Faculty
Oncology Division
Alphabetical list (active faculty):   
Karolyn A. Oetjen

Karolyn A. Oetjen, MD, PhD

Instructor

Department of Medicine

Oncology Division

Stem Cell Biology

Clinical Interests

  • Myelodysplastic syndromes
  • Acute myeloid leukemia

Research Interests

  • Malignant clonal evolution

Contact

  • 314-362-8872 (office)
  • 314-362-1953 (fax)
  • Division of Oncology
    Mail Stop 8007-0057-07
    Washington University
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Room 724 Southwest Tower (lab)

Research

My clinical interest is myelodysplastic syndromes and acute myeloid leukemia, with particular interest in therapy-related myeloid neoplasms and inherited predisposition to myeloid malignancies. The poor prognosis of relapsed, refractory and therapy-related myeloid neoplasms is an unmet clinical need for the development of novel therapeutics and cellular therapies. A primary focus of my research is applying single-cell genomic techniques to understand malignant clonal evolution within the bone marrow following chemotherapy treatment or hematopoietic stem cell transplantation, specifically in the setting of pre-existing mutations in DNA-damage repair genes.