biology of Kaposi's Sarcoma-Associated Herpesvirus
Ganz, Tomas Jan 23, 2015 Systemic Iron Homeostasis and Its Disorders
Gao, Weiqiang Oct 21, 2005 Work-in-Progress
Sep 15, 2006 A C-terminal Exosite of von Willebrand Factor Domain A2 Interacts with ADAMTS13 Spacer Domain to Accelerate Substrate Cleavage
Oct 26, 2007 Contacts Between Several ADAMTS13 Structural Domains and Von Willebrand Factor Domain A2 Contribute to Substrate Cleavage
Apr 10, 2009 Fluorescent VWF Substrates for ADAMTS13
May 21, 2010 Functional Differences of the Non-Catalytic Domains in Human ADAMTS13 and ADAMTS5 in Substrate Cleavage
Ge, Jingping May 4, 2007 Study of the Function of Dyskerin in a Liver Specific Knock-out Mouse Model
Apr 11, 2008 Is Dyskerin Essential for Cell Survival and Proliferation?
Jan 30, 2009 Microarray Analysis of snoRNA Expression in Dyskerin Knockout Mice
Feb 5, 2010 The Consequences of Dyskerin Ablation in Mouse Liver
Germain, David May 23, 2014 DNMT3A Mutations in AML
Geuze, Hans Dec 16, 1993 New Observations on the Class II Compartment in B Lymphoblasts
Gilligan, Diana Mar 7, 2000 Knockout of Beta-Adducin Causes Spherocytosis in Mice
Gilliland, Gary Oct 14, 1994 Early Mutations in Leukemia
Ginsburg, David Feb 21, 2003 Disorders of Hemostasis Due to Genes Outside of the Coagulation System
Jan 7, 2021 FV/FVIII and Cargo Receptors in the ER: From Bedside to Bench
Girard, Tom Jan 7, 2011 The Ups and Downs of Protein Z and the Z-dependent Protease Inhibitor
Feb 3, 2012 Tissue Factor Pathway Inhibitor - βefore and αfter
Nov 16, 2012 Protein Z, Protein Z-Dependent Protease Inhibitor (SerpinA10) and the Acute Phase Response
Oct 25, 2013 Tissue Factor Pathway Inhibitor Structures, Functions and Physiology
Sep 5, 2014 Impact of Coagulation Regulators in Mouse Models of Various Diseases
Dec 10, 2015 Evaluating Blockade of the Protein Z-Dependent Protease Inhibitor Pathway as a Potential Treatment for Hemophilia
Jan 12, 2017 The Roles of Tissue Factor Pathway Inhibitor in Health and Disease
Feb 15, 2018 A Balance Between Pro- and Anti-Coagulant Factors to Abate Bleeding and Avoid Thrombosis
May 2, 2019 The TFPIαβ (γKO) Mouse Is a Better Model for Studying Human TF-Related Diseases
Giri, Tusar Mar 10, 2006 Work-in-Progress
Gitlin, Jonathan May 9, 1997 Aceruloplasminemia
Oct 6, 2000 The Copper Chaperones
May 2, 2008 Copper Homeostasis in Early Development
Goate, Alison Jan 13, 2006 A Novel Risk Factor for Alzheimer's Disease on Chromosome 10
Goldberg, Dan Apr 24, 1998 The Pathway of Hemoglobin Degradation in the Malaria Parasite P. falciparum
Jan 10, 2003 Falciparum Malaria: a Hematological Infectious Disease
Apr 4, 2008 Targeting Intraerythrocytic Malaria Parasites for Chemical Destruction
Dec 14, 2012 Trial by Fire and Famine: How the Malaria Parasite Survives in Its Host Erythrocyte
Goldsmith, Mark Jun 9, 1994 Structure/Function Relationships Within the IL-2 Receptor Complex
Gopalan, Priya Oct 10, 2008 Regulation of Hematopoietic Stem Cells by the Bone Marrow Niche
Govero, Jennifer Apr 18, 2008 Characterization of the GGA Null Mice
Nov 14, 2008 Characterization of the GGA Null Mice
Mar 19, 2010 All GGAs Are Not Created Equal
Feb 4, 2011 Strain Dependent Lethality of GGA2 Null Mice: Embryonic vs Neonatal
Grainger, Stephanie Apr 20, 2021 From Fish to Dish and Back Again: Deciphering Wnt/Fzd Cues in Hematopoietic Stem Cell Development
Graubert, Tim Mar 14, 2003 Modeling T(8;21) Associated Acute Myelogenous Leukemia in Mice
May 23, 2008 Genetic Basis of Susceptibility to Therapy-Related Leukemia
Greenberg, Zev Feb 28, 2019 Regulation of Early B Cell Development by the Tetraspanin CD53
Jan 30, 2020 Loss of CD53 Impairs B Cell Migration
Green, Eric Nov 11, 2005 33rd Carl Moore Lecture: Comparative Genomics: Using Evolution to Decode the Human Genome
Grierson, Patrick May 9, 2019 Overcoming the MK2/ Hsp27 Axis to Potentiate the Effect of Chemotherapy in Pancreatic Ductal Adenocarcinoma (PDAC)
Jan 9, 2020 The MK2/Hsp27 Axis Determines Sensitivity to Chemotherapy in Pancreatic Ductal Adenocarcinoma
Gu, Baiwei Oct 27, 2006 Molecular Mechanism of Mouse Dyskerin Mutation in Telomere Maintenance and Ribosomal RNA Processing
Oct 12, 2007 Dyskerin, Telomerase and DNA Damage
Sep 19, 2008 Is Dyskerin Crucial for Telomere Maintenance, DNA Damage Response and Ageing?
Sep 18, 2009 DNA Damage Accumulation, Accelerated Hematopoietic Stem Cell Aging, and Partial Reversal by Antioxidant Treatment in a Mouse Model of Dyskeratosis Congenita
Gu, Minxiang Jun 12, 1998 Characterization of a Novel Protein Tyrosine Phosphatase - PTPMEG
Gupta, Garima Mar 1, 2013 Non-catalytic Interaction Between VWF and ADAMTS-13
H
Hahn, William Apr 21, 2000 Telomerase Immortality in Cancer
Hajjar, Kathy Apr 8, 1994 Annexin II: a New Thromboregulatory Protein?
