Oncology Division

Katherine N. Weilbaecher, MD

Department of Medicine
Oncology Division
Molecular Oncology
Department of Cell Biology & Physiology
Department of Pathology & Immunology

Clinical Interests

  • Breast cancer
  • Bone metastasis

Research Interests

  • Skeletal metastasis
  • Beta 3 integrin
  • Osteoclast/macrophage biology
  • HTLV-1
  • Targeted nanotherapy


  • 314-454-8858 (tel)
  • 314-454-7086 (fax)
  • Room 806, McDonnell Sciences Building (office)
  • Washington University School of Medicine
    Division of Oncology
    Campus Box 8069
    660 South Euclid Avenue
    St. Louis, MO 63110

Original Research Articles

  • Assessing the Effectiveness of the National Comprehensive Cancer Network Genetic Testing Guidelines in Identifying African American Breast Cancer Patients With Deleterious Genetic Mutations
    Ademuyiwa FO, Salyer P, Ma Y, Fisher S, Colditz G, Weilbaecher KN, Bierut LJ
    Breast Cancer Res Treat 2019 Jul 19; [Epub ahead of print]
  • Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation
    Heo GS, Zhao Y, Sultan D, Zhang X, Detering L, Luehmann HP, Zhang X, Li R, Choksi A, Sharp S, Levingston S, Primeau T, Reichert DE, Sun G, Razani B, Li S, Weilbaecher KN, Dehdashti F, Wooley KL, Liu Y
    ACS Appl Mater Interfaces 2019 Jun 5;11(22):19669-19678
  • Retrospective Analysis of Treatment Patterns and Effectiveness of Palbociclib and Subsequent Regimens in Metastatic Breast Cancer
    Xi J, Oza A, Thomas S, Ademuyiwa F, Weilbaecher K, Suresh R, Bose R, Cherian M, Hernandez-Aya L, Frith A, Peterson L, Luo J, Krishnamurthy J, Ma CX
    J Natl Compr Canc Netw 2019 Feb;17(2):141-147
  • Circulating Receptor Activator of Nuclear Factor-KappaB (RANK), RANK Ligand (RANKL), and Mammographic Density in Premenopausal Women
    Toriola AT, Appleton CM, Zong X, Luo J, Weilbaecher K, Tamimi RM, Colditz GA
    Cancer Prev Res (Phila) 2018 Dec;11(12):789-796
  • Inhibition of the Stromal P38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss
    Murali B, Ren Q, Luo X, Faget DV, Wang C, Johnson RM, Gruosso T, Flanagan KC, Fu Y, Leahy K, Alspach E, Su X, Ross MH, Burnette B, Weilbaecher KN, Park M, Mbalaviele G, Monahan JB, Stewart SA
    Cancer Res 2018 Oct 1;78(19):5618-5630
  • The Beta3-Integrin Endothelial Adhesome Regulates Microtubule-Dependent Cell Migration
    Atkinson SJ, Gontarczyk AM, Alghamdi AA, Ellison TS, Johnson RT, Fowler WJ, Kirkup BM, Silva BC, Harry BE, Schneider JG, Weilbaecher KN, Mogensen MM, Bass MD, Parsons M, Edwards DR, Robinson SD
    EMBO Rep 2018 Jul;19(7)
  • Balixafortide Plus Eribulin in HER2-Negative Metastatic Breast Cancer: A Phase 1, Single-Arm, Dose-Escalation Trial
