Oncology Division
Alphabetical list (active faculty):   
Peter J. Oppelt

Peter J. Oppelt, MD

Assistant Professor

Department of Medicine

Oncology Division

Medical Oncology

Clinical Interests

  • Sarcoma
  • Head/neck cancer

Research Interests

  • Sarcoma


  • 636-916-9920 (office)
  • 636-916-9087 (fax)
  • Division of Oncology
    Mail Stop 8056-0513-01
    Washington University
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Siteman Cancer Center St. Peters
    150 Entrance Way
    St. Peters, MO 63376 (office)

Original Articles

  • Phase II Study of Dacarbazine Given With Modern Prophylactic Anti-Emetics and Growth Factor Support to Patients With Metastatic, Resistant Soft Tissue, and Bone Sarcoma
    Van Tine BA, Weiss MC, Hirbe AC, Oppelt PJ, Abaricia S, Trinkaus K, Luo J, Berry S, Ruff T, Callahan C, Toensikoetter J, Ley J, Siegel MJ, Dehdashti F, Siegel BA, Adkins DR
    Rare Tumors 2021 Oct 8;13:20363613211052498
  • A Phase II Study of Everolimus in Patients With Advanced Solid Malignancies With TSC1, TSC2, NF1, NF2 or STK11 Mutations
    Devarakonda S, Pellini B, Verghese L, Park H, Morgensztern D, Govindan R, Suresh R, Oppelt P, Baggstrom MQ, Wu N, Waqar SN
    J Thorac Dis 2021 Jul;13(7):4054-4062
  • Phase II Study of Pazopanib With Oral Topotecan in Patients With Metastatic and Non-Resectable Soft Tissue and Bone Sarcomas
    Schulte B, Mohindra N, Milhem M, Attia S, Robinson S, Monga V, Hirbe AC, Oppelt P, Charlson J, Helenowski I, Abbinanti S, Cehic R, Okuno S, Van Tine BA, Agulnik M
    Br J Cancer 2021 Aug;125(4):528-533
  • Interim Analysis of the Phase II Study: Noninferiority Study of Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for Advanced or Metastatic Soft-Tissue Sarcoma
    Van Tine BA, Hirbe AC, Oppelt P, Frith AE, Rathore R, Mitchell JD, Wan F, Berry S, Landeau M, Heberton GA, Gorcsan J 3rd, Huntjens PR, Soyama Y, Vader JM, Alvarez-Cardona JA, Zhang KW, Lenihan DJ, Krone RJ
    Clin Cancer Res 2021 Jul 15;27(14):3854-3860
  • Pembrolizumab Plus Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: An Open-Label, Multi-Arm, Non-Randomised, Multicentre, Phase 2 Trial
    Sacco AG, Chen R, Worden FP, Wong DJL, Adkins D, Swiecicki P, Chai-Ho W, Oppelt P, Ghosh D, Bykowski J, Molinolo A, Pittman E, Estrada MV, Gold K, Daniels G, Lippman SM, Natsuhara A, Messer K, Cohen EEW
    Lancet Oncol 2021 Jun;22(6):883-892
  • Concurrent Paclitaxel and Radiation Therapy for the Treatment of Cutaneous Angiosarcoma
    Roy A, Gabani P, Davis EJ, Oppelt P, Merfeld E, Keedy VL, Zoberi I, Chrisinger JSA, Michalski JM, Van Tine B, Spraker MB
    Clin Transl Radiat Oncol 2021 Jan 28;27:114-120
  • Palbociclib and Cetuximab Compared With Placebo and Cetuximab in Platinum-Resistant, Cetuximab-Naive, Human Papillomavirus-Unrelated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Double-Blind, Randomized, Phase 2 Trial
    Adkins DR, Lin JC, Sacco A, Ley J, Oppelt P, Vanchenko V, Komashko N, Yen CJ, Wise-Draper T, Lopez-Picazo Gonzalez J, Radulovic S, Shen Q, Thurm H, Martini JF, Hoffman J, Huang X, Melichar B, Tahara M