Halldorsdottir, Anna Margret Sep 30, 2005 Work-in-Progress
Hambleton, Julie Apr 5, 1996 Activation of MAP Kinase Signaling Pathways in Monocyte/Macrophage Cells
Hancock, John Mar 3, 1995 Ras Proteins: Membrane Targeting and Biochemical Function
Sep 17, 1999 Caveolae, Cholesterol and Trafficking: New Insights Into Biological Differences Between the Ras Proteins
Harris, David May 23, 1997 Prion Diseases: a Cell Biological Perspective
Feb 22, 2002 Molecular Mechanisms Underlying Familial Prion Diseases
He, Fan Feb 11, 2021 The Characteristics of Platelets in Essential Thrombocythemia
Heinecke, Jay Jan 11, 2002 Regulation of Matrix Metalloproteinase Activation and Plaque Rupture by Myeloperoxidase
He, Jun Feb 18, 2005 Work-in-Progress
May 19, 2006 Work-in-Progress
Heldermon, Coy Sep 5, 2008 The Effect of Bone Marrow Transplant and Intracranial Gene Therapy in Mucopolysaccharidosis IIIB Mice
He, Li Apr 29, 2005 Work-in-Progress
Herzog, Brett Oct 24, 2019 Reactive Fibrosis in Lung Cancer: Impact on Immunity and Progression
Apr 15, 2021 Restoring Immune-Mediated Tumor Control in the Fibrotic NSCLC Microenvironment
Heslop, Helen Apr 21, 1995 Use of Virus-Specific Cytotoxic T Lymphocytes to Control Epstein-Barr Virus-Related Lymphoproliferation
High, Katherine Apr 12, 1996 Gene Therapy for Hemophilia
Jan 25, 2012 Biologic Therapeutics/Hematology Joint Seminar: in Vivo Gene Transfer for Genetic Disease: Progress and Challenges
Hiken, Jeff Mar 16, 2007 Proteomic Analysis of PNH RBCs
Feb 15, 2008 Label-free Quantitative Proteomic Analysis of Normal and PNH RBC Membranes
Oct 24, 2008 Quantitative Differences Between Expression Profiles of RBC Proteomes
Hirbe, Angela May 9, 2014 Defining the Molecular Events Underlying Malignant Transformation in NF1-related MPNSTs Through Whole Genome Sequencing
Mar 13, 2015 Whole Exome Sequencing Reveals the Temporal Sequence of Genetic Changes During Malignant Transformation and Metastasis in a Single Patient With NF1-Associated Plexiform Neurofibroma
Hobbs, Helen Nov 12, 2019 Mechanisms of Lipid Accumulation: Implications for Fatty Liver Disease
Hockemeyer, Dirk Feb 13, 2020 Elucidating the Mechanisms of Cancer Cell Immortality
Hoffmeister, Karin Feb 17, 2020 Glycans in Translational and Clinical Research
Hofmann, Sandra May 9, 1996 Palmitoyl-Protein Thioesterase and the Pathogenesis of INCL
Sep 19, 2014 Phil Majerus Symposium: Molecular Basis of Infantile Batten Disease
Hogg, Phil Apr 3, 2002 Control of Von Willebrand Factor Multimer Size by Thrombospondin-1
Horwich, Arthur Nov 16, 2007 35th Carl Moore Lecture: Protein Folding and Misfolding in the Cell
Howe, Ruth May 14, 2010 The Role of Cathepsin S and MMP-12 in MPS VII Aortic Disease
Hsieh, Jim Nov 5, 2004 Taspase1 Cleaves Mixed-Lineage Leukemia Proto-Oncogene
Jan 25, 2008 Taspase1 Links MLL Proteolysis to Cell Cycle Progression and Beyond
Huang, Jing Mar 2, 2007 αvβ3 Integrin is Involved in the Stabilization of Shear-induced Ultra-long VWF Strings on Endothelial Surface
Nov 9, 2007 The B Subunits of Shiga Toxins Induce Von Willebrand Factor Secretion and Cytoskeletal Remodeling in Human Endothelial Cells
Oct 24, 2008 The B-subunits of Shiga-like Toxins 1 and 2 Promote VWF Secretion Via a Cholesterol Sensitive, Clathrin-independent Mechanism in Human Endothelial Cells
Oct 2, 2009 The B Subunits of Type 1 and Type 2 Shiga-like Toxins Induce Regulated VWF Secretion in a Phospholipase D Dependent Manner
Sep 17, 2010 The B Subunits of Shiga-like Toxins Induce Regulated VWF Secretion in a Phospholipase D1 Dependent Manner
Sep 16, 2011 Cells as a Model System to Study Weibel-Palade Body Targeting and Regulated Secretion of Ultra-large von Willebrand Factor
Sep 28, 2012 Distinct Functions of pH-Sensing Histidine Residues in the Multimer Assembly and Storage of von Willebrand Factor in Weibel-Palade Bodies
Sep 20, 2013 The Distinct Role of Two pH Sensing Histidines in the Multimer Assembly and Tubular Storage of von Willebrand Factor
Huang, Ren-Huai Feb 24, 2006 Work-in-Progress
Feb 2, 2007 How VWF Propeptide and D'D3 Domain Assemble the Storage Rings in Weibel-Palade Bodies
Sep 14, 2007 Assembly and Structure of Von Willebrand Factor Tubules in Weibel-Palade Bodies
Sep 19, 2008 Structural Basis of VWF for Aptamer Binding and Tubular Storage
Sep 18, 2009 A Structural Explanation for the Antithrombotic Activity of ARC1172, a DNA Aptamer that Binds Von Willebrand Factor Domain A1
Feb 18, 2011 Calcium and pH-Dependent Interactions Within VWF Tubule
Dec 2, 2011 Von Willbrand Factor Assembly by D-domains Before Furin Cleavage
Oct 12, 2012 How Von Willebrand Factor is Condensed into Weibel-Palade Bodies
Nov 8, 2013 VWF Tubular Assembly in Vitro by D Domains
Sep 5, 2014 The Role of D Domains in VWF Tubule Assembling
Jan 28, 2016 pH-Dependent Association Within N-terminal D Domains of Von Willebrand Factor
Hugge, Chris Apr 15, 2005 Work-in-Progress
Hultgren, Scott Mar 12, 2004 Intracellular Bacterial Communities in Bacterial Infections
I
Idol, Rachel May 12, 2006 Work-in-Progress
Jan 12, 2007 Investigations of Ribosomal Biogenesis in Diamond Blackfan Anemia
Sep 28, 2007 Human Ribosomal Biogenesis
Feb 27, 2009 A Mouse Model of Diamond Blackfan Anemia
Apr 2, 2010 Mouse Models of Diamond Blackfan Anemia
May 27, 2011 Phenotypic Analysis of Phosphotransferase Deficient Mice
May 11, 2012 Uncovering New Phenotypes in Uncovering Enzyme-Deficient Mice
Apr 19, 2013 CNS Defects in Mice Lacking Mannose-6-Phosphate
Iglesia, Michael Apr 22, 2021 Breast Cancer Subtype Heterogeneity at the Single-Cell Level
Ihle, Jim Oct 21, 1994 JAKs and STATs in Cytokine Signaling
Ikawa, Yogi Nov 21, 1995 A Possible New Erythropoietin Receptor Signaling Pathway in Friend Erythroleukemia
Ikeda, Kazuhiko Apr 18, 2008 Overexpression of HMGA2 in Normal and PNH Hematopoietic Cells
Dec 12, 2008 Overexpression of HMGA2 in Normal and PNH Hematopoiesis
Jan 8, 2010 Myeloproliferative Neoplasm-like Hematopoiesis in Mice with Truncated Hmga2 cDNA
Iliopoulos, Othon Feb 18, 2000 Functional Analysis of the Von Hippel-Lindau Tumor Suppressor Protein
Imai, Shin-Ichiro Feb 10, 2012 Towards Productive Aging: the Importance of SIRT1 and NAMPT-Mediated NAD Biosynthesis in the NAD World
J
Jacoby, Meagan Mar 13, 2009 DNA Repair Genes in Treatment-related AML and MDS
Jan 21, 2011 DNA Repair Dysfunction in Primary Therapy-related AML/MDS Myeloblasts
Mar 30, 2012 Dysfunctional Double Strand Break Repair is Present in a Subset of Therapy-related MDS/AML Myeloblasts
Feb 22, 2013 Dysfunctional Double Strand Break Repair in Therapy-related AML
Apr 11, 2014 Investigating DNA Double-Strand Break Repair in MDS and AML
Jagannathan, Radhika Mar 4, 2011 Negative Regulation of the Salvador-Warts-Hippo Pathway by the Ajuba LIM Family of Proteins
Dec 16, 2011 Negative Regulation of the Hippo Pathway by the Ajuba LIM Family of Proteins
Jasinski, Marek Mar 18, 2005 Work-in-Progress
Jay, Patrick Sep 24, 2015 Solving Congenital Heart Disease
Jefferson, A. B. Sep 29, 1995 Cell Signalling and the Inositol Polyphosphate 5-Phosphatase Isozymes
Jennings, Ben Dec 12, 2019 Identifying Molecular Mechanisms Regulating the Localization of Golgi Glycosyltransferases
Oct 1, 2020 Molecular Mechanisms Regulating the Localization of SARS-CoV2 Spike Protein and Golgi Glycosyltransferases
Jeong, Hochang Apr 25, 2019 Determining Therapeutic Targets to Restore Hematopoietic Output in Dyskeratosis Congenita
Jan 9, 2020 USB1 Mutation Causes Defective Hematopoiesis
