Daniel A. Rauch, PhD

Assistant Professor
Department of Medicine
Oncology Division
Molecular Oncology

Research Interests

  • Viral oncogenes
  • Leukemia/lymphoma
  • Tumor immunity
  • Imaging


  • 314-747-0506 (office)
  • 314-362-8838 (lab)
  • 314-747-2797 (fax)
  • 562 McDonnell Medical Sciences Building (office)
  • 562 McDonnell Medical Sciences Building (lab)
  • Division of Oncology
    Campus Box 8069
    Washington University Medical School
    660 South Euclid Avenue
    St. Louis, MO 63110


  • Physician's Role in Coordinating Care of Hospitalized Children
    Rauch DA

    Pediatrics 2018 Aug;142(2)
  • An Activating Mutation of Interferon Regulatory Factor 4 (IRF4) in Adult T-Cell Leukemia
    Cherian MA, Olson S, Sundaramoorthi H, Cates K, Cheng X, Harding J, Martens A, Challen GA, Tyagi M, Ratner L, Rauch D
    J Biol Chem 2018 May 4;293(18):6844-6858
  • HTLV-1 Viral Oncogene HBZ Induces Osteolytic Bone Disease in Transgenic Mice
    Esser AK, Rauch DA, Xiang J, Harding JC, Kohart NA, Ross MH, Su X, Wu K, Huey D, Xu Y, Vij K, Green PL, Rosol TJ, Niewiesk S, Ratner L, Weilbaecher KN
    Oncotarget 2017 Aug 27;8(41):69250-69263
  • Dose-Adjusted EPOCH Chemotherapy With Bortezomib and Raltegravir for Human T-Cell Leukemia Virus-Associated Adult T-Cell Leukemia Lymphoma
    Ratner L, Rauch D, Abel H, Caruso B, Noy A, Barta SK, Parekh S, Ramos JC, Ambinder R, Phillips A, Harding J, Baydoun HH, Cheng X, Jacobson S
    Blood Cancer J 2016 Mar 25;6:e408
  • Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-KappaB Inhibitor A20 and Constitutive NF-KappaB Signaling
    Pujari R, Hunte R, Thomas R, van der Weyden L, Rauch D, Ratner L, Nyborg JK, Ramos JC, Takai Y, Shembade N
    PLoS Pathog 2015 Mar 16;11(3):e1004721
  • IL-15 Deficient Tax Mice Reveal a Role for IL-1alpha in Tumor Immunity
    Rauch DA, Harding JC, Ratner L
    PLoS One 2014 Jan 8;9(1):e85028
  • Targeting HTLV-1 Activation of NFkappaB in Mouse Models and ATLL Patients
    Rauch DA, Ratner L
    Viruses 2011 Jun;3(6):886-900
  • The ARF Tumor Suppressor Regulates Bone Remodeling and Osteosarcoma Development in Mice
    Rauch DA, Hurchla MA, Harding JC, Deng H, Shea LK, Eagleton MC, Niewiesk S, Lairmore MD, Piwnica-Worms D, Rosol TJ, Weber JD, Ratner L, Weilbaecher KN
    PLoS One 2010 Dec 30;5(12):e15755
  • T-Cell Activation Promotes Tumorigenesis in Inflammation-Associated Cancer
    Rauch D, Gross S, Harding J, Bokhari S, Niewiesk S, Lairmore M, Piwnica-Worms D, Ratner L
    Retrovirology 2009 Dec 17;6:116
  • Bioluminescence Imaging of Myeloperoxidase Activity in Vivo
    Gross S, Gammon ST, Moss BL, Rauch D, Harding J, Heinecke JW, Ratner L, Piwnica-Worms D
    Nat Med 2009 Apr;15(4):455-61
  • Imaging Spontaneous Tumorigenesis: Inflammation Precedes Development of Peripheral NK Tumors
    Rauch D, Gross S, Harding J, Niewiesk S, Lairmore M, Piwnica-Worms D, Ratner L
    Blood 2009 Feb 12;113(7):1493-500
  • Cholesterol Dependence of HTLV-I Infection
    Wielgosz MM, Rauch DA, Jones KS, Ruscetti FW, Ratner L
    AIDS Res Hum Retroviruses 2005 Jan;21(1):43-50
  • Herpes Simplex Virus With Highly Reduced GD Levels Can Efficiently Enter and Spread Between Human Keratinocytes
    Huber MT, Wisner TW, Hegde NR, Goldsmith KA, Rauch DA, Roller RJ, Krummenacher C, Eisenberg RJ, Cohen GH, Johnson DC
    J Virol 2001 Nov;75(21):10309-18
  • Mutations in Herpes Simplex Virus Glycoprotein D Distinguish Entry of Free Virus From Cell-Cell Spread
    Rauch DA, Rodriguez N, Roller RJ
    J Virol 2000 Dec;74(24):11437-46
  • Herpesvirus Entry Mediator HVEM Mediates Cell-Cell Spread in BHK(TK-) Cell Clones
    Roller RJ, Rauch D
    J Virol 1998 Feb;72(2):1411-7
  • The Exon Splicing Silencer in Human Immunodeficiency Virus Type 1 Tat Exon 3 Is Bipartite and Acts Early in Spliceosome Assembly
    Si ZH, Rauch D, Stoltzfus CM
    Mol Cell Biol 1998 Sep;18(9):5404-13