    Oral Oncol 2021 Apr;115:105192
  • Nanoparticle Albumin-Bound Paclitaxel With Cetuximab and Carboplatin as First-Line Therapy for Recurrent or Metastatic Head and Neck Cancer: A Single-Arm, Multicenter, Phase 2 Trial
    Adkins D, Ley J, Atiq O, Powell S, Spanos WC, Gitau M, Rigden C, Palka K, Liu J, Oppelt P
    Oral Oncol 2021 Apr;115:105173
  • Nab-Paclitaxel and Cisplatin Followed by Cisplatin and Radiation (Arm 1) and Nab-Paclitaxel Followed by Cetuximab and Radiation (Arm 2) for Locally Advanced Head and Neck Squamous-Cell Carcinoma: A Multicenter, Non-Randomized Phase 2 Trial
    Oppelt P, Ley J, Daly M, Rich J, Paniello R, Jackson RS, Pipkorn P, Liu J, Gay H, Palka K, Neupane P, Powell S, Spanos WC, Gitau M, Zevallos J, Thorstad W, Adkins D
    Med Oncol 2021 Mar 8;38(4):35
  • Palbociclib and Cetuximab in Cetuximab-Resistant Human Papillomavirus-Related Oropharynx Squamous-Cell Carcinoma: A Multicenter Phase 2 Trial
    Oppelt P, Ley JC, Worden F, Palka K, Maggiore R, Liu J, Adkins D
    Oral Oncol 2021 Mar;114:105164
  • Outcomes of Patients With Single-Node Metastasis of Human Papillomavirus-Related Oropharyngeal Cancer Treated With Transoral Surgery
    Chen SY, Sinha P, Last A, Ettyreddy A, Kallogjeri D, Pipkorn P, Rich JT, Zevallos JP, Paniello R, Puram SV, Van Abel K, Moore EJ, Oppelt P, Palka K, Adkins D, Daly M, Gay H, Thorstad WL, Jackson RS
    JAMA Otolaryngol Head Neck Surg 2021 Jan 1;147(1):16-22
  • False-Positive Pregnancy Test Secondary to Ectopic Expression of Human Chorionic Gonadotropin by a Gastrointestinal Stromal Tumor
    Andruska N, Mahapatra L, Brenneman R, MacArthur KM, Oppelt P, Baumann BC
    J Surg Oncol 2020 Jul 2; [Epub ahead of print]
  • A Retrospective Analysis of the Efficacy of Immunotherapy in Metastatic Soft-Tissue Sarcomas
    Monga V, Skubitz KM, Maliske S, Mott SL, Dietz H, Hirbe AC, Van Tine BA, Oppelt P, Okuno S, Robinson S, O'Connor M, Seetharam M, Attia S, Charlson J, Agulnik M, Milhem M
    Cancers (Basel) 2020 Jul 11;12(7)
  • Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial
    Uppaluri R, Campbell KM, Egloff AM, Zolkind P, Skidmore ZL, Nussenbaum B, Paniello RC, Rich JT, Jackson R, Pipkorn P, Michel LS, Ley J, Oppelt P, Dunn GP, Barnell EK, Spies NC, Lin T, Li T, Mulder DT, Hanna Y, Cirlan I, Pugh TJ, Mudianto T, Riley R, Zhou L, Jo VY, Stachler MD, Hanna GJ, Kass J, Haddad R, Schoenfeld JD, Gjini E, Lako A, Thorstad W, Gay HA, Daly M, Rodig SJ, Hagemann IS, Kallogjeri D, Piccirillo JF, Chernock RD, Griffith M, Griffith OL, Adkins DR
    Clin Cancer Res 2020 Oct 1;26(19):5140-5152
  • Extranodal Extension Is a Strong Prognosticator in HPV-Positive Oropharyngeal Squamous Cell Carcinoma
    Bauer E, Mazul A, Chernock R, Rich J, Jackson RS, Paniello R, Pipkorn P, Oppelt P, Gay H, Daly M, El-Mofty S, Thorstad W, Adkins D, Zevallos J
    Laryngoscope 2020 Apr;130(4):939-945
  • Abscopal Effect Following Proton Beam Radiotherapy in a Patient With Inoperable Metastatic Retroperitoneal Sarcoma