    Pernas S, Martin M, Kaufman PA, Gil-Martin M, Gomez Pardo P, Lopez-Tarruella S, Manso L, Ciruelos E, Perez-Fidalgo JA, Hernando C, Ademuyiwa FO, Weilbaecher K, Mayer I, Pluard TJ, Martinez Garcia M, Vahdat L, Perez-Garcia J, Wach A, Barker D, Fung S, Romagnoli B, Cortes J
    Lancet Oncol 2018 Jun;19(6):812-824
  • Perfusion-Based Fluorescence Imaging Method Delineates Diverse Organs and Identifies Multifocal Tumors Using Generic Near-Infrared Molecular Probes
    Miller J, Wang ST, Orukari I, Prior J, Sudlow G, Su X, Liang K, Tang R, Hillman EMC, Weilbaecher KN, Culver JP, Berezin MY, Achilefu S
    J Biophotonics 2018 Apr;11(4):e201700232
  • Breast and Pancreatic Cancer Interrupt IRF8-Dependent Dendritic Cell Development to Overcome Immune Surveillance
    Meyer MA, Baer JM, Knolhoff BL, Nywening TM, Panni RZ, Su X, Weilbaecher KN, Hawkins WG, Ma C, Fields RC, Linehan DC, Challen GA, Faccio R, Aft RL, DeNardo DG
    Nat Commun 2018 Mar 28;9(1):1250
  • Radionuclides Transform Chemotherapeutics Into Phototherapeutics for Precise Treatment of Disseminated Cancer
    Kotagiri N, Cooper ML, Rettig M, Egbulefu C, Prior J, Cui G, Karmakar P, Zhou M, Yang X, Sudlow G, Marsala L, Chanswangphuwana C, Lu L, Habimana-Griffin L, Shokeen M, Xu X, Weilbaecher K, Tomasson M, Lanza G, DiPersio JF, Achilefu S
    Nat Commun 2018 Jan 18;9(1):275
  • Bone-Induced Expression of Integrin Beta3 Enables Targeted Nanotherapy of Breast Cancer Metastases
    Ross MH, Esser AK, Fox GC, Schmieder AH, Yang X, Hu G, Pan D, Su X, Xu Y, Novack DV, Walsh T, Colditz GA, Lukaszewicz GH, Cordell E, Novack J, Fitzpatrick JAJ, Waning DL, Mohammad KS, Guise TA, Lanza GM, Weilbaecher KN
    Cancer Res 2017 Nov 15;77(22):6299-6312
  • HTLV-1 Viral Oncogene HBZ Induces Osteolytic Bone Disease in Transgenic Mice
    Esser AK, Rauch DA, Xiang J, Harding JC, Kohart NA, Ross MH, Su X, Wu K, Huey D, Xu Y, Vij K, Green PL, Rosol TJ, Niewiesk S, Ratner L, Weilbaecher KN
    Oncotarget 2017 Aug 27;8(41):69250-69263
  • Differences in the Mutational Landscape of Triple-Negative Breast Cancer in African Americans and Caucasians
    Ademuyiwa FO, Tao Y, Luo J, Weilbaecher K, Ma CX
    Breast Cancer Res Treat 2017 Feb;161(3):491-499
  • Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma
    Fontana F, Ge X, Su X, Hathi D, Xiang J, Cenci S, Civitelli R, Shoghi KI, Akers WJ, D'avignon A, Weilbaecher KN, Shokeen M
    Clin Cancer Res 2017 Jan 15;23(2):416-429
  • Antagonizing Integrin Beta3 Increases Immunosuppression in Cancer
    Su X, Esser AK, Amend SR, Xiang J, Xu Y, Ross MH, Fox GC, Kobayashi T, Steri V, Roomp K, Fontana F, Hurchla MA, Knolhoff BL, Meyer MA, Morgan EA, Tomasson JC, Novack JS, Zou W, Faccio R, Novack DV, Robinson SD, Teitelbaum SL, DeNardo DG, Schneider JG, Weilbaecher KN
    Cancer Res 2016 Jun 15;76(12):3484-95
  • Dickkopf-Related Protein 1 (Dkk1) Regulates the Accumulation and Function of Myeloid Derived Suppressor Cells in Cancer