Jan 28, 2021 Human ESC Modeling of Poikiloderma With Neutropenia Unveils Defective Hematopoietic Development Caused by Mutation in USB1
Sep 16, 2021 USB1 Is a miRNA Deacetylase That Regulates Hematopoietic Development
Jha, Vishwanath May 20, 2021 Role of Platelet ERO1α in Platelet Activation and Arterial Thrombosis
Jin, Bo Apr 27, 2007 Studies on the von Willebrand Factor Cysteine Knot Domain
Mar 28, 2008 Structural Basis of VWF Cleavage by ADAMTS13
Jin, Ramon Dec 12, 2019 Patient-Derived Organoids to Study Barrett’s Esophagus and Esophageal Carcinogenesis
Apr 8, 2021 The Role of SOX2 in Barrett's Esophagus and Esophageal Adenocarcinoma
Johanns, Tanner May 5, 2016 An Immunogenomic Approach to Identify Glioblastoma-Specific CD8 T Cells
Feb 2, 2017 Effect of Prior Radiation on Gliomagenesis and Tumor Immunity
Dec 14, 2017 Neoantigens as Therapeutic Targets in Glioblastoma
K
Kadyrov, Farid Jan 14, 2021 The Effects of Hypoxia on Monocyte/Macrophage Specification and Function During Ischemic Heart Injury
Kang, Yoon Mar 30, 2021 Who Does the Work? Lineage-Biased MPPs Tailor Blood Production
Karue, Julie May 14, 2010 Function of the N-terminal Domain of Heparin Cofactor II
Katerndahl, Casey Apr 26, 2018 The Mechanisms Underlying PML-RARA-Induced Transformation and Self-Renewal
May 9, 2019 The Mechanisms Underlying PML-RARA-Induced Self-Renewal and Transformation
Kaufman, Charles Mar 23, 2017 Key Events During Cancer Initiation: From Melanocyte to Melanoma
Kaufman, Randal May 20, 1994 Regulation of Protein Transport Through the Endoplasmic Reticulum Mediated by BiP
Kaushansky, Ken Nov 4, 1994 The Molecular and Cellular Biology of Thrombopoietin, the MPL-Ligand
Keating, Mark Nov 19, 1999 27th Carl Moore Lecture: Molecular and Cellular Mechanisms of Cardiac Arrhythmias
Kelly, Dan Apr 23, 1999 The Role of PPAR Alpha as a 'Lipostat' Transcription Factor
Mar 26, 2004 PPAR Gamma Coactivator-1 (PGC-1): an Inducible Regulator of Cardiac Mitochondrial Biogenesis and Function
Kenyon, Cynthia Jan 6, 2012 4th Rosalind Kornfeld Lecture: Genes and Cells That Affect the Rate of C. Elegans' Aging
Kharas, Michael Apr 14, 2016 RNA Binding Proteins and the Control of the Leukemic Stem Cell Program
Khoriaty, Rami Jul 20, 2016 Congenital Dyserythropoietic Anemia Type II and Transport of Proteins from the ER to Golgi
Kim, Alfred Jan 14, 2016 Glomerular Podocyte Cytokine Signaling Drives Proteinuria: Implications in Nephrotic Syndromes
Kim, Brian Jan 21, 2016 Immune Regulation of Atopic and Chronic Itch
Kim, Jongseong Jan 15, 2013 Single-Molecule Mechanobiology of Von Willebrand Factor (VWF) to Arbitrate Between Bleeding, Hemostasis, and Thrombosis
Kisseleva, Marina Feb 4, 2005 Work-in-Progress
Oct 27, 2006 Macrophages Plagued by LIM Protein Deficiency
Jan 8, 2010 Regulation of Nuclear PI(5)P in Stress Signaling
Oct 15, 2010 O, Brother, Where Art Thou? MTMR8 and MTMR9 Journey Inside the Cell
Klausner, Richard Nov 15, 1996 24th Carl Moore Lecture
Koenig, Andrew Feb 18, 2021 Cellular Atlas of the Failing Human Heart
Kohn, Donald Nov 17, 1995 Gene Therapy With Hematopoietic Stem Cells
Koh, Won Kyun Sep 24, 2020 Non-Canonical Role of DNMT3A in HSC Function
Sep 30, 2021 Non Canonical Role of DNMT3A in HSC Function
Kolhouse, Fred Mar 18, 1994 The Mechanism of Cellular Uptake of Folate and Methotrexate in Human Cells
Kopan, Raphael Mar 10, 2000 Signaling Through Notch - a Proteolytic Cascade Regulating Cell Fate
Feb 13, 2004 Multiple Roles for Notch in Mouse Development and Tissue Renewal
Kornfeld, Kerry Nov 20, 1998 A Modular System of Docking Sites Mediates MAP Kinase Recognition of Substrate Proteins
Jan 29, 2010 The Role of Zinc in Animal Development and Physiology
Kornfeld, Rosalind Feb 7, 1997 Enzymes of Glycoprotein Oligosaccharide Processing
Jan 29, 1999 Cloning and Expression of N-Acetylglucosamine-1-Phosphodiester α-N-Acetylglucosaminidase, a Key Enzyme in Formation of the Mannose-6-Phosphate Targeting Signal
Sep 22, 2000 The Mannose 6-Phosphate "Uncovering Enzyme" Resides in the Trans-Golgi Network
Kornfeld, Stuart (with Terra Barnes) Jan 14, 2011 The Mannose 6-Phosphate Lysosomal Targeting Pathway and Persistent Stuttering
Kornfeld, Stuart Oct 18, 1996 Protein Trafficking To and From Lysosomes
Apr 9, 1999 Clathrin-Coated Vesicle Formation on Liposomes and Golgi Membranes
Nov 17, 2000 The Assembly of Clathrin-Coated Vesicles on Golgi Membranes
Oct 11, 2002 GGAs - Key Players in Packaging Man-6-P Into Transport Vesicles
Mar 11, 2005 The GGA Family of Coat Proteins - Key Players in Protein Sorting at the Trans-Golgi Network
Nov 3, 2006 Toward a Chaperone-based Therapy for Gaucher Disease
Jan 20, 2009 New Insights Into the Man-6-P Lysosomal Enzyme Targeting System From Mouse Models
Feb 1, 2013 New Insights Into the Man-6-P Lysosomal Targeting Pathway Through Analysis of Mutations in I-Cell Disease and Pseudo-Hurler Polydystrophy
Feb 6, 2015 Role of the γ Subunit of UDP-GlcNAc:Lysosomal Enzyme GlcNAc-1-Phosphotransferase in Lysosomal Enzyme Phosphorylation
Kumari, Tripti Oct 21, 2021 Identification of an Inhibitor of PDI-GPIbα Signaling as a Novel Anti-Thromboinflammatory Agent
Kunter, Ghada Mar 18, 2011 Molecular Pathogenesis of Leukemia in Severe Congenital Neutropenia
L
Langer, Ellen Apr 1, 2005 Work-in-Progress
Apr 27, 2007 Ajuba LIM Proteins are Snail Corepressors that Contribute to Xenopus Neural Crest Development
Lavine, Kory Feb 18, 2016 Making Sense of Cardiac Macrophage Ontogeny and Function
Lawn, Richard Oct 28, 1993 Lipoprotein(a)
Lederkremer, Gerardo Apr 7, 1999 Location and Regulation of ER/Proteasomal Protein Quality Control
Lee, Angel Nov 12, 1993 CSF-1 Receptor: Mechanisms of Intracellular Signalling
Lee, Intaek Oct 13, 2006 Crosstalk Between Two Cargo Binding Sites of Adaptor Protein Complex AP-1
Sep 28, 2007 Binding of Cargo Sorting Signals to AP-1 Enhances its Association with ARF1-GTP
Sep 5, 2008 The Role of the Gamma-subunit of UDP-GlcNAc:lysosomal Enzyme N-acetylglucosamine-1-phosphotransferase
Lee, Wang-Sik Feb 4, 2005 Work-in-Progress
Mar 30, 2007 Studies of a Mouse Model with I-cell Disease and Pseudo-Hurler Polydystrophy
Apr 25, 2008 IFG, a Potential Therapeutic Agent for Gaucher Disease, Reduces Cholesterol Accumulation in Neimann-Pick C1 Fibroblasts
May 8, 2009 The Role of the γ-Subunit of GlcNAc-Phosphotransferase
Oct 1, 2010 Update of the Uncovering Enzyme Research with Stutterers’ mutations
Sep 16, 2011 Update on Studies of Mutations Found in the Gene Encoding Uncovering Enzyme in Individuals with Persistent Stuttering
Apr 5, 2013 Structure and Function of the DUF2233 Domain in Bacteria and in Human UCE
Apr 11, 2014 Analysis of Missense Mutations in the α,β-Subunit of GlcNAc-Phosphotransferase Associated with Stuttering
Feb 13, 2015 The Mannose 6-Phosphate Lysosomal Targeting Pathway and Persistent Stuttering
Jan 28, 2016 Role of the Subunits of GlcNAc-Phosphotransferase in Lysosomal Enzyme Recognition
Feb 27, 2020 Analysis of Lysosomal Storage Disease-Causing Missense Mutations Within the Transmembrane Domain of GlcNAc-1-Phosphotransferase
Lefkowitz, Bob Nov 16, 2001 29th Carl Moore Lecture: G Protein-Coupled Receptors and Their Regulation
Lentz, Steven Oct 24, 2001 Hyperhomocysteinemia
Feb 3, 2020 Vascular Stress Management: Oxidative Mechanisms in Thrombosis and Stroke
Levine, Beth Oct 11, 2013 6th Rosalind Kornfeld Lecture: Novel Links Between Autophagy Proteins, Cell Biology, and Metabolism
Levy, Joanne Apr 7, 2000 Iron Metabolism: Insights From Mutant Mice
Ley, Tim Jan 14, 2000 How Do Cytotoxic Lymphocytes Kill Their Target?
