Faculty
Oncology Division
Alphabetical list (active faculty):   
Vivek K. Arora

Vivek K. Arora, MD, PhD

Assistant Professor

Department of Medicine

Oncology Division

Molecular Oncology

Contact

  • 314-454-8681 (office)
  • 314-747-2797 (fax)
  • Division of Oncology
    Campus Box 8069
    Washington University
    660 South Euclid Avenue
    St. Louis, MO 63110
  • 8th Floor, McDonnell Sciences Building (office)

Original Articles

  • Urine Tumor DNA Detection of Minimal Residual Disease in Muscle-Invasive Bladder Cancer Treated With Curative-Intent Radical Cystectomy: A Cohort Study
    Chauhan PS, Chen K, Babbra RK, Feng W, Pejovic N, Nallicheri A, Harris PK, Dienstbach K, Atkocius A, Maguire L, Qaium F, Szymanski JJ, Baumann BC, Ding L, Cao D, Reimers MA, Kim EH, Smith ZL, Arora VK, Chaudhuri AA
    PLoS Med 2021 Aug 31;18(8):e1003732
  • A Randomized Phase II Study of Androgen Deprivation Therapy With or Without Palbociclib in RB-Positive Metastatic Hormone-Sensitive Prostate Cancer
    Palmbos PL, Daignault-Newton S, Tomlins SA, Agarwal N, Twardowski P, Morgans AK, Kelly WK, Arora VK, Antonarakis ES, Siddiqui J, Jacobson JA, Davenport MS, Robinson DR, Chinnaiyan AM, Knudsen KE, Hussain M
    Clin Cancer Res 2021 Jun 1;27(11):3017-3027
  • Management of Muscle-Invasive Bladder Cancer During a Pandemic: Impact of Treatment Delay on Survival Outcomes for Patients Treated With Definitive Concurrent Chemoradiotherapy
    Fischer-Valuck BW, Michalski JM, Harton JG, Birtle A, Christodouleas JP, Efstathiou JA, Arora VK, Kim EH, Knoche EM, Pachynski RK, Picus J, Rao YJ, Reimers M, Roth BJ, Sargos P, Smith ZL, Zaghloul MS, Gay HA, Patel SA, Baumann BC
    Clin Genitourin Cancer 2021 Feb;19(1):41-46
  • Emerging Roles of Urine-Based Tumor DNA Analysis in Bladder Cancer Management
    Chaudhuri AA, Pellini B, Pejovic N, Chauhan PS, Harris PK, Szymanski JJ, Smith ZL, Arora VK
    JCO Precis Oncol 2020 Jul 15;4
  • Effectiveness of Postoperative Radiotherapy After Radical Cystectomy for Locally Advanced Bladder Cancer
    Fischer-Valuck BW, Michalski JM, Mitra N, Christodouleas JP, DeWees TA, Kim E, Smith ZL, Andriole GL, Arora VK, Bullock A, Carmona R, Figenshau RS, Grubb RL, Guzzo TJ, Knoche EM, Malkowicz SB, Mamtani R, Pachynski RK, Roth BJ, Zaghloul MS, Gay HA, Baumann BC
    Cancer Med 2019 Jul;8(8):3698-3709
  • A Propensity Analysis Comparing Definitive Chemo-Radiotherapy for Muscle-Invasive Squamous Cell Carcinoma of the Bladder Vs. Urothelial Carcinoma of the Bladder Using the National Cancer Database
    Fischer-Valuck BW, Michalski JM, Contreras JA, Brenneman R, Christodouleas JP, Abraham CD, Kim EH, Arora VK, Bullock AD, Carmona R, Figenshau RS, Grubb R 3rd, Knoche EM, Pachynski RK, Picus J, Roth BJ, Sargos P, Andriole GL, Gay HA, Baumann BC
    Clin Transl Radiat Oncol 2018 Dec 12;15:38-41
  • CD4+ T Cells Induce Rejection of Urothelial Tumors After Immune Checkpoint Blockade
    Sato Y, Bolzenius JK, Eteleeb AM, Su X, Maher CA, Sehn JK, Arora VK
    JCI Insight 2018 Dec 6;3(23)
  • Bladder-Cancer-Associated Mutations in RXRA Activate Peroxisome Proliferator-Activated Receptors to Drive Urothelial Proliferation
    Halstead AM, Kapadia CD, Bolzenius J, Chu CE, Schriefer A, Wartman LD, Bowman GR, Arora VK
    Elife 2017 Nov 16;6
  • Regulation of the Glucocorticoid Receptor Via a BET-Dependent Enhancer Drives Antiandrogen Resistance in Prostate Cancer
    Shah N, Wang P, Wongvipat J, Karthaus WR, Abida W, Armenia J, Rockowitz S, Drier Y, Bernstein BE, Long HW, Freedman ML, Arora VK, Zheng D, Sawyers CL
    Elife 2017 Sep 11;6
  • Organoid Cultures Derived From Patients With Advanced Prostate Cancer
    Gao D, Vela I, Sboner A, Iaquinta PJ, Karthaus WR, Gopalan A, Dowling C, Wanjala JN, Undvall EA, Arora VK, Wongvipat J, Kossai M, Ramazanoglu S, Barboza LP, Di W, Cao Z, Zhang QF, Sirota I, Ran L, MacDonald TY, Beltran H, Mosquera JM, Touijer KA, Scardino PT, Laudone VP, Curtis KR, Rathkopf DE, Morris MJ, Danila DC, Slovin SF, Solomon SB, Eastham JA, Chi P, Carver B, Rubin MA, Scher HI, Clevers H, Sawyers CL, Chen Y
    Cell 2014 Sep 25;159(1):176-87
  • Aggressive Variants of Castration-Resistant Prostate Cancer
    Beltran H, Tomlins S, Aparicio A, Arora V, Rickman D, Ayala G, Huang J, True L, Gleave ME, Soule H, Logothetis C, Rubin MA
