Faculty
Oncology Division
Alphabetical list (active faculty):   
Siddhartha Devarakonda

Siddhartha Devarakonda, MBBS, MD

Assistant Professor

Department of Medicine

Oncology Division

Medical Oncology

Clinical Interests

  • Lung cancer
  • Genomics

Contact

  • 314-362-5817 (office)
  • 314-362-3895 (fax)
  • Division of Oncology
    Mail Stop 8056-0029-11
    Washington University
    660 South Euclid Avenue
    St. Louis, MO 63110
  • 11th Floor Mid-Campus Center (office)

Peer-reviewed Manuscripts

  • Overcoming Chemotherapy Resistance in SCLC
    Herzog BH, Devarakonda S, Govindan R
    J Thorac Oncol 2021 Dec;16(12):2002-2015
  • Genomic Profiling of Lung Adenocarcinoma in Never-Smokers
    Devarakonda S, Li Y, Martins Rodrigues F, Sankararaman S, Kadara H, Goparaju C, Lanc I, Pepin K, Waqar SN, Morgensztern D, Ward J, Masood A, Fulton R, Fulton L, Gillette MA, Satpathy S, Carr SA, Wistuba I, Pass H, Wilson RK, Ding L, Govindan R
    J Clin Oncol 2021 Nov 20;39(33):3747-3758
  • A Phase II Study of Everolimus in Patients With Advanced Solid Malignancies With TSC1, TSC2, NF1, NF2 or STK11 Mutations
    Devarakonda S, Pellini B, Verghese L, Park H, Morgensztern D, Govindan R, Suresh R, Oppelt P, Baggstrom MQ, Wu N, Waqar SN
    J Thorac Dis 2021 Jul;13(7):4054-4062
  • Prognostic and Predictive Effect of KRAS Gene Copy Number and Mutation Status in Early Stage Non-Small Cell Lung Cancer Patients
    Fung AS, Karimi M, Michiels S, Seymour L, Brambilla E, Le-Chevalier T, Soria JC, Kratzke R, Graziano SL, Devarakonda S, Govindan R, Tsao MS, Shepherd FA
    Transl Lung Cancer Res 2021 Feb;10(2):826-838
  • Whole-Genome Characterization of Lung Adenocarcinomas Lacking the RTK/RAS/RAF Pathway
    Carrot-Zhang J*, Yao X*, Devarakonda S*, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L, Rheinbay E, Liu EM, Trieu T, Haan D, Yau C, Hinoue T, Liu Y, Shapira O, Kumar K, Mungall KL, Zhang H, Lee JJ, Berger A, Gao GF, Zhitomirsky B, Liang WW, Zhou M, Moorthi S, Berger AH, Collisson EA, Zody MC, Ding L, Cherniack AD, Getz G, Elemento O, Benz CC, Stuart J, Zenklusen JC, Beroukhim R, Chang JC, Campbell JD, Hayes DN, Yang L, Laird PW, Weinstein JN, Kwiatkowski DJ, Tsao MS, Travis WD, Khurana E, Berman BP, Hoadley KA, Robine N, Meyerson M, Govindan R, Imielinski M (*Equal contribution)
    TCGA Research Network

