Grant A. Challen, PhD

Associate Professor
Department of Medicine
Oncology Division
Stem Cell Biology

Research Interests

  • Hematopoietic stem cells
  • Leukemia stem cells
  • Epigenetic modifications


  • 314-362-0987 (tel)
  • 314-362-1953 (fax)
  • Room 744 Southwest Tower (lab)
  • Washington University School of Medicine
    Division of Oncology
    Campus Box 8007
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Challen Lab Website


1997-2000 BSc(Hons) in Molecular Biology, Central Queensland University, Rockhampton, QLD, Australia
2002-2006 PhD in Developmental Biology, The University of Queensland, Brisbane, QLD, Australia
(Mentor: Professor Melissa Little)
Post-graduate Training
2006-2012 Post-doctoral Fellow, Baylor College of Medicine, Houston, TX
(Mentor: Professor Margaret Goodell)
Academic Positions
2012-2018 Assistant Professor, Department of Internal Medicine, Washington University, St. Louis, MO
2018-present Associate Professor, Department of Internal Medicine, Washington University, St. Louis, MO
University & Hospital Appointments & Committees
Siteman Cancer Center member (Hematopoietic Development and Malignancy program)
Institute of Clinical and Translation Sciences member
DBBS member (Developmental, Regenerative and Stem Cell Biology program)
Washington University Leukemia Spore Scientific Review Committee
Siteman SIP Study Section
Honors & Awards
2010 American Society of Hematology Joanne Levy Memorial Medal
2010 Dan L. Duncan Cancer Center Symposium "Best Oral Presentation"
2010 American Society of Hematology ASH Scholar Award
2010 NIH K99/R00 Career Development Award
2011 Forbeck Scholar Award (William Guy Forbeck Research Foundation)
2012 Children's Discovery Institute Interdisciplinary Research Award
2012 Alex’s Lemonade Stand "A" Award
2013 Edward Mallinckrodt, Jr. Foundation Scholar
2013 Selected as WUSM Rita Allen Scholar Award applicant
2014 American Society of Hematology ASH Junior Faculty Scholar
2014 Selected as WUSM Pew Scholar Award applicant
2015 Sidney Kimmel Foundation Scholar Award
2015 V Foundation V Scholar Award
2016 Chair, American Society of Hematology Scientific Committee for Epigenetics and Genomics
2017 Gabrielle’s Angel Foundation Award
Editorial & Review Responsibilities
2016 Connecticut Regenerative Medicine Research Fund (RMRF) reviewer
2017-present iScience (Cell Press) editorial board member
2017 NIH scientific reviewer TAG study section (Ad Hoc)
2017 Edward P. Evans MDS Foundation scientific reviewer
2017 Swiss Cancer Foundation scientific reviewer
2018 Kendall Leukemia Fund scientific reviewer
2018 Welcome Trust scientific reviewer
2018 Biotechnology and Biological Sciences Research Council (BBSRC) scientific reviewer
Professional Societies & Organizations
2005-present International Society For Stem Cell Research (ISSCR)
2009-present American Society of Hematology (ASH)
2014-2018: ASH Ad Hoc Scientific Committee on Epigenetics and Genomics
   2016, Vice-chair
   2017, Chair
2014: Abstract review committee, Section 501 (Hematopoietic Stem and Progenitor Cell Biology)
2015: Abstract review committee chair, Section 501 (Hematopoietic Stem and Progenitor Cell Biology)
2012-present Society for Hematology and Stem Cells (ISEH)
2012-2016: ISEH New Investigator Committee
   2014-2016: Head of Webinars Subcommittee
2017-present: Publications committee