Dec 13, 2001 Modeling Acute Promyelocytic Leukemia in the Mouse
Oct 5, 2011 Interdisciplinary Seminar Series: the AML Genome
Li, Anguo Mar 14, 2008 Differential Gene Expression of Injured Arteries in HCII Knockout Mice
Jan 22, 2010 Activation of Heparin Cofactor II by Fibroblast Proteoglycans
Lifton, Richard Nov 8, 2002 30th Carl Moore Lecture: New Insights Into Cardiovascular, Renal, and Bone Disease From Human Genetic Studies
Lim, Kian-Huat May 1, 2015 Toll-like Receptor Signaling in Human Cancer
Linder, Maurine Mar 1, 1996 G-Protein Palmitoylation: Reversible and Regulated Acylation
Linette, Gerry Jan 25, 2002 Melanoma Cell Death
Link, Dan May 5, 1995 G-CSF Receptor Signals
Nov 14, 1997 Role of G-CSF in Hematopoiesis: Lessons From the G-CSF Receptor Knockout Mice
Mar 7, 2003 Regulation of Hematopoiesis by G-CSF
Nov 30, 2007 Regulation of the Hematopoietic Stem Cell Niche by G-CSF
Oct 8, 2010 Regulation of Stem Cell and Neutrophil Trafficking From the Bone Marrow
Oct 19, 2012 Characterizing the Stem Cell Niche
Jan 27, 2020 Pathogenesis of Congenital Neutropenia and Mechanisms of Leukemic Transformation
Lippincott-Schwartz, Jennifer Nov 6, 2020 Imaging Interacting Organelles to Understand Metabolic Homeostasis
Littman, Dan Nov 15, 2013 41st Carl Moore Lecture: Shaping of the Immune Response by the Commensal Microbiota
Liu, Chang Apr 27, 2017 Single-Molecule HLA Typing by Oxford Nonopore Technology
Mar 29, 2018 Rapid High-Resolution HLA Typing by Nanopore Sequencing
Liu, Fang Jan 4, 2008 The Characteristic of Signaling Pathways Involved in Stx B-induced von Willebrand Factor Secretion
Mar 13, 2009 Cell Signaling in Stx B Subunit-induced VWF Secretion
May 28, 2010 The Mechanism of VWF Basolateral Secretion in HUVECs
Liu, Lin Apr 7, 2016 Uncovering Novel Regulatory Roles of the "Spacer 1" Region of the GlcNAc-1-Phosphotransferase
Apr 13, 2017 Producing Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy
Apr 12, 2018 Golgi Retention of Glycosyltransferases Requires Binding of Its N-Terminal Cytoplasmic Tail to Coatomer
Li, Weikai May 4, 2012 Structure and Function of Vitamin K Epoxide Reductase: Connecting Oxidative Protein Folding With Blood Coagulation
Li, Yedda Mar 24, 2016 Combination Therapy Increases Lifespan and Improves Clinicobehavioral Performance in the Murine Model of Globoid Cell Leukodystrophy
Mar 2, 2017 Combination Therapy Improves Lifespan and Clinicobehavioral Performance in Murine Globoid Cell Leukodystrophy
Longmore, Greg Nov 1, 1996 Erythropoietin Receptor Signalling and Red Cell Development
May 8, 1998 Cytokine Regulation of Lineage Commitment During Hematopoiesis
Feb 26, 1999 Role of LIM Proteins in Cell Growth
Apr 20, 2001 Red Blood Cell Development and Leukemogenesis
Jan 24, 2003 The Role of Lim Proteins in Cell Adhesion and Motility
Dec 17, 2004 Role of LIM Proteins in Cell Adhesion and Migration
Jan 26, 2007 LIM Proteins and Epithelial Development and Cancer
Sep 11, 2009 Epithelial Morphogenesis in Development and Cancer
Jan 28, 2011 Epithelial Morphogenesis in Development and Disease
Look, Tom May 19, 1995 Chimeric Transcriptional Control Genes in Human Acute Leukemia
Lopez, Jose Apr 13, 2021 The Significance of Endothelium-Bound von Willebrand Factor
Luderer, Hilary Feb 3, 2006 Work-in-Progress
Nov 10, 2006 LIMD1: a New Key to Understanding Skeletal Dynamics
Luff, Stephanie Mar 15, 2018 Twice Spliced: Exploring HOXA9 Variants in Embryonic Hematopoiesis
Feb 28, 2019 Recapitulating Intraembryonic Hematopoiesis in the Dish
Oct 24, 2019 Top Notch Blood: The Involvement of NOTCH Signaling in Extra-Embryonic Hematopoiesis
Lunn, Cara Nov 12, 2010 Discovery of Mutations in Myelodysplastic Syndrome Genomes
Nov 11, 2011 U2AF1 Mutations in Myelodysplastic Syndromes
Sep 14, 2012 U2AF1 Splicing Factor Mutations in Myelodysplastic Syndromes
Lu, Rong Jan 3, 2013 Systems Analysis of Mouse Hematopoietic Stem Cells in Vivo at the Single Cell Level
Lyons, Susan Feb 9, 2001 Hematopoietic Studies in the Zebra Fish Model
M
MacArthur, Craig Jan 30, 1998 FGF-8 in Development and Tumorigenesis
Madison, Blair Feb 23, 2017 PLAGL2, a Zinc Finger Transcription Factor That Drives Stem Cell Identity and Colorectal Cancer Tumorigenesis
Majerus, Elaine Oct 22, 2004 Regulation of VWF Cleaving Protease (ADAMTS13) Activity
Feb 17, 2006 Work-in-Progress
May 18, 2007 Studies on ADAMTS13
Apr 17, 2009 Studies on ADAMTS13 and Protein O-Fucosyltransferase 2
Apr 8, 2011 Studies With an Enhancer of VWF Cleavage – a Novel Potential Anti-Thrombotic?
Majerus, Phil Sep 20, 1996 Role of Inositol Phosphates in Intracellular Signalling
May 21, 1999 Phosphatidyl Inositols in Cell Signaling
Apr 6, 2001 Intracellular Signaling by Inositol Phosphates
Sep 13, 2002 Inositol Signaling
Dec 10, 2004 Inositol Phosphate Signaling
Mar 23, 2007 Phosphatidylinositol Signaling and Human Disease
Jan 9, 2009 Inositols Do It All
Nov 5, 2010 Inositol Signaling in Human Disease
Mallaney, Cates Apr 25, 2014 Interactions Between Dnmt3a and Repressive Chromatin Regulate Hematopoietic Stem Cell Function and Transformation
Jan 30, 2015 Interactions Between Dnmt3a and Repressive Chromatin Regulate Hematopoietic Stem Cell Function and Transformation
Mann, Ken Dec 16, 1994 Modeling the Tissue Factor Pathway to Thrombosis: the Coagulation Explosion
Marjanovic, Jasna Apr 13, 2007 Phosphatidylinositol-5-phosphate is a Novel Phospholipase C (PLC) Substrate
Feb 15, 2008 Characterization of Myotubularin Related Protein 8
Nov 11, 2011 Work-in-Progress
Mason, Phil Nov 10, 2000 The Molecular Genetics of Dyskeratosis Congenita
Mar 6, 2003 Bone Marrow Failure Caused by Inherited Telomerase Deficiency
Mar 25, 2005 Bone Marrow Failure Caused by Inherited Defects in Telomerase
Apr 20, 2007 Telomeres, Ribosomes and Bone Marrow Failure
Nov 7, 2008 Telomeres, Ribosomes and Bone Marrow Failure
Mast, Alan Nov 19, 2015 Tissue Factor Pathway Inhibitor Biochemistry and Relation to Bleeding and Clotting Disorders
Apr 27, 2021 The TFPI Anticoagulant Activity Modulates Cerebrovascular Development
Ma, Xiucua Mar 2, 2007 Mechanism of Up-regulation of MMP-12 and Cathepsin S in the Aorta of Mucopolysaccharidosis I Mice
May 9, 2008 A Self-inactivating Retroviral Vector with Improved Safety for Gene Therapy in Mucopolysaccharidosis I Mice
McCaffrey, Anton Apr 7, 2006 Keep It Down: There's More Than One Way to Silence a Gene
McDonald, Sharon May 8, 2009 Investigating the Interaction of Dyskerin and Pot1b
McLemore, Morgan Mar 9, 2001 The Effect of Granulocyte Colony-Stimulating Factor Receptor (G-CSFR) Mutations on Granulopoiesis
McLeod, Howard Mar 8, 2002 Cancer Pharmacogenomics
Mecham, Bob Oct 27, 1995 Intracellular Forms of Extracellular Proteins: Novel Pathway for Cell Regulation
Sep 12, 2003 Developmental Adaptation of the Mouse Cardiovascular System to Elastin Haploinsufficiency
Nov 4, 2011 Regulation of Growth Factor Activity by Extracellular Matrix
Metcalf, Jason Sep 15, 2006 The Role of Fibroblast Growth Factor Signaling in Mucopolysaccharidosis Bone Defects
May 9, 2008 Pathogenesis of Short Bones in Mucopolysaccharidosis VII
May 15, 2009 A New and Safer Gene Therapy Vector for Mucopolysaccharidosis I
Michel, Loren Mar 7, 2008 Oncogenic Role and Therapeutic Targeting of the Transmembrane Protein Trop-2 in Epithelial Tumors
Mikulka, Christina Apr 26, 2018 Cell-Autonomous Expression of the Lysosomal Enzyme GALC in the Twitcher Mouse
Mar 28, 2019 Cell-Autonomous Expression of the Lysosomal Hydrolase GALC: A New Model of Krabbe Disease
Milbrandt, Jeff Nov 21, 2003 Ret Signaling in Development and Disease
Millman, Jeffrey Oct 29, 2015 Generation of Functional Human Pancreatic β Cells from Pluripotent Stem Cells In Vitro
