Faculty
Oncology Division
Alphabetical list (active faculty):   
Francesca Ferraro

Francesca Ferraro, MD, PhD

Assistant Professor

Department of Medicine

Oncology Division

Bone Marrow Transplantation & Leukemia

Clinical Interests

  • Acute myeloid leukemia

Contact

  • 314-273-6878 (office)
  • 314-273-1308 (lab)
  • 314-362-9333 (fax)
  • Division of Oncology
    Mail Stop 8007-0029-11
    Washington University
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Room 613, Southwest Tower (lab)

Peer-reviewed Manuscripts

  • Functional and Epigenetic Phenotypes of Humans and Mice With DNMT3A Overgrowth Syndrome
    Smith AM, LaValle TA, Shinawi M, Ramakrishnan SM, Abel HJ, Hill CA, Kirkland NM, Rettig MP, Helton NM, Heath SE, Ferraro F, Chen DY, Adak S, Semenkovich CF, Christian DL, Martin JR, Gabel HW, Miller CA, Ley TJ
    Nat Commun 2021 Jul 27;12(1):4549
  • Comparing Transplant Outcomes in ALL Patients After Haploidentical With PTCy or Matched Unrelated Donor Transplantation
    Al Malki MM, Yang D, Labopin M, Afanasyev B, Angelucci E, Bashey A, Socie G, Karduss-Urueta A, Helbig G, Bornhauser M, Niittyvuopio R, Ganser A, Ciceri F, Brecht A, Koc Y, Bejanyan N, Ferraro F, Kebriaei P, Mokhtari S, Ghobadi A, Nakamura R, Forman SJ, Champlin R, Mohty M, Ciurea SO, Nagler A
    Blood Adv 2020 May 12;4(9):2073-2083
  • Secondary Acute Lymphoblastic Leukemia, a Retrospective Analysis From Washington University and Meta-Analysis of Published Data
    Ferraro F, Gao F, Stockerl-Goldstein K, Westervelt P, DiPersio JF, Ghobadi A
    Leuk Res 2018 Sep;72:86-91
  • Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia
    Di Marcantonio D, Martinez E, Sidoli S, Vadaketh J, Nieborowska-Skorska M, Gupta A, Meadows JM, Ferraro F, Masselli E, Challen GA, Milsom MD, Scholl C, Frohling S, Balachandran S, Skorski T, Garcia BA, Mirandola P, Gobbi G, Garzon R, Vitale M, Sykes SM
    Clin Cancer Res 2018 Feb 1;24(3):608-618
  • JUN Is a Key Transcriptional Regulator of the Unfolded Protein Response in Acute Myeloid Leukemia
    Zhou C, Martinez E, Di Marcantonio D, Solanki-Patel N, Aghayev T, Peri S, Ferraro F, Skorski T, Scholl C, Frohling S, Balachandran S, Wiest DL, Sykes SM
    Leukemia 2017 May;31(5):1196-1205
  • Distinctive Mesenchymal-Parenchymal Cell Pairings Govern B Cell Differentiation in the Bone Marrow
    Yu VW, Lymperi S, Oki T, Jones A, Swiatek P, Vasic R, Ferraro F, Scadden DT
    Stem Cell Reports 2016 Aug 9;7(2):220-35
  • Bone Marrow Macrophages Contribute to Diabetic Stem Cell Mobilopathy by Producing Oncostatin M
    Albiero M, Poncina N, Ciciliot S, Cappellari R, Menegazzo L, Ferraro F, Bolego C, Cignarella A, Avogaro A, Fadini GP
    Diabetes 2015 Aug;64(8):2957-68
  • Transcriptome Comparison of Distinct Osteolineage Subsets in the Hematopoietic Stem Cell Niche Using a Triple Fluorescent Transgenic Mouse Model
    Yu VW, Lymperi S, Ferraro F, Scadden DT
    Genom Data 2015 Jun 5;5:318-9
  • Specific Bone Cells Produce DLL4 to Generate Thymus-Seeding Progenitors From Bone Marrow
    Yu VW, Saez B, Cook C, Lotinun S, Pardo-Saganta A, Wang YH, Lymperi S, Ferraro F, Raaijmakers MH, Wu JY, Zhou L, Rajagopal J, Kronenberg HM, Baron R, Scadden DT
    J Exp Med 2015 May 4;212(5):759-74
  • The Microanatomy of the Leukemic Stem Cell Niche in Murine Chronic Myelogenous Leukemia
    Meister M, Spencer J, Wu J, Zhao C, Lymperi S, Ferraro F, LoCelso C, Scadden D, Van Etten R, Lin C, Krause D