    D'Amico L, Mahajan S, Capietto AH, Yang Z, Zamani A, Ricci B, Bumpass DB, Meyer M, Su X, Wang-Gillam A, Weilbaecher K, Stewart SA, DeNardo DG, Faccio R
    J Exp Med 2016 May 2;213(5):827-840
  • Effects of Neoadjuvant Chemotherapy With or Without Zoledronic Acid on Pathological Response: A Meta-Analysis of Randomised Trials
    Kroep JR, Charehbili A, Coleman RE, Aft RL, Hasegawa Y, Winter MC, Weilbaecher K, Akazawa K, Hinsley S, Putter H, Liefers GJ, Nortier JW, Kohno N
    Eur J Cancer 2016 Feb;54:57-63
  • Dual-Therapy With AlphavBeta3-Targeted Sn2 Lipase-Labile Fumagillin-Prodrug Nanoparticles and Zoledronic Acid in the Vx2 Rabbit Tumor Model
    Esser AK, Schmieder AH, Ross MH, Xiang J, Su X, Cui G, Zhang H, Yang X, Allen JS, Williams T, Wickline SA, Pan D, Lanza GM, Weilbaecher KN
    Nanomedicine 2016 Jan;12(1):201-11
  • Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development
    Luo X, Fu Y, Loza AJ, Murali B, Leahy KM, Ruhland MK, Gang M, Su X, Zamani A, Shi Y, Lavine KJ, Ornitz DM, Weilbaecher KN, Long F, Novack DV, Faccio R, Longmore GD, Stewart SA
    Cell Rep 2016 Jan 5;14(1):82-92
  • CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer
    Xiang J, Hurchla MA, Fontana F, Su X, Amend SR, Esser AK, Douglas GJ, Mudalagiriyappa C, Luker KE, Pluard T, Ademuyiwa FO, Romagnoli B, Tuffin G, Chevalier E, Luker GD, Bauer M, Zimmermann J, Aft RL, Dembowsky K, Weilbaecher KN
    Mol Cancer Ther 2015 Nov;14(11):2473-85
  • Suppression of Beta3-Integrin in Mice Triggers a Neuropilin-1-Dependent Change in Focal Adhesion Remodelling That Can Be Targeted to Block Pathological Angiogenesis
    Ellison TS, Atkinson SJ, Steri V, Kirkup BM, Preedy ME, Johnson RT, Ruhrberg C, Edwards DR, Schneider JG, Weilbaecher K, Robinson SD
    Dis Model Mech 2015 Sep 1;8(9):1105-1119
  • Small Molecule MYC Inhibitor Conjugated to Integrin-Targeted Nanoparticles Extends Survival in a Mouse Model of Disseminated Multiple Myeloma
    Soodgupta D, Pan D, Cui G, Senpan A, Yang X, Lu L, Weilbaecher KN, Prochownik EV, Lanza GM, Tomasson MH
    Mol Cancer Ther 2015 Jun;14(6):1286-94
  • Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types
    Amend SR, Wilson WC, Chu L, Lu L, Liu P, Serie D, Su X, Xu Y, Wang D, Gramolini A, Wen XY, O'Neal J, Hurchla M, Vachon CM, Colditz G, Vij R, Weilbaecher KN, Tomasson MH
    PLoS One 2015 May 28;10(5):e0127828
  • Comparative Effectiveness on Survival of Zoledronic Acid Versus Pamidronate in Multiple Myeloma
    Sanfilippo KM, Gage B, Luo S, Weilbaecher K, Tomasson M, Vij R, Colditz G, Carson K
    Leuk Lymphoma 2015 Mar;56(3):615-21
  • Real-Time Intravital Imaging Establishes Tumor-Associated Macrophages as the Extraskeletal Target of Bisphosphonate Action in Cancer