Mills, Jason Oct 8, 2015 Stem Cells, Reprogramming, and the Origins of Cancer
Min, Sang Mar 9, 2015 Role of Phosphoinositides in Platelet-Mediated Inflammation and Thrombosis
Monlish, Darlene Oct 25, 2018 Differential Effects of TLR1/2 and TLR2/6 Signaling on Normal and Premalignant Hematopoietic Stem and Progenitor Cells
Morceau-Gaudry, Francois Nov 22, 2002 Gene Therapy of a Mouse Model of Protoporphyria With an Erythroid-Specific Lentiviral Vector
Morrissey, James Mar 23, 2012 Platelet Polyphosphate at the Nexus of Blood Clotting and Inflammation
Mosammaparast, Nima Feb 4, 2016 Ubiquitin Dependent Regulatory Mechanisms in the Alkylation Damage Response
Muglia, Lou Dec 2, 2005 Glucocorticoid Receptor Action During Inflammation
Muia, Joshua Feb 17, 2012 An Optimized Fluorogenic Assay for ADAMTS13 and Inhibitors in Thrombotic Thrombocytopenic Purpura Patients
Jan 11, 2013 pH Dependent Activity of ADAMTS13 and Self-regulatory Mechanisms
Mar 28, 2014 ADAMTS13 is Conformationally Autoinhibited by its Distal Domains and is Allosterically Activated by Von Willebrand Factor
Jan 30, 2015 Insights Into ADAMTS13 Diversity Across Multiple Animal Species
Oct 15, 2015 In Search of the Minimalist ADAMTS13 Using Evolutionary Variations in its Allosteric Properties
Oct 20, 2016 Evolution and Allosteric Regulation of ADAMTS13
Nov 30, 2017 Two Metalloproteases Involved in Cardiovascular Disease
Oct 11, 2018 Insights Into the Structure and Regulation of a Metalloprotease Involved in Cardiovascular Disease
Mullally, Ann Feb 9, 2012 Characterizing and Therapeutically Targeting MPN Stem Cells in Vivo
Mullaney, Cates Jan 7, 2016 The Role of Kdm6b in Hematopoiesis
Munroe, Michael Sep 10, 2020 Telomere Dysfunction Inpairs Hepatocyte Development and Function Via Repression of HNF4A
Murphy, Ken Mar 6, 2015 Dendritic Cell Diversification
Muslin, Tony Oct 31, 1997 The Role of 14-3-3 Protein in Ras-Mediated Signal Transduction
Oct 24, 2003 Signaling Protein Function in Cardiovascular Disease
Mysorekar, Indira Apr 20, 2017 Understanding Pathogenesis of Maternal Fetal Transmission of the Emerging Zika Virus
N
Nandakumar, Satish Feb 23, 2021 How Can We Learn About Healthy and Diseased Hematopoiesis From Human Genetic Studies?
Ndonwi, Matthew Apr 15, 2005 Work-in-Progress
Jan 20, 2006 Work-in-Progress
Mar 28, 2008 Effect of Protein S on Tissue Factor Pathway Inhibitor (TFPI) Activity
Jan 16, 2009 Malarial Histidine Rich Protein II (HRPII) and Blood Coagulation
Oct 16, 2009 Effect of Malarial Histidine-rich Protein II (HRPII) on Blood Coagulation
Oct 15, 2010 Interaction of TFPI with Factor V
Oct 14, 2011 Studies on Lipoprotein-free and Lipoprotein-associated Plasma Tissue Factor Pathway Inhibitor
Nesheim, Mike Apr 19, 1996 Isolation, Characterization, and Thrombin-thrombomodulin Dependent Activation of TAFI
Neufeld, Elizabeth Oct 31, 2008 1st Rosalind Kornfeld Lecture: Four Decades of Research on MPS
Niero, Evandro Mar 2, 2017 Teleomere Shortening Impairs Hepatocyte Differentiation by DNA Damage Signaling Activation
Nolta, Jan Jan 30, 2004 Immune Deficient Mouse Models for Studying Human Hematopoietic Stem Cell Biology
Norris, Andy Apr 10, 1998 The Regulation of PI 3-Kinase Signaling by Inositol Polyphosphate 4-Phosphatases
Novack, Deb Jan 10, 2014 NIK’ing the Bone: Mechanisms for Control of the Osteoclast
O
O'Shea, Erin Sep 10, 2010 3rd Rosalind Kornfeld Lecture: Translating DNA Sequence Into Gene Expression Output
Odom, Audrey Oct 23, 2009 Essential Isoprenoids in Plasmodium Falciparum Malaria
Oh, Steve May 20, 2011 The Missing LNK: Mechanisms of Dysregulated Signaling in Myeloproliferative Neoplasms
May 18, 2012 JAK2 and Beyond: Genomics and Signaling in Myeloproliferative Neoplasms
Mar 29, 2013 Towards an Understanding of Genetic and Phenotypic Complexity in Myeloproliferative Neoplasms
Orkin, Stuart Nov 11, 1994 22nd Carl Moore Lecture: Multi-layered Regulation of Hematopoietic Development and Transcription
Orlowski, Rachel Mar 27, 2009 Studies with Protein O-fucosyltransferase 2
Ornitz, Dave Oct 7, 1994 Regulation of FGF/FGF Receptor Activity
Apr 19, 2002 FGF and FGF Receptor Signaling in Skeletal Development and Genetic Disease
Ory, Dan Nov 20, 2009 The Niemann-Pick C Pathway: a Key Regulator of Cholesterol Homeostasis
P
Parks, Bill Jan 16, 2004 Extracellular Proteolysis in Epithelial Repair and Defense
Payton, Jackie Oct 18, 2013 Targeting the Malignant Epigenome in B Cell Lymphoma
Permutt, Alan Feb 28, 1997 Genetic Analysis of Monogenic and Polygenic Disorders of Glucose Metabolism
Pham, Christine Dec 16, 2005 Neutrophil Serine Proteases: Specific Regulatory Effectors of Immunity
Pike, Linda May 2, 2003 EGF Receptors and Lipid Rafts: Bringing Order to Chaos
Jan 15, 2010 Bi-Directional Signaling in the EGF Receptor
Piwnica-Worms, David May 5, 2000 Molecular Imaging: Functional Identification of MDR1 Pgp Transport Activity in Tumors and Tissues in Vivo
Piwnica-Worms, Helen May 2, 1997 Reversible Phosphorylation and Cell Cycle Control
Sep 26, 2003 Cell Cycle- and Checkpoint-Control: the CHK1/CDC25A Regulatory Pathway
Feb 11, 2011 Translation of Fundamental Cell Cycle Principles to Targeted Cancer Therapies
Ponder, Kathy Dec 13, 1996 Gene Therapy for Plasma Protein Deficiencies
Mar 12, 1999 Hepatic Gene Therapy for Plasma Protein Deficiencies and Lysosomal Storage Diseases
Feb 2, 2001 Degradation of Hepatocyte Nuclear Factor 4 Contributes to Liver Failure
May 9, 2003 Liver-Directed Gene Therapy Corrects Hemophilia B and Mucopolysaccharidosis VII in Dogs
Jan 28, 2005 Reducing Immune Responses After Gene Therapy for Genetic Diseases
Nov 17, 2006 Gene Therapy for Mucopolysaccharidosis
Jan 23, 2009 The Pathogenesis of Disease in Mucopolysaccharidosis
Apr 22, 2011 The Pathogenesis of Mucopolysaccharidosis May Involve Complement Activation
Apr 12, 2013 The Effect of Gene Therapy for Mucopolysaccharidosis After a Decade
May 22, 2015 Central Nervous System-Directed Gene Therapy for Mucopolysaccharidosis VII
Pratt, Steve Jan 21, 2005 Work-in-Progress
Prescott, Steve Sep 19, 2014 Phil Majerus Symposium: Lipid Messengers: I Met Them in St. Louis
Preston, Roger Oct 18, 2012 Regulating the Regulator: Modulating Activated Protein C Functions for Therapeutic Gain
Prusiner, Stanley Nov 5, 1993 21st Carl Moore Lecture: Transgenetic and Protein Structural Approaches to Unraveling the Enigmas of Prion Diseases
Purvis, Angie Jan 7, 2005 Work-in-Progress
Apr 14, 2006 Work-in-Progress
May 4, 2007 Identification of Cysteine Residues Essential for von Willebrand Factor (VWF) Multimerization: an Elephant is Born
Apr 11, 2008 Von Willebrand Factor: the Free Thiol Saga Continues
Feb 13, 2009 pH Dependence of VWF Multimerization and Storage
Q
Qian, Monica Jan 22, 2010 Functions of the α, β and γ Subunits of UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-Phosphotransferase
Dec 17, 2010 UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-Phosphotransferase
Dec 16, 2011 Functions of the α, β and γ Subunits of UDP-G1cNAc:Lysosomal Enzyme N-acetylglucosamine-1-phosphotransferase
Oct 26, 2012 Missense Mutations in Mucolipidosis II and Mucolipidosis III
Nov 8, 2013 Analysis of Mutations in MLII and MLIII α/β Patients - a New Way to Study Lysosomal Enzyme Sorting
R
Ramsingh, Giri May 15, 2009 Characterizing MicroRNAs in Acute Myeloid Leukemia
Randi, Anna Apr 26, 2013 Von Willebrand Factor Regulates Angiogenesis and Endothelial Progenitors' Function
Ratner, Lee Jan 28, 2000 Human T-Cell Leukemia Virus Tax, Transactivation, and Transformation
Jan 11, 2008 T-Cell Activation and Lymphoma
Razani, Babak Apr 6, 2017 Macrophages Epitomize Firefighter Arsonists in Metabolic Diseases. Can We Promote Better Behavior?
