Oncology Division
Alphabetical list (active faculty):   
Matthew L. Cooper

Matthew L. Cooper, PhD

Assistant Professor

Department of Medicine

Oncology Division

Stem Cell Biology


  • 314-273-0142 (office)
  • 314-273-9333 (fax)
  • Division of Oncology
    Campus Box 8056
    Washington University
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Room 626P Southwest Tower (office)

Original Articles

  • Antibody-Drug Conjugates Plus Janus Kinase Inhibitors Enable MHC-Mismatched Allogeneic Hematopoietic Stem Cell Transplantation
    Persaud SP, Ritchey JK, Kim S, Lim S, Ruminski PG, Cooper ML, Rettig MP, Choi J, DiPersio JF
    J Clin Invest 2021 Nov 2; [Epub ahead of print]
  • Boosting and Lassoing New Prostate Cancer SNP Risk Factors and Their Connection to Selenium
    Booth DE, Gopalakrishna-Remani V, Cooper ML, Green FR, Rayman MP
    Sci Rep 2021 Sep 9;11(1):17877
  • CD7-Deleted Hematopoietic Stem Cells Can Restore Immunity After CAR T Cell Therapy
    Kim MY, Cooper ML, Jacobs MT, Ritchey JK, Hollaway J, Fehniger TA, DiPersio JF
    JCI Insight 2021 Aug 23;6(16):e149819
  • Baricitinib Prevents GvHD by Increasing Tregs Via JAK3 and Treats Established GvHD by Promoting Intestinal Tissue Repair Via EGFR
    Kim S, Ashami K, Lim S, Staser K, Vij K, Santhanam S, Ritchey J, Peterson S, Gao F, Ciorba MA, Cooper ML, DiPersio JF, Choi J
    Leukemia 2021 Jul 24; [Epub ahead of print]
  • Multidimensional Analyses of Donor Memory-Like NK Cells Reveal New Associations With Response After Adoptive Immunotherapy for Leukemia
    Berrien-Elliott MM, Cashen AF, Cubitt CC, Neal CC, Wong P, Wagner JA, Foster M, Schappe T, Desai S, McClain E, Becker-Hapak M, Foltz JA, Cooper ML, Jaeger N, Srivatsan SN, Gao F, Romee R, Abboud CN, Uy GL, Westervelt P, Jacoby MA, Pusic I, Stockerl-Goldstein KE, Schroeder MA, DiPersio J, Fehniger TA
    Cancer Discov 2020 Dec;10(12):1854-1871
  • CAR-Modified Memory-Like NK Cells Exhibit Potent Responses to NK-Resistant Lymphomas
    Gang M, Marin ND, Wong P, Neal CC, Marsala L, Foster M, Schappe T, Meng W, Tran J, Schaettler M, Davila M, Gao F, Cashen AF, Bartlett NL, Mehta-Shah N, Kahl BS, Kim MY, Cooper ML, DiPersio JF, Berrien-Elliott MM, Fehniger TA
    Blood 2020 Nov 12;136(20):2308-2318
  • Selective Targeting of Alpha4beta1 Integrin Attenuates Murine Graft Versus Host Disease
    Alahmari B, Cooper ML, Vij K, Ritchey J, Ruminski P, Gao F, Choi J, DiPersio JF
    Leukemia 2020 Nov;34(11):3100-3104
  • Immunotherapy for T-Cell ALL and T-Cell NHL
    DiPersio JF, Staser K, Cooper M
    Clin Lymphoma Myeloma Leuk 2020 Sep;20 Suppl 1:S56-S58
  • Chimeric Antigen Receptor T Cells (CAR-T) for the Treatment of T-Cell Malignancies
    Cooper ML, DiPersio JF
    Best Pract Res Clin Haematol 2019 Dec;32(4):101097
  • Selective Targeting of Histone Modification Fails to Prevent Graft Versus Host Disease After Hematopoietic Cell Transplantation
    Alahmari B, Cooper M, Ziga E, Ritchey J, DiPersio JF, Choi J
    PLoS One 2018 Nov 19;13(11):e0207609
  • Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-Tolerance
    Perry JSA, Russler-Germain EV, Zhou YW, Purtha W, Cooper ML, Choi J, Schroeder MA, Salazar V, Egawa T, Lee BC, Abumrad NA, Kim BS, Anderson MS, DiPersio JF, Hsieh CS
    Immunity 2018 Jun 19;48(6):1271
  • Radionuclides Transform Chemotherapeutics Into Phototherapeutics for Precise Treatment of Disseminated Cancer
    Kotagiri N*, Cooper ML*, Rettig M, Egbulefu C, Prior J, Cui G, Karmakar P, Zhou M, Yang X, Sudlow G, Marsala L, Chanswangphuwana C, Lu L, Habimana-Griffin L, Shokeen M, Xu X, Weilbaecher K, Tomasson M, Lanza G, DiPersio JF, Achilefu S (*Authors contributed equally)
    Nat Commun 2018 Jan 18;9(1):275
  • An "Off-The-Shelf" Fratricide-Resistant CAR-T for the Treatment of T Cell Hematologic Malignancies