    Junankar S, Shay G, Jurczyluk J, Ali N, Down J, Pocock N, Parker A, Nguyen A, Sun S, Kashemirov B, McKenna CE, Croucher PI, Swarbrick A, Weilbaecher K, Phan TG, Rogers MJ
    Cancer Discov 2015 Jan;5(1):35-42
  • Thrombospondin-1 Regulates Bone Homeostasis Through Effects on Bone Matrix Integrity and Nitric Oxide Signaling in Osteoclasts
    Amend SR, Uluckan O, Hurchla M, Leib D, Novack DV, Silva M, Frazier W, Weilbaecher KN
    J Bone Miner Res 2015 Jan;30(1):106-15
  • Acute Depletion of Endothelial Beta3-Integrin Transiently Inhibits Tumor Growth and Angiogenesis in Mice
    Steri V, Ellison TS, Gontarczyk AM, Weilbaecher K, Schneider JG, Edwards D, Fruttiger M, Hodivala-Dilke KM, Robinson SD
    Circ Res 2014 Jan 3;114(1):79-91
  • A Randomized Phase II Trial Investigating the Effect of Platelet Function Inhibition on Circulating Tumor Cells in Patients With Metastatic Breast Cancer
    Roop RP, Naughton MJ, Van Poznak C, Schneider JG, Lammers PE, Pluard TJ, Johnson F, Eby CS, Weilbaecher KN
    Clin Breast Cancer 2013 Dec;13(6):409-15
  • Very Late Antigen-4 (Alpha(4)beta(1) Integrin) Targeted PET Imaging of Multiple Myeloma
    Soodgupta D, Hurchla MA, Jiang M, Zheleznyak A, Weilbaecher KN, Anderson CJ, Tomasson MH, Shokeen M
    PLoS One 2013;8(2):e55841
  • Role of WNT7B-Induced Noncanonical Pathway in Advanced Prostate Cancer
    Zheng D, Decker KF, Zhou T, Chen J, Qi Z, Jacobs K, Weilbaecher KN, Corey E, Long F, Jia L
    Mol Cancer Res 2013 May;11(5):482-93
  • Noncompetitive Modulation of the Proteasome by Imidazoline Scaffolds Overcomes Bortezomib Resistance and Delays MM Tumor Growth in Vivo
    Lansdell TA, Hurchla MA, Xiang J, Hovde S, Weilbaecher KN, Henry RW, Tepe JJ
    ACS Chem Biol 2013 Mar 15;8(3):578-587
  • Antagonism of Inhibitor of Apoptosis Proteins Increases Bone Metastasis Via Unexpected Osteoclast Activation
    Yang C, Davis JL, Zeng R, Vora P, Su X, Collins LI, Vangveravong S, Mach RH, Piwnica-Worms D, Weilbaecher KN, Faccio R, Novack DV
    Cancer Discov 2013 Feb;3(2):212-23
  • The Epoxyketone-Based Proteasome Inhibitors Carfilzomib and Orally Bioavailable Oprozomib Have Anti-Resorptive and Bone-Anabolic Activity in Addition to Anti-Myeloma Effects
    Hurchla MA, Garcia-Gomez A, Hornick MC, Ocio EM, Li A, Blanco JF, Collins L, Kirk CJ, Piwnica-Worms D, Vij R, Tomasson MH, Pandiella A, San Miguel JF, Garayoa M, Weilbaecher KN
    Leukemia 2013 Feb;27(2):430-40
  • The ADP Receptor P2RY12 Regulates Osteoclast Function and Pathologic Bone Remodeling
    Su X, Floyd DH, Hughes A, Xiang J, Schneider JG, Uluckan O, Heller E, Deng H, Zou W, Craft CS, Wu K, Hirbe AC, Grabowska D, Eagleton MC, Townsley S, Collins L, Piwnica-Worms D, Steinberg TH, Novack DV, Conley PB, Hurchla MA, Rogers M, Weilbaecher KN