    Clin Cancer Res 2014 Jun 1;20(11):2846-50
  • Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
    Arora VK, Schenkein E, Murali R, Subudhi SK, Wongvipat J, Balbas MD, Shah N, Cai L, Efstathiou E, Logothetis C, Zheng D, Sawyers CL
    Cell 2013 Dec 5;155(6):1309-22
  • Androgen Receptor Signaling Regulates DNA Repair in Prostate Cancers
    Polkinghorn WR, Parker JS, Lee MX, Kass EM, Spratt DE, Iaquinta PJ, Arora VK, Yen WF, Cai L, Zheng D, Carver BS, Chen Y, Watson PA, Shah NP, Fujisawa S, Goglia AG, Gopalan A, Hieronymus H, Wongvipat J, Scardino PT, Zelefsky MJ, Jasin M, Chaudhuri J, Powell SN, Sawyers CL
    Cancer Discov 2013 Nov;3(11):1245-53
  • Overcoming Mutation-Based Resistance to Antiandrogens With Rational Drug Design
    Balbas MD, Evans MJ, Hosfield DJ, Wongvipat J, Arora VK, Watson PA, Chen Y, Greene GL, Shen Y, Sawyers CL
    Elife 2013 Apr 9;2:e00499
  • ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment
    Clegg NJ, Wongvipat J, Joseph JD, Tran C, Ouk S, Dilhas A, Chen Y, Grillot K, Bischoff ED, Cai L, Aparicio A, Dorow S, Arora V, Shao G, Qian J, Zhao H, Yang G, Cao C, Sensintaffar J, Wasielewska T, Herbert MR, Bonnefous C, Darimont B, Scher HI, Smith-Jones P, Klang M, Smith ND, De Stanchina E, Wu N, Ouerfelli O, Rix PJ, Heyman RA, Jung ME, Sawyers CL, Hager JH
    Cancer Res 2012 Mar 15;72(6):1494-503
  • Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer
    Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, Arora VK, Le C, Koutcher J, Scher H, Scardino PT, Rosen N, Sawyers CL
    Cancer Cell 2011 May 17;19(5):575-86
  • Integrative Genomic Profiling of Human Prostate Cancer
    Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, Arora VK, Kaushik P, Cerami E, Reva B, Antipin Y, Mitsiades N, Landers T, Dolgalev I, Major JE, Wilson M, Socci ND, Lash AE, Heguy A, Eastham JA, Scher HI, Reuter VE, Scardino PT, Sander C, Sawyers CL, Gerald WL
    Cancer Cell 2010 Jul 13;18(1):11-22
  • Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
    Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL
    Science 2009 May 8;324(5928):787-90
  • Activation of P21-Activated Kinase 2 by Human Immunodeficiency Virus Type 1 Nef Induces Merlin Phosphorylation
    Wei BL, Arora VK, Raney A, Kuo LS, Xiao GH, O'Neill E, Testa JR, Foster JL, Garcia JV
    J Virol 2005 Dec;79(23):14976-80
  • Genetic and Functional Diversity of Human Immunodeficiency Virus Type 1 Subtype B Nef Primary Isolates
    Foster JL, Molina RP, Luo T, Arora VK, Huang Y, Ho DD, Garcia JV
    J Virol 2001 Feb;75(4):1672-80
  • Lentivirus Nef Specifically Activates Pak2
    Arora VK, Molina RP, Foster JL, Blakemore JL, Chernoff J, Fredericksen BL, Garcia JV
    J Virol 2000 Dec;74(23):11081-7
  • The Third Intracellular Loop of the Rat Gonadotropin-Releasing Hormone Receptor Couples the Receptor to Gs- And G(Q/11)-Mediated Signal Transduction Pathways: Evidence From Loop Fragment Transfection in GGH3 Cells
    Ulloa-Aguirre A, Stanislaus D, Arora V, Vaananen J, Brothers S, Janovick JA, Conn PM
    Endocrinology 1998 May;139(5):2472-8
  • The Cloning of a Caenorhabditis Elegans Guanylyl Cyclase and the Construction of a Ligand-Sensitive Mammalian/Nematode Chimeric Receptor
    Baude EJ, Arora VK, Yu S, Garbers DL, Wedel BJ
    J Biol Chem 1997 Jun 20;272(25):16035-9
  • Biphasic Action of Cyclic Adenosine 3',5'- Monophosphate in Gonadotropin-Releasing Hormone (GnRH) Analog-Stimulated Hormone Release From GH3 Cells Stably Transfected With GnRH Receptor Complementary Deoxyribonucleic Acid
    Stanislaus D, Arora V, Awara WM, Conn PM
    Endocrinology 1996 Mar;137(3):1025-31

Book Chapters and Reviews

  • Bladder Cancer
    Arora VK
    In: The Washington Manual of Oncology, 4th Edition (Morgensztern D, Ghobadi A, Govindan R, Editors), Wolters Kluwer, Philadelphia, 2022
  • Emerging Mechanisms of Resistance to Androgen Receptor Inhibitors in Prostate Cancer
    Watson PA, Arora VK, Sawyers CL
    Nat Rev Cancer 2015 Dec;15(12):701-11
  • Molecular Biology of Prostate Cancer
    Chen Y, Arora VK, Sawyers CL
    In: CANCER: Principles & Practice of Oncology 9th edition
  • Nef: Agent of Cell Subversion
    Arora VK, Fredericksen BL, Garcia JV
    Microbes Infect 2002 Feb;4(2):189-99