    Brenneman RJ, Sharifai N, Fischer-Valuck B, Hassanzadeh C, Guzelian J, Chrisinger JSA, Michalski JM, Oppelt PJ, Baumann BC
    Front Oncol 2019 Sep 26;9:922
  • Association of Posttreatment Lymphopenia and Elevated Neutrophil-To-Lymphocyte Ratio With Poor Clinical Outcomes in Patients With Human Papillomavirus-Negative Oropharyngeal Cancers
    Lin AJ, Gang M, Rao YJ, Campian JL, Daly M, Gay H, Oppelt PJ, Jackson RS, Rich J, Paniello R, Zevallos J, Hallahan D, Adkins DR, Thorstad W
    JAMA Otolaryngol Head Neck Surg 2019 May 1;145(5):413-421
  • Patterns of Care and Survival Outcomes for Laryngeal Small Cell Cancer
    Lin AJ, Gabani P, Fischer-Valuck B, Rudra S, Gay H, Daly M, Oppelt P, Jackson R, Rich J, Paniello R, Zevallos J, Adkins D, Thorstad W
    Head Neck 2019 Mar;41(3):722-729
  • Risk and Rate of Occult Contralateral Nodal Disease in Surgically Treated Patients With Human Papillomavirus-Related Squamous Cell Carcinoma of the Base of the Tongue
    Last AS, Pipkorn P, Chen S, Kallogjeri D, Zenga J, Rich JT, Paniello R, Zevallos J, Chernock R, Adkins D, Oppelt P, Gay H, Daly M, Thorstad W, Jackson RS
    JAMA Otolaryngol Head Neck Surg 2019 Nov 7;146(1):50-56
  • Radiation Therapy Dose De-Escalation Compared to Standard Dose Radiation Therapy in Definitive Treatment of HPV-Positive Oropharyngeal Squamous Cell Carcinoma
    Gabani P, Lin AJ, Barnes J, Oppelt PJ, Adkins DR, Rich JT, Zevallos JP, Daly MD, Gay HA, Thorstad WL
    Radiother Oncol 2019 May;134:81-88
  • Prospective Assessment of the Clinical Benefit of a Tailored Cancer Gene Set Built on a Next-Generation Sequencing Platform in Patients With Recurrent or Metastatic Head and Neck Cancer
    Westbrook TC, Hagemann IS, Ley J, Chen K, Palka KT, Liu J, Chen L, Oppelt PJ, Adkins DR
    Med Oncol 2019 Dec 21;37(2):12
  • Nab-Paclitaxel-Based Induction Chemotherapy Followed by Cisplatin and Radiation Therapy for Human Papillomavirus-Unrelated Head and Neck Squamous-Cell Carcinoma
    Johnson KCC, Ley J, Oppelt PJ, Lu J, Gay HA, Daly M, Jackson R, Rich J, Pipkorn P, Paniello RC, Zevallos J, Thorstad W, Adkins DR
    Med Oncol 2019 Oct 8;36(11):93
  • Impact on Health-Related Quality of Life of Induction Chemotherapy Compared With Concurrent Cisplatin and Radiation Therapy in Patients With Head and Neck Cancer
    Adkins D, Ley J, Oppelt P, Gay HA, Daly M, Paniello RC, Jackson R, Pipkorn P, Rich J, Zevallos J, Trinkaus K, Thorstad W
    Clin Oncol (R Coll Radiol) 2019 Sep;31(9):e123-e131
  • Palbociclib and Cetuximab in Platinum-Resistant and in Cetuximab-Resistant Human Papillomavirus-Unrelated Head and Neck Cancer: A Multicentre, Multigroup, Phase 2 Trial
    Adkins DR, Ley J, Neupane P, Worden F, Sacco AG, Palka KT, Grilley-Olson JE, Maggiore R, Salama NN, Trinkaus K, Van Tine BA, Steuer CE, Saba NF, Oppelt PJ
    Lancet Oncol 2019 Sep;20(9):1295-1305
  • Eliminating Postoperative Radiation to the Pathologically Node-Negative Neck: Long-Term Results of a Prospective Phase II Study
