Faculty
Ghobadi.jpg

Armin Ghobadi, MD

Assistant Professor
Department of Medicine
Oncology Division
Bone Marrow Transplantation & Leukemia

Research Interests

  • Hematopoietic stem cell transplantation
  • Immunotherapy
  • Genome sequencing

Contact

  • 314-454-2743 (tel)
  • 314-454-7551 (fax)
  • 11th Floor Mid-Campus Center (office)
  • Division of Oncology
    Campus Box 8007
    Washington University Medical School
    660 South Euclid Avenue
    St. Louis, MO 63110

Peer-reviewed Manuscripts

  • Next Generation Sequencing-Based Validation of the Revised International Staging System for Multiple Myeloma: An Analysis of the MMRF CoMMpass Study
    Goldsmith SR, Fiala MA, Dukeman J, Ghobadi A, Stockerl-Goldstein K, Schroeder MA, Tomasson M, Wildes TM, Vij R
    Clin Lymphoma Myeloma Leuk 2019 Jan 19; [Epub ahead of print]
  • HLA-DP Mismatch and CMV Reactivation Increase Risk of AGVHD Independently in Recipients of Allogeneic Stem Cell Transplant
    Ghobadi A, Milton DR, Gowda L, Rondon G, Chemaly RF, Hamdi A, Alousi A, Afrough A, Oran B, Ciurea S, Kebriaei P, Popat UR, Qazilbash MH, Shpall EJ, Champlin RE, Bashir Q
    Curr Res Transl Med 2019 Jan 22; [Epub ahead of print]
  • ASBMT Consensus Grading for Cytokine Release Syndrome and Neurological Toxicity Associated With Immune Effector Cells
    Lee DW, Santomasso BD, Locke FL, Ghobadi A, Turtle CJ, Brudno JN, Maus MV, Park JH, Mead E, Pavletic S, Go WY, Eldjerou L, Gardner RA, Frey N, Curran KJ, Peggs K, Pasquini M, DiPersio JF, van den Brink MRM, Komanduri KV, Grupp SA, Neelapu SS
    Biol Blood Marrow Transplant 2018 Dec 25; [Epub ahead of print]
  • Clinical Utilization of Chimeric Antigen Receptors T-Cells (CAR-T) in B-Cell Acute Lymphoblastic Leukemia (ALL) - An Expert Opinion From the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Transplantation (ASBMT)
    Kansagra AJ, Frey NV, Bar M, Laetsch TW, Carpenter PA, Savani BN, Heslop HE, Bollard CM, Komanduri KV, Gastineau DA, Chabannon C, Perales MA, Hudecek M, Aljurf M, Andritsos L, Barrett JA, Bachanova V, Bonini C, Ghobadi A, Gill SI, Hill J, Kenderian S, Kebriaei P, Nagler A, Maloney D, Liu HD, Shah NN, Kharfan-Dabaja MA, Shpall EJ, Mufti GJ, Johnston L, Jacoby E, Bazarbachi A, DiPersio JF, Pavletic SZ, Porter DL, Grupp SA, Sadelain M, Litzow MR, Mohty M, Hashmi SK
    Biol Blood Marrow Transplant 2018 Dec 18; [Epub ahead of print]
  • Long-Term Safety and Activity of Axicabtagene Ciloleucel in Refractory Large B-Cell Lymphoma (ZUMA-1): A Single-Arm, Multicentre, Phase 1-2 Trial
    Locke FL, Ghobadi A, Jacobson CA, Miklos DB, Lekakis LJ, Oluwole OO, Lin Y, Braunschweig I, Hill BT, Timmerman JM, Deol A, Reagan PM, Stiff P, Flinn IW, Farooq U, Goy A, McSweeney PA, Munoz J, Siddiqi T, Chavez JC, Herrera AF, Bartlett NL, Wiezorek JS, Navale L, Xue A, Jiang Y, Bot A, Rossi JM, Kim JJ, Go WY, Neelapu SS
    Lancet Oncol 2019 Jan;20(1):31-42
  • An "Off-The-Shelf" Fratricide-Resistant CAR-T for the Treatment of T Cell Hematologic Malignancies