    J Clin Invest 2012 Oct 1;122(10):3579-92
  • Integrin Alpha(V)beta(3) as a PET Imaging Biomarker for Osteoclast Number in Mouse Models of Negative and Positive Osteoclast Regulation
    Zheleznyak A, Wadas TJ, Sherman CD, Wilson JM, Kostenuik PJ, Weilbaecher KN, Anderson CJ
    Mol Imaging Biol 2012 Aug;14(4):500-8
  • Breast Cancer Cell Targeting by Prenylation Inhibitors Elucidated in Living Animals With a Bioluminescence Reporter
    Chinault SL, Prior JL, Kaltenbronn KM, Penly A, Weilbaecher KN, Piwnica-Worms D, Blumer KJ
    Clin Cancer Res 2012 Aug 1;18(15):4136-44
  • Effect of (Neo)adjuvant Zoledronic Acid on Disease-Free and Overall Survival in Clinical Stage II/III Breast Cancer
    Aft RL, Naughton M, Trinkaus K, Weilbaecher K
    Br J Cancer 2012 Jun 26;107(1):7-11
  • Hedgehog Signaling Inhibition Blocks Growth of Resistant Tumors Through Effects on Tumor Microenvironment
    Heller E, Hurchla MA, Xiang J, Su X, Chen S, Schneider J, Joeng KS, Vidal M, Goldberg L, Deng H, Hornick MC, Prior JL, Piwnica-Worms D, Long F, Cagan R, Weilbaecher KN
    Cancer Res 2012 Feb 15;72(4):897-907
  • CD8+ T Cells Regulate Bone Tumor Burden Independent of Osteoclast Resorption
    Zhang K, Kim S, Cremasco V, Hirbe AC, Novack DV, Weilbaecher K, Faccio R
    Cancer Res 2011 Jul 15;71(14):4799-808
  • The ARF Tumor Suppressor Regulates Bone Remodeling and Osteosarcoma Development in Mice
    Rauch DA, Hurchla MA, Harding JC, Deng H, Shea LK, Eagleton MC, Niewiesk S, Lairmore MD, Piwnica-Worms D, Rosol TJ, Weber JD, Ratner L, Weilbaecher KN
    PLoS One 2010 Dec 30;5(12):e15755
  • A Gene Expression Signature That Predicts the Therapeutic Response of the Basal-Like Breast Cancer to Neoadjuvant Chemotherapy
    Lin Y, Lin S, Watson M, Trinkaus KM, Kuo S, Naughton MJ, Weilbaecher K, Fleming TP, Aft RL
    Breast Cancer Res Treat 2010 Oct;123(3):691-699
  • A Role for the Epithelial Microenvironment at Tumor Boundaries: Evidence From Drosophila and Human Squamous Cell Carcinomas
    Vidal M, Salavaggione L, Ylagan L, Wilkins M, Watson M, Weilbaecher K, Cagan R
    Am J Pathol 2010 Jun;176(6):3007-14
  • Effect of Zoledronic Acid on Disseminated Tumour Cells in Women With Locally Advanced Breast Cancer: An Open Label, Randomised, Phase 2 Trial
    Aft R, Naughton M, Trinkaus K, Watson M, Ylagan L, Chavez-MacGregor M, Zhai J, Kuo S, Shannon W, Diemer K, Herrmann V, Dietz J, Ali A, Ellis M, Weiss P, Eberlein T, Ma C, Fracasso PM, Zoberi I, Taylor M, Gillanders W, Pluard T, Mortimer J, Weilbaecher K
    Lancet Oncol 2010 May;11(5):421-8
  • Dissection of Platelet and Myeloid Cell Defects by Conditional Targeting of the Beta3-Integrin Subunit
    Morgan EA, Schneider JG, Baroni TE, Uluckan O, Heller E, Hurchla MA, Deng H, Floyd D, Berdy A, Prior JL, Piwnica-Worms D, Teitelbaum SL, Ross FP, Weilbaecher KN