    Cell Rep 2021 Feb 2;34(5):108707
  • Mastering the Complex Targeted Therapy for Non-Small Cell Lung Cancer
    Devarakonda S, Govindan R, Morgensztern D
    Cancer Cell 2020 Sep 14;38(3):320-322
  • MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate
    Ireland AS, Micinski AM, Kastner DW, Guo B, Wait SJ, Spainhower KB, Conley CC, Chen OS, Guthrie MR, Soltero D, Qiao Y, Huang X, Tarapcsak S, Devarakonda S, Chalishazar MD, Gertz J, Moser JC, Marth G, Puri S, Witt BL, Spike BT, Oliver TG
    Cancer Cell 2020 Jul 13;38(1):60-78
  • Biomarker-Driven Staging - Are We There Yet?
    Devarakonda S, Govindan R
    JAMA Netw Open 2019 Dec 2;2(12):e1917052
  • Circulating Tumor DNA Profiling in Small-Cell Lung Cancer Identifies Potentially Targetable Alterations
    Devarakonda S, Sankararaman S, Herzog BH, Gold KA, Waqar SN, Ward JP, Raymond VM, Lanman RB, Chaudhuri AA, Owonikoko TK, Li BT, Poirier JT, Rudin CM, Govindan R, Morgensztern D
    Clin Cancer Res 2019 Oct 15;25(20):6119-6126
  • Untangling the Evolutionary Roots of Lung Cancer
    Devarakonda S, Govindan R
    Nat Commun 2019 Jul 5;10(1):2979
  • Targeting Resistance to Targeted Therapies: Combating a Resilient Foe
    Devarakonda S, Govindan R
    Clin Cancer Res 2018 Dec 15;24(24):6112-6114
  • Early Mortality in Patients Undergoing Adjuvant Chemotherapy for Non-Small Cell Lung Cancer
    Morgensztern D, Samson PS, Waqar SN, Devarakonda S, Robinson CG, Govindan R, Puri V
    J Thorac Oncol 2018 Apr;13(4):543-549
  • Non-Small-Cell Lung Cancer With Brain Metastasis at Presentation
    Waqar SN, Samson PP, Robinson CG, Bradley J, Devarakonda S, Du L, Govindan R, Gao F, Puri V, Morgensztern D
    Clin Lung Cancer 2018 Jul;19(4):e373-e379
  • Tumor Mutation Burden as a Biomarker in Resected Non-Small-Cell Lung Cancer
    Devarakonda S, Rotolo F, Tsao MS, Lanc I, Brambilla E, Masood A, Olaussen KA, Fulton R, Sakashita S, McLeer-Florin A, Ding K, Le Teuff G, Shepherd FA, Pignon JP, Graziano SL, Kratzke R, Soria JC, Seymour L, Govindan R, Michiels S
    J Clin Oncol 2018 Oct 20;36(30):2995-3006
  • Recurrent WNT Pathway Alterations Are Frequent in Relapsed Small Cell Lung Cancer
    Wagner AH*, Devarakonda S*, Skidmore ZL, Krysiak K, Ramu A, Trani L, Kunisaki J, Masood A, Waqar SN, Spies NC, Morgensztern D, Waligorski J, Ponce J, Fulton RS, Maggi LB Jr, Weber JD, Watson MA, O'Conor CJ, Ritter JH, Olsen RR, Cheng H, Mukhopadhyay A, Can I, Cessna MH, Oliver TG, Mardis ER, Wilson RK, Griffith M, Griffith OL, Govindan R (*Equal contribution)
    Nat Commun 2018 Sep 17;9(1):3787
  • TRAC(ERx)-ing Lung Cancer Evolution
    Devarakonda S, Govindan R
    Ann Oncol 2017 Aug 1;28(8):1690-1692
  • Next-Generation Sequencing of Lung Cancers: Lessons Learned and Future Directions
    Devarakonda S, Masood A, Govindan R
    Hematol Oncol Clin North Am 2017 Feb;31(1):1-12
  • Adjuvant Chemotherapy for Patients With T2N0M0 NSCLC
    Morgensztern D, Du L, Waqar SN, Patel A, Samson P, Devarakonda S, Gao F, Robinson CG, Bradley J, Baggstrom M, Masood A, Govindan R, Puri V
    J Thorac Oncol 2016 Oct;11(10):1729-35
  • New Insights Into the Molecular Profile of Lung Adenocarcinoma and Implications for Therapy
    Ganesh B, Devarakonda S, Govindan R
    Expert Rev Anticancer Ther 2015 Apr;15(4):361-4
  • Crizotinib: An Orphan Drug for Treating Non-Small-Cell Lung Cancer
    Devarakonda S, Ganesh B, Mann J, Govindan R
    Expert Opinion on Orphan Drugs 2015;3:1209-18
  • Genomic Alterations in Lung Adenocarcinoma
    Devarakonda S, Morgensztern D, Govindan R
    Lancet Oncol 2015 Jul;16(7):e342-51
  • Clonal Evolution: Multiregion Sequencing of Esophageal Adenocarcinoma Before and After Chemotherapy
    Devarakonda S, Govindan R
    Cancer Discov 2015 Aug;5(8):796-8
  • Clinical Next-Generation Sequencing in Patients With Non-Small Cell Lung Cancer
    Hagemann IS, Devarakonda S, Lockwood CM, Spencer DH, Guebert K, Bredemeyer AJ, Al-Kateb H, Nguyen TT, Duncavage EJ, Cottrell CE, Kulkarni S, Nagarajan R, Seibert K, Baggstrom M, Waqar SN, Pfeifer JD, Morgensztern D, Govindan R
    Cancer 2015 Feb 15;121(4):631-9
  • A Phase I Trial of Sunitinib and Rapamycin in Patients With Advanced Non-Small Cell Lung Cancer
    Waqar SN, Gopalan PK, Williams K, Devarakonda S, Govindan R
    Chemotherapy 2013;59(1):8-13
  • Review of Ongoing Clinical Trials in Non-Small-Cell Lung Cancer: A Status Report for 2012 From the ClinicalTrials.gov Web Site
    Subramanian J, Regenbogen T, Nagaraj G, Lane A, Devarakonda S, Zhou G, Govindan R
    J Thorac Oncol 2013 Jul;8(7):860-5
  • Genomics of Squamous Cell Lung Cancer
    Rooney M, Devarakonda S, Govindan R
    Oncologist 2013 Jun;18(6):707-16
  • Genomic Landscape of Squamous Cell Carcinoma of the Lung
    Morgensztern D, Devarakonda S, Govindan R
    Am Soc Clin Oncol Educ Book 2013:348-53
  • Molecularly Targeted Therapies in Locally Advanced Non-Small-Cell Lung Cancer
    Devarakonda S, Morgensztern D, Govindan R
    Clin Lung Cancer 2013 Sep;14(5):467-72
  • Clinical Applications of the Cancer Genome Atlas Project (TCGA) for Squamous Cell Lung Carcinoma
    Devarakonda S, Morgensztern D, Govindan R
    Oncology (Williston Park) 2013 Sep;27(9):899-906
  • Cancer Gene Sequencing: Ethical Challenges and Promises
    Devarakonda S, Govindan R, Hammerman PS
    Virtual Mentor 2012 Nov 1;14(11):868-72
  • Cardiovascular Risk Among University Students From Developed and Developing Nations
    Bleske BE, Erickson SR, Fahoum S, Devarakonda KR, Welage LS, Koudmani M, Pantham N, Edwin SB, Devarakonda S, Shea MJ, Martha S, Khalidi N
    Open Cardiovasc Med J 2011;5:117-22