    Cooper ML, Choi J, Staser K, Ritchey JK, Devenport JM, Eckardt K, Rettig MP, Wang B, Eissenberg LG, Ghobadi A, Gehrs LN, Prior JL, Achilefu S, Miller CA, Fronick CC, O'Neal J, Gao F, Weinstock DM, Gutierrez A, Fulton RS, DiPersio JF
    Leukemia 2018 Sep;32(9):1970-1983
  • Multiple Myeloma Patients Ineligible for Randomized Controlled Trials Have Poorer Outcomes Irrespective of Treatment
    Malecek MK, Fiala M, Schroeder M, Dukeman J, Ghobadi A, Stockerl-Goldstein K, Wildes T, Vij R
    Clin Lymphoma Myeloma Leuk 2018 Sep;18(9):e363-e364
  • Secondary Acute Lymphoblastic Leukemia, a Retrospective Analysis From Washington University and Meta-Analysis of Published Data
    Ferraro F, Gao F, Stockerl-Goldstein K, Westervelt P, DiPersio JF, Ghobadi A
    Leuk Res 2018 Jul 31;72:86-91; [Epub ahead of print]
  • Ixazomib, an Oral Proteasome Inhibitor, Induces Rapid Mobilization of Hematopoietic Progenitor Cells in Mice
    Ghobadi A, Rettig MP, Holt MS, Ritchey JK, Kennerly K, Chendamarai E, Eissenberg L, DiPersio JF
    Blood 2018 Jun 7;131(23):2594-2596
  • Chimeric Antigen Receptor T Cell Therapy for Non-Hodgkin Lymphoma
    Ghobadi A
    Curr Res Transl Med 2018 May;66(2):43-49
  • Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
    Neelapu SS, Locke FL, Bartlett NL, Lekakis LJ, Miklos DB, Jacobson CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, Timmerman JM, Stiff PJ, Friedberg JW, Flinn IW, Goy A, Hill BT, Smith MR, Deol A, Farooq U, McSweeney P, Munoz J, Avivi I, Castro JE, Westin JR, Chavez JC, Ghobadi A, Komanduri KV, Levy R, Jacobsen ED, Witzig TE, Reagan P, Bot A, Rossi J, Navale L, Jiang Y, Aycock J, Elias M, Chang D, Wiezorek J, Go WY
    N Engl J Med 2017 Dec 28;377(26):2531-2544
  • Patterns of Infectious Complications in Acute Myeloid Leukemia and Myelodysplastic Syndromes Patients Treated With 10-Day Decitabine Regimen
    Ali AM, Weisel D, Gao F, Uy GL, Cashen AF, Jacoby MA, Wartman LD, Ghobadi A, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Schroeder MA, Westervelt P, DiPersio JF, Welch JS
    Cancer Med 2017 Dec;6(12):2814-2821
  • Fresh or Cryopreserved CD34+-Selected Mobilized Peripheral Blood Stem and Progenitor Cells for the Treatment of Poor Graft Function After Allogeneic Hematopoietic Cell Transplantation
    Ghobadi A, Fiala MA, Ramsingh G, Gao F, Abboud CN, Stockerl-Goldstein K, Uy GL, Grossman BJ, Westervelt P, DiPersio JF
    Biol Blood Marrow Transplant 2017 Jul;23(7):1072-1077
  • Donor-Derived Smoldering Multiple Myeloma Following a Hematopoietic Cell Transplantation for AML
    Fakhri B, Fiala M, Slade M, Westervelt P, Ghobadi A
    Case Rep Hematol 2017;2017:3728429
  • Phase 1 Results of ZUMA-1: A Multicenter Study of KTE-C19 Anti-CD19 CAR T Cell Therapy in Refractory Aggressive Lymphoma
    Locke FL, Neelapu SS, Bartlett NL, Siddiqi T, Chavez JC, Hosing CM, Ghobadi A, Budde LE, Bot A, Rossi JM, Jiang Y, Xue AX, Elias M, Aycock J, Wiezorek J, Go WY
    Mol Ther 2017 Jan 4;25(1):285-295
  • TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes
    Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Cashen AF, Schroeder MA, Jacoby MA, Heath SE, Luber K, Janke MR, Hantel A, Khan N, Sukhanova MJ, Knoebel RW, Stock W, Graubert TA, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ
    N Engl J Med 2016 Nov 24;375(21):2023-2036
  • Phase II Study of Propylene Glycol-Free Melphalan Combined With Carmustine, Etoposide, and Cytarabine for Myeloablative Conditioning in Lymphoma Patients Undergoing Autologous Stem Cell Transplantation
    Cashen AF, Fletcher T, Ceriotti C, Gao F, Ghobadi A, Vij R, Stockerl-Goldstein K, DiPersio J, Abboud C
    Biol Blood Marrow Transplant 2016 Dec;22(12):2155-2158
  • Phase I Study of Azacitidine Following Donor Lymphocyte Infusion for Relapsed Acute Myeloid Leukemia Post Allogeneic Stem Cell Transplantation
    Ghobadi A, Choi J, Fiala MA, Fletcher T, Liu J, Eissenberg LG, Abboud C, Cashen A, Vij R, Schroeder MA, Pusic I, Stockerl-Goldstein K, Jacoby M, Uy G, DiPersio J, Westervelt P
    Leuk Res 2016 Oct;49:1-6
  • Chemotherapy Versus Hypomethylating Agents for the Treatment of Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndrome After Allogeneic Stem Cell Transplant
    Motabi IH, Ghobadi A, Liu J, Schroeder M, Abboud CN, Cashen AF, Stockerl-Goldstein KE, Uy GL, Vij R, Westervelt P, DiPersio JF
    Biol Blood Marrow Transplant 2016 Jul;22(7):1324-9
  • High-Throughput Sequencing of Cerebrospinal Fluid for Diagnosis of Chronic Propionibacterium Acnes Meningitis in an Allogeneic Stem Cell Transplant Recipient
    Wylie KM, Blanco-Guzman M, Wylie TN, Lawrence SJ, Ghobadi A, DiPersio JF, Storch GA
    Transpl Infect Dis 2016 Apr;18(2):227-33
  • [(18)F]FHBG PET/CT Imaging of CD34-TK75 Transduced Donor T Cells in Relapsed Allogeneic Stem Cell Transplant Patients: Safety and Feasibility
    Eissenberg LG, Rettig MP, Ritchey JK, Prior JL, Schwarz SW, Frye J, White BS, Fulton RS, Ghobadi A, Cooper ML, Couriel DR, Seegulam ME, Piwnica-Worms D, Dehdashti F, Cornetta K, DiPersio JF
    Mol Ther 2015 Jun;23(6):1110-22
  • Retrospective Comparison of Allogeneic Vs Autologous Transplantation for Diffuse Large B-Cell Lymphoma With Early Relapse or Primary Induction Failure
    Ghobadi A, Nolley E, Liu J, McBride A, Stockerl-Goldstein K, Cashen A
    Bone Marrow Transplant 2015 Jan;50(1):134-136
  • Bortezomib Is a Rapid Mobilizer of Hematopoietic Stem Cells in Mice Via Modulation of the VCAM-1/VLA-4 Axis
    Ghobadi A, Rettig MP, Cooper ML, Holt MS, Ritchey JK, Eissenberg L, DiPersio JF
    Blood 2014 Oct 23;124(17):2752-4
  • Conservative Management of Pneumatosis Intestinalis After Allogeneic Hematopoietic SCT
    Bhamidipati PK, Ghobadi A, Bauer S, DiPersio JF, Pusic I
    Bone Marrow Transplant 2014 Nov;49(11):1436-8
  • Effect of Postremission Therapy Before Reduced-Intensity Conditioning Allogeneic Transplantation for Acute Myeloid Leukemia in First Complete Remission