    Contreras JA, Spencer C, DeWees T, Haughey B, Henke LE, Chin RI, Paniello R, Rich J, Jackson R, Oppelt P, Pipkorn P, Zevallos J, Chernock R, Nussenbaum B, Daly M, Gay H, Adkins D, Thorstad W
    J Clin Oncol 2019 Oct 1;37(28):2548-2555
  • Pretreatment Metabolic Tumor Volume as a Prognostic Factor in HPV-Associated Oropharyngeal Cancer in the Context of AJCC 8th Edition Staging
    Floberg JM, DeWees TA, Chin RI, Garsa AA, Dehdashti F, Nussenbaum B, Oppelt PJ, Adkins DR, Gay HA, Thorstad WL
    Head Neck 2018 Oct;40(10):2280-2287
  • Post-Operative Radiation Effects on Lymphopenia, Neutrophil to Lymphocyte Ratio, and Clinical Outcomes in Palatine Tonsil Cancers
    Lin AJ, Rao YJ, Chin RI, Campian J, Mullen D, Thotala D, Daly M, Gay H, Oppelt P, Hallahan D, Adkins D, Thorstad W
    Oral Oncol 2018 Nov;86:1-7
  • Pazopanib Plus Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: An Open-Label, Phase 1b and Expansion Study
    Adkins D, Mehan P, Ley J, Siegel MJ, Siegel BA, Dehdashti F, Jiang X, Salama NN, Trinkaus K, Oppelt P
    Lancet Oncol 2018 Aug;19(8):1082-1093
  • Induction Chemotherapy in the Treatment of Nasopharyngeal Carcinoma: Clinical Outcomes and Patterns of Care
    Gabani P, Barnes J, Lin AJ, Rudra S, Oppelt P, Adkins D, Rich JT, Zevallos JP, Daly MD, Gay HA, Thorstad WL
    Cancer Med 2018 Aug;7(8):3592-3603
  • Predictors of Acute Throat or Esophageal Patient Reported Pain During Radiation Therapy for Head and Neck Cancer
    Gay HA, Oh JH, Apte AP, Daly MD, Adkins DR, Rich J, Oppelt PJ, Dyk PT, Mullen DF, Eschen L, Chin RI, Nussenbaum B, Haughey BH, Thorstad WL, Deasy JO
    Clin Transl Radiat Oncol 2018 Sep 4;13:1-6
  • Clinical Benefit of Nanoparticle Albumin-Bound-Paclitaxel in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma Resistant to Cremophor-Based Paclitaxel or Docetaxel
    Ley J, Wildes TM, Daly K, Oppelt P, Adkins D
    Med Oncol 2017 Feb;34(2):28
  • Nab-Paclitaxel-Based Induction Chemotherapy With or Without Cetuximab for Locally Advanced Head and Neck Squamous Cell Carcinoma
    Adkins D, Ley J, Oppelt P, Wildes TM, Gay HA, Daly M, Rich J, Paniello RC, Jackson R, Pipkorn P, Nussenbaum B, Trinkaus K, Thorstad W
    Oral Oncol 2017 Sep;72:26-31
  • Gastrointestinal Stromal Tumors (GISTs): Point Mutations Matter in Management, a Review
    Oppelt PJ, Hirbe AC, Van Tine BA
    J Gastrointest Oncol 2017 Jun;8(3):466-473
  • Approach to Chemotherapy-Associated Thrombosis
    Oppelt P, Betbadal A, Nayak L
    Vasc Med 2015 Apr;20(2):153-61

Book Chapters

  • Cancer of the Head and Neck
    Oppelt P, Palka KT, Ley J, Adkins DR
    In: DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology Review, 5th Edition (Morgensztern D, Govindan R, Devarakonda S, Trikalinos NA, Editors), Wolters Kluwer, Philadelphia, 2022
  • Head and Neck Cancer
    Oppelt P, Palka KT, Daly MD, Pipkorn P, Ley J, Adkins D
    In: The Washington Manual of Oncology, 4th Edition (Morgensztern D, Ghobadi A, Govindan R, Editors), Wolters Kluwer, Philadelphia, 2022