Oncology Division

Grant A. Challen, PhD

Associate Professor
Department of Medicine
Oncology Division
Stem Cell Biology

Research Interests

  • Hematopoietic stem cells
  • Leukemia stem cells
  • Epigenetic modifications


  • 314-362-0987 (tel)
  • 314-362-1953 (fax)
  • Room 744 Southwest Tower (lab)
  • Washington University School of Medicine
    Division of Oncology
    Campus Box 8007
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Challen Lab Website


1997-2000 BSc(Hons) in Molecular Biology, Central Queensland University, Rockhampton, QLD, Australia
2002-2006 PhD in Developmental Biology, The University of Queensland, Brisbane, QLD, Australia
(Mentor: Professor Melissa Little)
Post-graduate Training
2006-2012 Post-doctoral Fellow, Baylor College of Medicine, Houston, TX
(Mentor: Professor Margaret Goodell)
Academic Positions
2012-2018 Assistant Professor, Department of Internal Medicine, Washington University, St. Louis, MO
2018-present Associate Professor, Department of Internal Medicine, Washington University, St. Louis, MO
University & Hospital Appointments & Committees
Siteman Cancer Center Member (Hematopoietic Development and Malignancy Program)
Institute of Clinical and Translation Sciences Member
DBBS Member (Developmental, Regenerative and Stem Cell Biology Program; Molecular Cell Biology Program; Molecular Genetics and Genomics Program; Computational and Systems Biology Program)
2016 Washington University Leukemia Spore Scientific Review Committee
2015, 2016,
2018, 2019
Siteman SIP Study Section
2018-present IACUC Commitee Member
2019 BioSURF Program Reviewer
2019-present Pediatric Hematology-Oncology Training Program T32 Steering Committee
Honors & Awards
2010 American Society of Hematology Joanne Levy Memorial Medal
2010 Dan L. Duncan Cancer Center Symposium "Best Oral Presentation"
2010 American Society of Hematology ASH Scholar Award
2010 NIH K99/R00 Career Development Award
2011 Forbeck Scholar Award (William Guy Forbeck Research Foundation)
2012 Alex’s Lemonade Stand "A" Award
2013 Edward Mallinckrodt, Jr. Foundation Scholar
2014 American Society of Hematology ASH Junior Faculty Scholar
2015 Sidney Kimmel Foundation Scholar Award
2015 V Foundation V Scholar Award
2018 Leukemia and Lymphoma Scholar Award
Editorial Responsibilities
2017-present iScience (Cell Press) Editorial Board Member
National Service & Leadership Roles
2016 Connecticut Regenerative Medicine Research Fund (RMRF) Reviewer
2017 NIH scientific Reviewer TAG Study Section (Ad Hoc)
2017, 2019 Edward P. Evans MDS Foundation Scientific Reviewer
2017 Swiss Cancer Foundation Scientific Reviewer
2018, 2019 Kay Kendall Leukemia Fund (KKLF) Scientific Reviewer
2018 Welcome Trust Scientific Reviewer
2018 Biotechnology and Biological Sciences Research Council (BBSRC) Scientific Reviewer
2019 Istituto Pasteur Italia Scientific Reviewer
2019 UK Bloodwise Project GrantReviewer
2019 Netherlands Organization for Health Research and Development Grant Reviewer
2019 Canada Research Chair (CRC) Program Reviewer
2019 Meeting Organizer EvansMDS Summit (St. Louis, MO; October 24-25)
Professional Societies & Organizations
2005-present International Society For Stem Cell Research (ISSCR)
2009-present American Society of Hematology (ASH)
2014-2018: ASH Ad Hoc Scientific Committee on Epigenetics and Genomics (2016 Vice-chair, 2017 Chair)
2014: Abstract review committee, Section 501 (Hematopoietic Stem and Progenitor Cell Biology)
2015: Abstract review committee chair, Section 501 (Hematopoietic Stem and Progenitor Cell Biology)
2018: ASH-a-Palooza Blood Drop Speaker
2012-present Society for Hematology and Stem Cells (ISEH)
2012-2016: ISEH New Investigator Committee
2014-2016: Head of Webinars Subcommittee
2017-present: Publications committee