May 6, 2021 Dietary Protein and Amino Acid-Mediated mTOR Signaling in Atherosclerosis
Richardson, Chris Apr 4, 2018 The Fanconi Anemia Pathway Plays a Key Role in DNA Repair at CRISPR-Cas9 Cut Sites
Ricketts, Lindsay Jan 12, 2007 O-fucosylation of ADAMTS13
Riehl, Terry Nov 12, 2010 COX-1+/-COX-2-/- Genotype in Mice is Associated with Shortened Time to Carotid Artery Occlusion Through Increased PAI-1
Robledo, Sara Apr 13, 2007 The Role of Ribosomal Proteins in the Pathogenesis of Diamond Blackfan Anemia
Mar 14, 2008 The Role of Human Ribosomal Proteins in the Maturation of rRNA and Ribosome Production
Rohrer, Jack Dec 15, 1995 Sorting of Proteins in the Endosomal/Lysosomal System
Rondina, Matthew Jan 31, 2020 Platelet Transcriptomics as Discovery Tools in Human Health and Disease
Rosenfeld, Michael Dec 8, 1995 23rd Carl Moore Lecture: Transcriptional Mechanisms of Organ Commitment
Rowley, Janet Oct 10, 2003 31st Carl Moore Lecture: New Paradigms From Leukemias
Ruggeri, Zaverio Sep 30, 1994 Mechanisms of Initiation of Platelet Thrombus Formation
Russler-Germain, David Apr 24, 2015 Molecular Consequences of DNMT3A Mutations in AML
Feb 25, 2021 Novel Mutations Contributing to Follicular Lymphoma
S
Sabatini, David Nov 21, 2014 42nd Carl Moore Lecture: Regulation of Growth by the mTOR Pathway
Sadler, Evan Feb 21, 1997 Thrombin Structure and Biological Function
Jan 22, 1999 Enteropeptidase, Initiator of a Digestive Protease Cascade
Jan 12, 2001 Structure and Function of Von Willebrand Factor
Sep 27, 2002 Von Willebrand Factor, ADAMTS13, and Thrombotic Thrombocytopenic Purpura
Feb 11, 2005 Von Willebrand Factor, Bleeding, and Thrombosis
Feb 16, 2007 Von Willebrand Factor, ADAMTS13, and the Regulation of Platelet Adhesion
Feb 6, 2009 Assembly and Destruction of Von Willebrand Factor
Jan 13, 2012 Von Willebrand Factor, ADAMTS13, and Thrombotic Microangiopathy
Jan 18, 2013 Assembly and Destruction of Von Willebrand Factor
Jan 9, 2015 Von Willebrand Factor, ADAMTS13 and Thrombotic Microangiopathy
Saffitz, Jeff Feb 27, 2004 Mechanisms of Sudden Death in Cardiomyopathies Caused by Mutations in Cell-Cell Junction Proteins
Salvesen, Guy Sep 24, 1993 Inhibition of IL-1β Activation by a Virally Encoded Proteinase Inhibitor
Sands, Mark Oct 29, 1993 Molecular Characterization of the Genetic Defect and Modes of Treatment in Murine Mucopolysaccharidosis Type 7
Nov 5, 1999 Gene Therapy for Lysosomal Storage Diseases
Apr 4, 2003 Hematopoietic-Directed Therapies for Lysosomal Storage Diseases
Mar 12, 2010 Lysosomal Dysfunction Results in Altered Energy Balance
Sanfilippo, Kristen Feb 8, 2013 Thrombosis in Myeloma
Feb 14, 2014 Zoledronic Acid Versus Pamidronate in Patients with Multiple Myeloma: a Comparative Effectiveness Research Project
Apr 21, 2016 Statin Therapy Increases Survival in Myeloma
Santoro, Sam Mar 11, 1994 Structure, Function and Regulation of the α2β1 Integrin
Feb 11, 2000 Collagen Receptors: From Ligand Binding to Control of Cell Phenotype
Sarma, Nayan Feb 27, 2009 Molecular Interactions of the Oncogene Nup98-HoxA9
Saunders, Scott Oct 7, 2005 Heparan Sulfate Proteoglycans: Essential Modulators of Cellular Functions at the Plasma Membrane
Savage, Sharon Nov 12, 2020 The Growing Clinical and Genetic Spectrum of Telomere Biology Disorders
Schaffer, Jean May 3, 2002 Models and Mechanisms of Lipotoxicity
Schmid, Sandra Oct 24, 2014 7th Rosalind Kornfeld Lecture: Dynamin: The Master Regulator of Clathrin-Mediated Endocytosis
Schroeder, Mark Apr 10, 2009 Graft Versus Host Disease: a Novel Mouse Model and Therapy
Feb 4, 2011 Exploring Cytokines to Treat Graft-vs-Host Disease
Mar 2, 2012 Mobilization of Allogeniec Sibling Peripheral Blood Stem Cell Donors with GM-CSF and Plerixafor – an Interim Analysis
Searleman, Adam Apr 1, 2011 Determination of In Vivo Signaling Networks Governing Ductal Carcinoma In Situ Progression
Mar 16, 2012 Characterization of a Mouse Model of Ductal Carcinoma In Situ of the Breast
Feb 8, 2013 Mechanisms of Transformation in HER2-Overexpressing Mammary Epithelium
Semenkovich, Clay May 17, 2002 Fatty Acid Metabolism as a Mediator of Vascular Disease and Beta Cell Failure in Diabetes
Feb 24, 2012 Lipogenesis: Much More Than Making Fat
Sfeir, Agnel Feb 22, 2018 Protecting Our Genomes: Whenever, Wherever
Shafer, Jules Nov 2, 1993 Identification of Amino Acid Residues Important for the Heparin-Catalyzed Inactivation of Thrombin by Antithrombin III
Shah, Dhvanit Feb 14, 2013 Genetic Screen to Identify Genes Regulating Hematopoiesis
Shaw, Andrey Feb 8, 2002 Immunological Synapses and T Cell Signaling
Feb 10, 2006 Macropinocytosis and Nephrotic Syndrome
Sheehan, John Mar 17, 1995 Molecular Mechanism of Thrombin Regulation
Jun 3, 2019 Plasma Factor IXa in Systemic Hypercoagulability
Shen, Bo Mar 2, 2021 Novel Regulators of Bone Marrow Stem Cells: Growth and Mechanical Force
Sherr, Chuck Nov 12, 2004 32nd Carl Moore Lecture: INK4a-ARF: A Marriage of Tumor Suppressors
Shim, Kyuhwan Apr 1, 2005 Work-in-Progress
Nov 10, 2006 Platelet-VWF Complexes are Preferred Substrates of ADAMTS13 Under Fluid Shear Stress
Oct 12, 2007 Platelet-von Willebrand Factor Complexes Are Preferred Substrates of ADAMTS13 Under Fluid Shear Stress
Shivdasani, Ramesh Sep 15, 1995 Transcriptional Control of Cell Fate Determination and Differentiation in Hematopoiesis: Lessons From Knockout Mice
Shulman, Gerald Nov 6, 2009 37th Carl Moore Lecture: Cellular Mechanisms of Insulin Resistance: Implications for Obesity, Lipodystrophy, Metabolic Syndrome and Type 2 Diabetes
Simon, Celeste Nov 18, 1994 Analysis of Hematopoiesis From the Study of Mutant Mice
Sly, Bill Jun 5, 1998 Mutations in HFE Protein Cause Hemochromatosis
Jan 27, 2006 Functional Genomics of Carbonic Anhydrases: From Osteopetrosis to Protein Folding Diseases
Snyder, Steve Mar 10, 2016 Mechanisms of Dysregulated Signaling in Mouse Models of Myeloproliferative Neoplasms
Oct 27, 2016 The Role of NFκB in MPN Mouse Models
Nov 16, 2017 Exploring the Role of NFκB in PMN Mouse Models
Sood Gupta, Deepti Jan 17, 2019 A Novel SPIC/BCLAF1 Complex Reprograms PU.1 Activity in Pre-B Cells With Rag-Mediated DNA Breaks
Stamatoyannopoulos, John Oct 14, 2016 44th Carl Moore Lecture: Decoding the Human Regulatory Genome
Stanley, Sam Oct 15, 1999 Pathways for Amebic Induction of Inflammation and Programmed Cell Death
Steet, Rich Nov 19, 2004 COG7 Deficiency: a Novel Congenital Disorder of Glycosylation
May 13, 2005 Work-in-Progress
Jan 6, 2006 Work-in-Progress
Steitz, Joan Oct 30, 2009 2nd Rosalind Kornfeld Lecture: Regulating the Activity of MicroRNAs in Vertebrate Cells