    Cooper ML, Choi J, Staser K, Ritchey JK, Devenport JM, Eckardt K, Rettig MP, Wang B, Eissenberg LG, Ghobadi A, Gehrs LN, Prior JL, Achilefu S, Miller CA, Fronick CC, O'Neal J, Gao F, Weinstock DM, Gutierrez A, Fulton RS, DiPersio JF
    Leukemia 2018 Sep;32(9):1970-1983
  • Baricitinib-Induced Blockade of Interferon Gamma Receptor and Interleukin-6 Receptor for the Prevention and Treatment of Graft-Versus-Host Disease
    Choi J, Cooper ML, Staser K, Ashami K, Vij KR, Wang B, Marsala L, Niswonger J, Ritchey J, Alahmari B, Achilefu S, Tsunoda I, Schroeder MA, DiPersio JF
    Leukemia 2018 Nov;32(11):2483-2494
  • Azacitidine Mitigates Graft-Versus-Host Disease Via Differential Effects on the Proliferation of T Effectors and Natural Regulatory T Cells in Vivo
    Cooper ML, Choi J, Karpova D, Vij K, Ritchey J, Schroeder MA, DiPersio JF
    J Immunol 2017 May 1;198(9):3746-3754
  • Gold Nanoclusters Doped With (64)Cu for CXCR4 Positron Emission Tomography Imaging of Breast Cancer and Metastasis
    Zhao Y, Detering L, Sultan D, Cooper ML, You M, Cho S, Meier SL, Luehmann H, Sun G, Rettig M, Dehdashti F, Wooley KL, DiPersio JF, Liu Y
    ACS Nano 2016 Jun 28;10(6):5959-70
  • [(18)F]FHBG PET/CT Imaging of CD34-TK75 Transduced Donor T Cells in Relapsed Allogeneic Stem Cell Transplant Patients: Safety and Feasibility
    Eissenberg LG, Rettig MP, Ritchey JK, Prior JL, Schwarz SW, Frye J, White BS, Fulton RS, Ghobadi A, Cooper ML, Couriel DR, Seegulam ME, Piwnica-Worms D, Dehdashti F, Cornetta K, DiPersio JF
    Mol Ther 2015 Jun;23(6):1110-1122
  • Bortezomib Is a Rapid Mobilizer of Hematopoietic Stem Cells in Mice Via Modulation of the VCAM-1/VLA-4 Axis
    Ghobadi A, Rettig MP, Cooper ML, Holt MS, Ritchey JK, Eissenberg L, DiPersio JF
    Blood 2014 Oct 23;124(17):2752-4
  • Effect of Epigallocatechin-3-Gallate on Graft-Versus-Host Disease
    Choi J, Cooper ML, Ziga ED, Ritchey J, DiPersio JF
    Cell Transplant 2014;23(9):1163-6
  • Pharmacologic Blockade of JAK1/JAK2 Reduces GvHD and Preserves the Graft-Versus-Leukemia Effect
    Choi J, Cooper ML, Alahmari B, Ritchey J, Collins L, Holt M, DiPersio JF
    PLoS One 2014 Oct 7;9(10):e109799
  • F11R Is a Novel Monocyte Prognostic Biomarker for Malignant Glioma
    Pong WW, Walker J, Wylie T, Magrini V, Luo J, Emnett RJ, Choi J, Cooper ML, Griffith M, Griffith OL, Rubin JB, Fuller GN, Piwnica-Worms D, Feng X, Hambardzumyan D, DiPersio JF, Mardis ER, Gutmann DH
    PLoS One 2013 Oct 11;8(10):e77571
  • IFNgammaR Signaling Mediates Alloreactive T-Cell Trafficking and GVHD
    Choi J, Ziga ED, Ritchey J, Collins L, Prior JL, Cooper ML, Piwnica-Worms D, DiPersio JF
    Blood 2012 Nov 8;120(19):4093-103
  • Combined Activity of Oridonin and Wogonin in Advanced-Stage Ovarian Cancer Cells: Sensitivity of Ovarian Cancer Cells to Phyto-Active Chemicals
    Chen S, Cooper M, Jones M, Madhuri TK, Wade J, Bachelor A, Butler-Manuel S
    Cell Biol Toxicol 2011 Apr;27(2):133-47
  • Interaction Between Single Nucleotide Polymorphisms in Selenoprotein P and Mitochondrial Superoxide Dismutase Determines Prostate Cancer Risk
    Cooper ML, Adami HO, Gronberg H, Wiklund F, Green FR, Rayman MP
    Cancer Res 2008 Dec 15;68(24):10171-7
  • Effect of Selenium Status and Supplementation With High-Selenium Yeast on Plasma Homocysteine and B Vitamin Concentrations in the UK Elderly
    Bekaert B, Cooper ML, Green FR, McNulty H, Pentieva K, Scott JM, Molloy AM, Rayman MP
    Mol Nutr Food Res 2008 Nov;52(11):1324-33
  • Selecting for Antibody ScFv Fragments With Improved Stability Using Phage Display With Denaturation Under Reducing Conditions
    Brockmann EC, Cooper M, Stromsten N, Vehniainen M, Saviranta P
    J Immunol Methods 2005 Jan;296(1-2):159-70