    FASEB J 2010 Apr;24(4):1117-27
  • Targeting the AlphavBeta3 Integrin for Small-Animal PET/CT of Osteolytic Bone Metastases
    Wadas TJ, Deng H, Sprague JE, Zheleznyak A, Weilbaecher KN, Anderson CJ
    J Nucl Med 2009 Nov;50(11):1873-80
  • The Bisphosphonate Zoledronic Acid Decreases Tumor Growth in Bone in Mice With Defective Osteoclasts
    Hirbe AC, Roelofs AJ, Floyd DH, Deng H, Becker SN, Lanigan LG, Apicelli AJ, Xu Z, Prior JL, Eagleton MC, Piwnica-Worms D, Rogers MJ, Weilbaecher K
    Bone 2009 May;44(5):908-16
  • CD47 Regulates Bone Mass and Tumor Metastasis to Bone
    Uluckan O, Becker SN, Deng H, Zou W, Prior JL, Piwnica-Worms D, Frazier WA, Weilbaecher KN
    Cancer Res 2009 Apr 1;69(7):3196-204
  • Interferon-{gamma} Targets Cancer Cells and Osteoclasts to Prevent Tumor-Associated Bone Loss and Bone Metastases
    Xu Z, Hurchla MA, Deng H, Uluckan O, Bu F, Berdy A, Eagleton MC, Heller EA, Floyd DH, Dirksen WP, Shu S, Tanaka Y, Fernandez SA, Rosol TJ, Weilbaecher KN
    J Biol Chem 2009 Feb 13;284(7):4658-66
  • Multiple Facets of JunD Gene Expression Are Atypical Among AP-1 Family Members
    Hernandez JM, Floyd DH, Weilbaecher KN, Green PL, Boris-Lawrie K
    Oncogene 2008 Aug 14;27(35):4757-67
  • APT102, a Novel Adpase, Cooperates With Aspirin to Disrupt Bone Metastasis in Mice
    Uluckan O, Eagleton MC, Floyd DH, Morgan EA, Hirbe AC, Kramer M, Dowland N, Prior JL, Piwnica-Worms D, Jeong SS, Chen R, Weilbaecher K
    J Cell Biochem 2008 Jul 1;104(4):1311-1323
  • RelB Is the NF-KappaB Subunit Downstream of NIK Responsible for Osteoclast Differentiation
    Vaira S, Johnson T, Hirbe AC, Alhawagri M, Anwisye I, Sammut B, O'Neal J, Zou W, Weilbaecher KN, Faccio R, Novack DV
    Proc Natl Acad Sci U S A 2008 Mar 11;105(10):3897-902
  • A Non-Tumor Suppressor Role for Basal p19ARF in Maintaining Nucleolar Structure and Function
    Apicelli AJ, Maggi LB Jr, Hirbe AC, Miceli AP, Olanich ME, Schulte-Winkeler CL, Saporita AJ, Kuchenreuther M, Sanchez J, Weilbaecher K, Weber JD
    Mol Cell Biol 2008 Feb;28(3):1068-80
  • Isolation and Molecular Profiling of Bone Marrow Micrometastases Identifies TWIST1 as a Marker of Early Tumor Relapse in Breast Cancer Patients
    Watson MA, Ylagan LR, Trinkaus KM, Gillanders WE, Naughton MJ, Weilbaecher KN, Fleming TP, Aft RL
    Clin Cancer Res 2007 Sep 1;13(17):5001-9
  • Disruption of CXCR4 Enhances Osteoclastogenesis and Tumor Growth in Bone
    Hirbe AC, Rubin J, Uluckan O, Morgan EA, Eagleton MC, Prior JL, Piwnica-Worms D, Weilbaecher KN
    Proc Natl Acad Sci U S A 2007 Aug 28;104(35):14062-7
  • Granulocyte Colony-Stimulating Factor Enhances Bone Tumor Growth in Mice in an Osteoclast-Dependent Manner