Book Chapters

  • Chapter 6: Thoracic Cancers
    Herzog BH, Ellis H, Malik PS, Waqar SN, Devarakonda S, Govindan R, Morgensztern D
    In: DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology Review, 5th Edition (Morgensztern D, Govindan R, Devarakonda S, Trikalinos NA, Editors), Wolters Kluwer, Philadelphia, 2022
  • Chapter 11: Small Cell Lung Cancer
    Ellis H, Badiyan SN, Devarakonda S
    In: The Washington Manual of Oncology, 4th Edition (Morgensztern D, Ghobadi A, Govindan R, Editors), Wolters Kluwer, Philadelphia, 2022
  • Chapter 1: Cancer Biology and Molecular Diagnosis
    Herzog BH, Devarakonda S
    In: The Washington Manual of Oncology, 4th Edition (Morgensztern D, Ghobadi A, Govindan R, Editors), Wolters Kluwer, Philadelphia, 2022
  • Chapter 22: Cancer
    Devarakonda S, Cashen A, Morgensztern D, Govindan R
    In: The Washington Manual of Medical Therapeutics, 36th Edition (Crees Z, Fritz C, Heudebert A, Noe J, Rengarajan A, Wang X, editors), Wolters-Kluwer, Philadelphia, 2020
  • Chapter 1: Role of Next-Generation Sequencing Technologies
    Devarakonda S, Morgensztern D, Govindan R
    In: Targeted Therapies in Oncology, Second Edition. Taylor & Francis
  • Chemotherapy in Early Stage Lung Cancer
    Subramanian J, Devarakonda S, Rajagopal K, Waqar S, Govindan R
    In: Thoracic Oncology: A Multidisciplinary Approach
  • Genomics: From Research Tool to the Lung Cancer Clinic
    Devarakonda S, Morgensztern D, Belani CP, Govindan R
    In: 2013 WCLC Educational Book
  • Cancer Biology
    Devarakonda S
    In: Washington University Consult Manual for Hematology and Oncology
  • Cancer Genomics
    Devarakonda S
    In: Washington University Consult Manual for Hematology and Oncology
  • Carcinoma of Unknown Primary
    Devarakonda S, Carpenter D, Morgensztern D
    In: The Washington Manual Hematology and Oncology Subspecialty Consult, 4th edition
  • Thymoma and Mesothelioma
    Knoche E, Devarakonda S, Morgensztern D
    In: The Washington Manual Hematology and Oncology Subspecialty Consult, 4th edition
  • Cancer
    Devarakonda S, Morgensztern D, Govindan R
    In: Washington Manual of Medical therapeutics, 35th edition
  • Neoadjuvant Chemotherapy
    Devarakonda S, Morgensztern D, Waqar SN
    In: Shields Textbook of Thoracic Surgery
  • Lung Cancer and Mesothelioma
    Devarakonda S, Waqar SN
    In: DeVita, Hellman and Rosenberg’s Cancer: Principles and Practice of Oncology Review. Fourth Edition