Stenson, Bill Sep 2, 2005 Prostaglandins and the Epithelial Response to Radiation Injury
Stewart, Sheila Mar 24, 2006 The Yin and Yang of Cellular Senescence
Stoddard, Barry Oct 17, 2006 The Structure of Human Factor VIII and Its Inhibition Via Mutations, Antibodies, and Small Molecules
Storch, Greg Mar 7, 2014 Virologic, Genomic, and Transcriptomic Analysis of Fever Without a Source in Young Children
Sturgeon, Chris Apr 11, 2013 Modeling Developmental Hematopoiesis Using Pluripotent Stem Cells
Feb 20, 2015 Modeling Developmental Hematopoiesis Using Pluripotent Stem Cells
Sullivan, Ryan Sep 30, 2011 MicroRNA Deficient Natural Killer Cells Exhibit Decreased Survival but Enhanced Cytokine Production and Degranulation Capacity
Sep 28, 2012 The Role of miR-155 in Natural Killer Cell Function
Sep 20, 2013 MiR-15/16 Antagonizes Myb to Control Natural Killer Cell Differentiation and Maturation
Sykes, David Feb 6, 2017 "Curing by Maturing" - Developing Differentiation Therapy for the Treatment of Patients with Acute Myeloid Leukemia
T
Tamai, Minori Apr 25, 2019 Modeling Infant Leukemia With Human Pluripotent Stem Cells
Taniguchi, Naoyuki Sep 12, 1994 Transfection of N-Acetylglucosaminyltransferase III Gene Into Melanomas Suppresses Lung Metastasis
Tarr, Phil Sep 29, 2006 Escherichia Coli O157:H7 and the Hemolytic Uremic Syndrome: Host and Microbial Aspects
Taylor, James Jan 15, 2016 Epidemiologic and Mechanistic Insights into Risk Factors for Death in Adults with Sickle Cell Anemia
Teitelbaum, Steve Sep 14, 2001 RANK Ligand and Bone Cells
Thomas, Matt Jan 23, 1998 The Regulation of Adhesion and Signal Transduction by Protein Tyrosine Phosphatases
Thompson, Craig Oct 20, 2006 34th Carl Moore Lecture: Programmed Cell Death: Apoptosis, Autophagy, and Necrosis
Tittiger, Mindy May 11, 2007 Parallels in Mucopolysaccharidosis (MPS) I and MPS 7 Aortic Disease
Tollefsen, Doug Jan 24, 1997 The Two Faces of Thrombin: Interactions of Exosites I and II With Inhibitors
Feb 12, 1999 Allosteric Regulation of Thrombin by a Monoclonal Antibody That Binds to Exosite II
Feb 9, 2001 Function of Heparin Cofactor II in Vitro and in Vivo
Apr 18, 2003 Heparin Cofactor II and Thrombosis
Feb 25, 2005 Activation of Heparin Cofactor II by Vascular Glycosaminoglycans
Jan 5, 2007 Heparin Cofactor II Modulates the Response to Arterial Injury
Mar 20, 2009 TAP-Annexin V: a Novel Antithrombotic Agent
Oct 22, 2010 Activation of Heparin Cofactor II by Arterial Dermatan Sulfate
Tomasson, Michael Oct 12, 2001 The Role of Fusion Oncogenes in the Multi-Step Pathogenesis of Acute Leukemia
Sep 21, 2007 Genetic Progression Factors in Leukemia: One Good Mutation Deserves Another
May 10, 2013 The Role of Orphan SnoRNA ACA11 in the Pathogenesis of T(4;14)-Positive Multiple Myeloma
Towler, Dwight Mar 13, 1998 Structure-Function Analysis of Msx2-Mediated Transcriptional Suppression: Promoter Repression Via RAP74 and the FGF Response Element DNA Binding Protein
Tran, David Apr 1, 2011 The Snail1-Twist1 Cooperation in EMT Maintenance and Cancer Dormancy
Traub, Linton Oct 28, 1994 Clathrin-Coated Vesicle Assembly on the Golgi
Jan 8, 1999 Lysosomes, Liposomes and Synaptosomes: What Do They Teach Us About Clathrin-Coat Assembly?
Trissal, Maria May 13, 2011 Role of Small Non-coding RNAs in Normal and Malignant Hematopoiesis
Apr 13, 2012 Small Non Coding RNAs in Normal and Malignant Hematopoiesis
Apr 5, 2013 Dysregulation of the Imprinted DLK1-DIO3 Locus in Promyelocytic Leukemia
Jan 17, 2014 Dysregulation and Recurrent Mutation of miRNA-142 in Acute Myeloid Leukemia
Trompouki, Eirini Feb 7, 2013 From Zebrafish to Man: BMP and Wnt Signaling Pathways in Normal and Stress Hematopoiesis
Tsai, Schickwann Nov 10, 1995 Developmental Control of Hematopoietic Stem Cells and Progenitors by Retinoic Acid Receptors
Tyagi, Garima Gupta Mar 14, 2014 Interactions Between VWF and ADAMTS13 (Catalytic and Non-catalytic)
Feb 11, 2016 Single Molecule Analysis of Von Willebrand Factor Extension and Cleavage Using Magnetic Tweezers
Jan 19, 2017 Single Molecule Analysis of VWF Extension and Cleavage Using Magnetic Tweezers
Mar 22, 2018 Single Molecule Analysis of VWF Extension and Cleavage Using Magnetic Tweezers
U
Ungewickell, Alex Feb 18, 2005 Work-in-Progress
Nov 18, 2005 Work-in-Progress
V
Vagelos, Roy Sep 19, 2014 Phil Majerus Symposium: Phil, Science, and Medicine
van Meel, Eline Oct 14, 2011 Discovery of the First Disease Causing Mutations in Methionyl-tRNA Synthetase (MARS)
Sep 14, 2012 Mannose 6-Phosphate Independent Lysosomal Targeting of Acid alpha-Glucosidase
Oct 25, 2013 Mislocalization of Phosphotransferase as a Cause of Mucolipidosis III alpha/beta
Oct 17, 2014 Analysis of Mucolipidosis II/III GNPTAB Missense Mutations Identifies Domains of GlcNAc-1-Phosphotransferase Involved in Catalytic Function and Lysosomal Enzyme Recognition
Van Tine, Brian Jan 7, 2011 Taspase1 and HER2+ Breast Cancer
Varki, Ajit Oct 25, 2002 Multiple Differences in Sialic Acid Biology Between Humans and Great Apes
May 6, 2005 Selectins and Cancer: Mechanistic Connections and Therapeutic Implications
Nov 18, 2011 39th Carl Moore Lecture: Adventures in Anthropogeny: From Sialic Acids to Human Uniqueness
Varticovski, Lyuba Oct 1, 1999 Angiopoietins: Signal Transduction and Regulation of Endothelial Cell Biology
Verdoni, Angela Dec 2, 2011 Understanding the Role of DNA Methyltransferase 3A Mutations in Acute Myeloid Leukemia Pathogenesis
Oct 12, 2012 Understanding the Role of DNMT3A Mutations in AML Pathogenesis
Jan 17, 2014 Understanding the Role of the DNMT3A R882H Mutation in AML Pathogenesis
Vessoni, Alex Jan 19, 2017 Impact of Telomere Shortening on Mitochondria of Human Embryonic Stem Cells
Mar 15, 2018 Investigating Cell Death and DNA Damage Response in hESCs With Short Telomeres
Mar 28, 2019 Telomere Dysfunction and Oncogene Stress Induces Differential Responses in Human Embryonic Stem Cells
Sep 19, 2019 DNA Damage Response in Human Embryonic Stem Cells With Short Telomeres
Oct 22, 2020 Investigating the Consequences of Telomere Dysfunction in Human Stem Cells
Viatour, Patrick Sep 15, 2016 E2f Factors Integrate Cell Cycle and Non Cell Cycle Functions to Dictate Stem Cell Fate
Vicente, Cristina Mar 4, 2005 Work-in-Progress
Vindigni, Alessandro Mar 9, 2017 Mechanisms of Replication Stress Response to Chemotherapeutics
Virgin, Skip Dec 12, 1997 Interplay Between Herpesviruses and the Immune System
Apr 23, 2004 Learning From Growth of an Ungrowable Virus
Vomund, Tony Jan 18, 2008 The Interaction of ADAMTS13 and Endothelial Cells
Nov 14, 2008 Characterizing the Interaction Between ADAMTS13 and Endothelial Cells
W