    Blood 2014 Dec 6;124(21):351
  • Inhibiting Stromal Cell Heparan Sulfate Synthesis Improves Stem Cell Mobilization and Enables Engraftment Without Cytotoxic Conditioning
    Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Toro RD, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT
    Blood 2014 Nov 6;124(19):2937-47
  • Direct Measurement of Local Oxygen Concentration in the Bone Marrow of Live Animals
    Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, Yusuf R, Cote D, Vinogradov SA, Scadden DT, Lin CP
    Nature 2014 Apr 10;508(7495):269-73
  • Proplatelet Generation in the Mouse Requires PKCepsilon-Dependent RhoA Inhibition
    Gobbi G, Mirandola P, Carubbi C, Masselli E, Sykes SM, Ferraro F, Nouvenne A, Thon JN, Italiano JE Jr, Vitale M
    Blood 2013 Aug 15;122(7):1305-11
  • Differential Stem- and Progenitor-Cell Trafficking by Prostaglandin E2
    Hoggatt J, Mohammad KS, Singh P, Hoggatt AF, Chitteti BR, Speth JM, Hu P, Poteat BA, Stilger KN, Ferraro F, Silberstein L, Wong FK, Farag SS, Czader M, Milne GL, Breyer RM, Serezani CH, Scadden DT, Guise TA, Srour EF, Pelus LM
    Nature 2013 Mar 21;495(7441):365-9
  • Diabetes Impairs Hematopoietic Stem Cell Mobilization by Altering Niche Function
    Ferraro F, Lymperi S, Mendez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT
    Sci Transl Med 2011 Oct 12;3(104):104ra101
  • Differential Niche and Wnt Requirements During Acute Myeloid Leukemia Progression
    Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA
    Blood 2011 Sep 8;118(10):2849-56
  • AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias
    Sykes SM, Lane SW, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, Ferraro F, Mercier F, Singh H, Brumme KM, Acharya SS, Scholl C, Tothova Z, Attar EC, Frohling S, DePinho RA, Armstrong SA, Gilliland DG, Scadden DT
    Cell 2011 Sep 2;146(5):697-708
  • Guanine Nucleotide Exchange Factor Vav1 Regulates Perivascular Homing and Bone Marrow Retention of Hematopoietic Stem and Progenitor Cells
    Sanchez-Aguilera A, Lee YJ, Lo Celso C, Ferraro F, Brumme K, Mondal S, Kim C, Dorrance A, Luo HR, Scadden DT, Williams DA
    Proc Natl Acad Sci U S A 2011 Jun 7;108(23):9607-12
  • Inhibition of Osteoclast Function Reduces Hematopoietic Stem Cell Numbers in Vivo
    Lymperi S, Ersek A, Ferraro F, Dazzi F, Horwood NJ
    Blood 2011 Feb 3;117(5):1540-9
  • Mesenchymal and Haematopoietic Stem Cells Form a Unique Bone Marrow Niche
    Mendez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS
    Nature 2010 Aug 12;466(7308):829-34

Reviews and Book Chapters

  • Hematologic Disorders and Transfusion Therapy
    Zhou A, Ferraro F, Jackups R, Blinder M
    In: The Washington Manual of Medical Therapeutics, 36th Edition (Crees Z, Fritz C, Heudebert A, Noe J, Rengarajan A, Wang X, editors), Wolters-Kluwer, Philadelphia, 2020
  • Concise Review: Diabetes, the Bone Marrow Niche, and Impaired Vascular Regeneration
    Fadini GP, Ferraro F, Quaini F, Asahara T, Madeddu P
    Stem Cells Transl Med 2014 Aug;3(8):949-57
  • The Skeletal Stem Cell
    Park D, Hoggatt J, Ferraro F, Scadden D
    In: Osteoporosis, Vol. 2 (4th edition, Marcus R, editor), Elsevier, Waltham, MA, 2013; pp 127-147
  • The HSC Niche Concept Has Turned 31. Has Our Knowledge Matured?
    Lymperi S, Ferraro F, Scadden DT
    Ann N Y Acad Sci 2010 Mar;1192:12-8
  • Adult Stem Cels and Their Niches
    Ferraro F, Celso CL, Scadden D
    Adv Exp Med Biol 2010;695:155-68