Faculty
Oncology Division
Alphabetical list (active faculty):   
Katrina S. Pedersen

Katrina S. Pedersen, MD, MS

Assistant Professor

Department of Medicine

Oncology Division

Medical Oncology

Clinical Interests

  • Small bowel adenocarcinoma
  • Colorectal cancer
  • Appendiceal cancer
  • Pancreatic cancer
  • Gastrointestinal cancer

Contact

  • 314-362-9115 (office)
  • 314-362-7086 (fax)
  • Division of Oncology
    Mail Stop 8056-0029-11
    Washington University
    660 South Euclid Avenue
    St. Louis, MO 63110

Research

As a practitioner of medical oncology focusing in gastrointestinal cancers, I use my experience with patients to drive my clinical and translational research aims. I have previously trained as a basic scientist, studying molecular oncology and the epigenetic mechanisms of carcinogenesis, and have completed graduate coursework in advanced molecular biology, cancer biology, biochemistry, and free radical biology. I have applied that knowledge to examining leukocyte DNA methylation signatures in pancreas cancers for discovery of circulating diagnostic biomarkers. Turning to practices engaging Systems Biology, I have more recently analyzed RNA-Seq data of pancreas precursor lesions and tumors in search of transcriptome-wide expression-level stepwise changes leading to pancreatic carcinogenesis. I have funding for ongoing pilot studies utilizing genome-wide DNA mate pair analysis to develop predictive biomarkers of therapy in pancreatic cancer patients. A trial developed with my mentor, Dr. Robert McWilliams, will shortly be opening to study outcomes of pembrolizumab therapy in unselected patients with small bowel adenocarcinoma. I look forward to collaborating with the numerous talented and creative researchers at Washington University to improve outcomes for patients with gastrointestinal and hepatobiliary cancers.