Wagner, Julia Feb 16, 2017 CD56bright NK Cells Exhibit Potent Anti-Tumor Responses Following IL-15 Priming
Nov 16, 2017 Impact of Inducible Eomes Deletion on the Murine NK Cell Compartment
Feb 14, 2019 A Novel NK Cell-Specific Inducible Cre Model Reveals a Critical Role for Eomes in the Survival, Homeostasis, and Function of Mature NK Cells
Walter, Matt Feb 23, 2007 Myelodysplastic Syndrome and Deletions of Chromosome 5q31.2
Wang, Beth May 15, 2015 Transcriptional Regulation of Human Primitive and Definitive Hematopoietic Progenitor Specification
Ward, Jeff Apr 10, 2015 High-Throughput Identification of Tumor Neoantigen-Specific Cytotoxic T-Cells
Feb 25, 2016 Identification and Therapeutic Targeting of Tumor Specific Mutant Antigens
Ward, Michael Mar 4, 2005 Work-in-Progress
Warner, Steve Feb 1, 2008 A Glance at the In Vivo Function of Rho GTPases Through the Fly Eye
Wartman, Lukas Apr 29, 2005 Work-in-Progress
Oct 1, 2010 Conserved Progression Mutations in Mouse and Human Leukemia Genomes
Weber, Jason Nov 4, 2005 Interpretation of Oncogenic Signals by the Nucleolus
Feb 22, 2008 Regulating MRNA Translation Programs in Cancer
Weilbaecher, Kathy Nov 30, 2001 The Role of Beta 3 Integrin in Metastasis
Oct 19, 2007 CXCR4 Regulation of Osteoclast Development and Tumor Osteolysis
Feb 26, 2010 Hedgehog Signaling in Osteoclasts and Bone Metastasis
Mar 8, 2013 Targeting Beta3 Integrin Pathway Genes to Treat Cancer
Welch, John Oct 5, 2012 The Origin and Evolution of AML Mutations
Wente, Susan Feb 17, 1995 Nucleocytoplasmic Trafficking: Insights From Yeast Nuclear Pore Complex Mutants
Feb 23, 2001 Nuclear Entry and Exit: the Rules and the Players
Nov 2, 2012 5th Rosalind Kornfeld Lecture: Beyond the Pore: From Nuclear MRNA Export to Translation
Wilson, Dave Mar 28, 1997 GATA-Binding Proteins and Cardiovascular Development
Sep 8, 2000 Blood and Guts: Erythroid Transcription Factors and Endodermal Development
Mar 15, 2013 Adrenocortical Development and Tumorigenesis: the Saga of Rosie
Wilson, Mo May 4, 2001 A Promiscuous Inositol Kinase
Sep 8, 2006 What the Structure of an Inositol Kinase Tells Us About Its Function
Sep 26, 2008 Neural Tube Defects in Mice With Aberrant Inositol Metabolism
Sep 24, 2010 A Mouse Model Linking Aberrant Inositol Metabolism to Defects in Neural Development
Sep 21, 2012 ITPK1: an Inositol Kinase Linked to Neural Tube Defects
Nov 7, 2014 The Many Roles of ITPK1, an Inositol Kinase
Witte, Owen Dec 11, 1998 26th Carl Moore Lecture: Hematolymphoid Signal Transduction by Cytoplasmic Tyrosine Kinases
Wolf, Beni Jan 22, 2002 Evasion of Mitochondria-Dependent Apoptosis by Cancer Cells
Wong, Pamela Oct 8, 2020 The Role of T-box Transcription Factors Eomes and Tbet in Mature Human Natural Killer Cells
Wong, Terrence Jan 25, 2013 The Genetics of Therapy-related AML
Feb 28, 2014 The Role of TP53 Mutations in the Origin and Evolution of Therapy-Related AML
Oct 31, 2014 The Role of Early TP53 Mutations in the Origin and Evolution of Therapy-Related AML
Oct 1, 2015 Non-Malignant Oligoclonal Hematopoiesis Commonly Follows Induction Chemotherapy for Adult De Novo AML
Jan 18, 2018 Clonal Evolution of Hematopoietic Stem Cells During Chemotherapy and Transplantation
Wu, Gregory Mar 17, 2016 The Role of B Cell Antigen Presentation in a Murine Autoimmune Model of Multiple Sclerosis
Wu, Qingyu Jan 27, 1995 Studies of Thrombin: Mutagenesis and Gene Targeting
X
Xu, Lingfei Mar 18, 2005 Work-in-Progress
Y
Yao, Juo-Chin Robin Oct 7, 2021 TGF-β Signaling in Stromal Cells Contributes to Myelofibrosis, but Not Niche Disruption, in MPNs Throught JNK Activation
Yien, Yvette Feb 16, 2016 Mitochondrial Transporters in Erythroid Heme Metabolism
Yokoyama, Wayne May 16, 1997 The Emerging Spectrum of NK Cell Receptors
Yoo, Andrew Jan 24, 2014 Control of Neuronal Subtype Specificity During MicroRNA-Mediated Neuronal Reprogramming
York, John Jan 26, 2001 Insights Into the Biology of Inositol Signaling
Oct 6, 2006 Signaling Specificity: Inositol Polyphosphate Messengers Regulate Drosophila Development
Sep 14, 2011 Interdisciplinary Seminar Series: Inositol Phosphate Communication: Insights Into the Cell's 'iPhone'
Sep 19, 2014 Phil Majerus Symposium: Insights into Inositol Phosphate Cellular Signaling Pathways
Young, Margaret Feb 18, 2011 Whole Genome Sequencing of Murine Induced Pluripotent Stem Cells
Sep 30, 2011 Canonical and Non-canonical HOX Expression Patterns in Acute Myelogenous Leukemia
Yu, Jeff May 11, 2007 Investigation of the Biological Function of the C-terminal Domains in ADAMTS13
Yu, Zheyong Feb 1, 2008 Modulation of ADAMTS13 Activity by Free Amino Acids
Z
Zaher, Hani Nov 3, 2016 Insights Into the Role of the Ribosome During mRNA and Nascent-Protein Quality Control
Zhang, Chunfen Mar 27, 2009 Identification of Lysine Acetylation Sites on Inositol 1,3,4-Trisphosphate 5/6-Kinase
Apr 23, 2010 Lysine Acetylation of Inositol 1,3,4-Trisphosphate 5/6-kinase
Apr 29, 2011 Lysine Acetylation of Inositol 1,3,4-Trisphosphate 5/6 Kinase
Apr 13, 2012 The role of Myotubularin-related Phosphatases MTMR8 and MTMR9 in the Control of Autophagy
Zhang, Lijuan Sep 23, 2005 Heparan and Chondroitin Sulfate Glycosaminoglycans: a Journey From Structure to Function
Zhang, Lingbo Mar 16, 2021 Understanding and Targeting Hematopoietic Stem and Progenitor Cells
Zhan, Huichun Aug 3, 2017 The Hematopoietic Niche in Myeloproliferative Neoplasms
Zho, Jun Jan 19, 2007 The Role of Type I PIP2 4-phosphatase in Stress Signaling
Zhu, Jian Mar 18, 2011 Structural and Functional Study of ADAMTS13
Mar 30, 2012 Small-angle X-ray Scattering Studies of ADAMTS13 Demonstrate a Conformational Response to Substrate Binding in Solution
Mar 22, 2013 Regulation of ADAMTS13 Activity
May 9, 2014 Structural Studies of ADAMTS13 Using Small-angle X-ray Scattering
May 8, 2015 A Folded ADAMTS13 Conformation Identified by SAXS Can Account for Allosteric Regulation by Distal TSP and CUB Domains
Mar 10, 2016 Study of Allosteric Regulation of ADAMTS13 by Small-Angle X-Ray Scattering
Feb 2, 2017 The Hunt for the "Minimal" Structure of a Functional ADAMTS13 by Small-Angle X-Ray Scattering
Jan 11, 2018 Structural and Functional Studies of ADAMTS13: AUC, HDX, and EM
Zimmerman, Megan Dec 13, 2018 MDM2 Inhibition in T-Cell Acute Lymphoblastic Leukemia
Zou, Jun Nov 9, 2007 Type I Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Regulates Stress-induced Apoptosis
Jan 16, 2009 MTMR9 Increases MTMR6 Enzyme Activity, Stability, and Has a Role in Apoptosis
Apr 23, 2010 Characterization of Myotubularin Related Protein 8
Zutter, Mary Feb 14, 2003 The α2β1-Integrin Deficient Mouse: Defective Platelet and Mast Cell Function