    Warlick ED, Paulson K, Brazauskas R, Zhong X, Miller AM, Camitta BM, George B, Savani BN, Ustun C, Marks DI, Waller EK, Baron F, Freytes CO, Socie G, Akpek G, Schouten HC, Lazarus HM, Horwitz EM, Koreth J, Cahn JY, Bornhauser M, Seftel M, Cairo MS, Laughlin MJ, Sabloff M, Ringden O, Gale RP, Kamble RT, Vij R, Gergis U, Mathews V, Saber W, Chen YB, Liesveld JL, Cutler CS, Ghobadi A, Uy GL, Eapen M, Weisdorf DJ, Litzow MR
    Biol Blood Marrow Transplant 2014 Feb;20(2):202-8
  • A Phase I Study of Azacitidine After Donor Lymphocyte Infusion for Relapsed Acute Myeloid Leukemia Post Allogeneic Stem Cell Transplantation
    Ghobadi A, Fiala M, Abboud CN, Cashen A, Eissenberg L, Graubert T, Jacoby M, Pusic I, Schroeder MA, Stockerl-Goldstein KE, Tomasson MH, Uy GE, Vij R, Walter MJ, DiPersio JF, Westervelt P
    Blood (ASH Annual Meeting Abstracts) 2013 Dec;122(21):3320
  • The Effect of CMV Reactivation on Relapse and Survival in Patients With AML and MDS After Allogeneic Stem Cell Transplant (Allo-HCT)
    Ghobadi A, Hamdi A, Kongtim P, Milton D, Alousi A, Anderlini P, Ciurea SO, Oran B, Khouri I, Parmar S, Qazilbash MH, Kebriaei P, Popat UR, Rezvani K, Chemaly RF, Shpall EJ, Champlin RE, Bashir Q
    Blood (ASH Annual Meeting Abstracts) 2013;122(21):4531
  • ALT-1188: A New CXCR4 Antagonist in Development for Mobilization of HSPCs
    Rettig M, Ghobadi A, Holt M, Meier S, Ritchey J, Tahirovic Y, Bridges A, Gooding D, DiPersio JF
    Blood (ASH Annual Meeting Abstracts) 2013;122(21):891
  • Salvage Second Hematopoietic Cell Transplantation in Myeloma
    Michaelis LC, Saad A, Zhong X, Le-Rademacher J, Freytes CO, Marks DI, Lazarus HM, Bird JM, Holmberg L, Kamble RT, Kumar S, Lill M, Meehan KR, Saber W, Schriber J, Tay J, Vogl DT, Wirk B, Savani BN, Gale RP, Vesole DH, Schiller GJ, Abidi M, Anderson KC, Nishihori T, Kalaycio ME, Vose JM, Moreb JS, Drobyski W, Munker R, Roy V, Ghobadi A, Holland HK, Nath R, To LB, Maiolino A, Kassim AA, Giralt SA, Landau H, Schouten HC, Maziarz RT, Michael J, Kindwall-Keller T, Stiff PJ, Gibson J, Lonial S, Krishnan A, Dispenzieri A, Hari P
    Biol Blood Marrow Transplant 2013 May;19(5):760-6
  • The Effect of Bortezomib (B) Alone or in Combination With Other Agents for Stem Cell Mobilization in Mice
    Ghobadi A, Holt M, Ritchey J, DiPersio JF
    Blood (ASH Annual Meeting Abstracts) 2012;120:583
  • Oral Valganciclovir Versus Ganciclovir as Delayed Pre-Emptive Therapy for Patients After Allogeneic Hematopoietic Stem Cell Transplant: A Pilot Trial (04-0274) and Review of the Literature
    Chawla JS, Ghobadi A, Mosley J 3rd, Verkruyse L, Trinkaus K, Abboud CN, Cashen AF, Stockerl-Goldstein KE, Uy GL, Westervelt P, DiPersio JF, Vij R
    Transpl Infect Dis 2012 Jun;14(3):259-67
  • The Incidence and Impact of Comorbidity on Survival and Selection of Initial Treatment in Elderly Patients With Head and Neck Cancer
    Ghobadi A, Athar M, Dowell J
    J Clin Oncol 2009;27:15s
  • Rectal GI Stromal Tumor Mimicking a Prostate Mass
    Ghobadi A, Kabbani W, Barker B, Dowell JE
    J Clin Oncol 2007 Dec 20;25(36):5827-8