    Hirbe AC, Uluckan O, Morgan EA, Eagleton MC, Prior JL, Piwnica-Worms D, Trinkaus K, Apicelli A, Weilbaecher K
    Blood 2007 Apr 15;109(8):3424-31
  • Noninvasive Imaging of Osteoclasts in Parathyroid Hormone-Induced Osteolysis Using a 64Cu-Labeled RGD Peptide
    Sprague JE, Kitaura H, Zou W, Ye Y, Achilefu S, Weilbaecher KN, Teitelbaum SL, Anderson CJ
    J Nucl Med 2007 Feb;48(2):311-8
  • MRI Detection of Early Bone Metastases in B16 Mouse Melanoma Models
    Gauvain KM, Garbow JR, Song SK, Hirbe AC, Weilbaecher K
    Clin Exp Metastasis 2005 Sep;22(5):403-411
  • HTLV-1 Tax Transgenic Mice Develop Spontaneous Osteolytic Bone Metastases Prevented by Osteoclast Inhibition
    Gao L, Deng H, Zhao H, Hirbe A, Harding J, Ratner L, Weilbaecher K
    Blood 2005 Dec 15;106(13):4294-302
  • Platelet and Osteoclast Beta3 Integrins Are Critical for Bone Metastasis
    Bakewell SJ, Nestor P, Prasad S, Tomasson MH, Dowland N, Mehrotra M, Scarborough R, Kanter J, Abe K, Phillips D, Weilbaecher KN
    Proc Natl Acad Sci U S A 2003 Nov 25;100(24):14205-10
  • Comparison of Five Antibodies as Markers in the Diagnosis of Melanoma in Cytologic Preparations
    Sheffield MV, Yee H, Dorvault CC, Weilbaecher KN, Eltoum IA, Siegal GP, Fisher DE, Chhieng DC
    Am J Clin Pathol 2002 Dec;118(6):930-6
  • The Melanocyte-Specific Isoform of the Microphthalmia Transcription Factor Affects the Phenotype of Human Melanoma
    Selzer E, Wacheck V, Lucas T, Heere-Ress E, Wu M, Weilbaecher KN, Schlegel W, Valent P, Wrba F, Pehamberger H, Fisher D, Jansen B
    Cancer Res 2002 Apr 1;62(7):2098-103
  • Role for Microphthalmia Transcription Factor in the Diagnosis of Metastatic Malignant Melanoma
    Granter SR, Weilbaecher KN, Quigley C, Fisher DE
    Appl Immunohistochem Mol Morphol 2002 Mar;10(1):47-51
  • Microphthalmia Transcription Factor: A Sensitive and Specific Marker for Malignant Melanoma in Cytologic Specimens
    Dorvault CC, Weilbaecher KN, Yee H, Fisher DE, Chiriboga LA, Xu Y, Chhieng DC
    Cancer 2001 Oct 25;93(5):337-43
  • Linkage of M-CSF Signaling to Mitf, TFE3, and the Osteoclast Defect in Mitf(Mi/Mi) Mice
    Weilbaecher KN, Motyckova G, Huber WE, Takemoto CM, Hemesath TJ, Xu Y, Hershey CL, Dowland NR, Wells AG, Fisher DE
    Mol Cell 2001 Oct;8(4):749-58
  • Microphthalmia Transcription Factor: Not a Sensitive or Specific Marker for the Diagnosis of Desmoplastic Melanoma and Spindle Cell (Non-Desmoplastic) Melanoma
    Granter SR, Weilbaecher KN, Quigley C, Fletcher CD, Fisher DE
    Am J Dermatopathol 2001 Jun;23(3):185-9
  • Linking Osteopetrosis and Pycnodysostosis: Regulation of Cathepsin K Expression by the Microphthalmia Transcription Factor Family
    Motyckova G, Weilbaecher KN, Horstmann M, Rieman DJ, Fisher DZ, Fisher DE
    Proc Natl Acad Sci U S A 2001 May 8;98(10):5798-803
  • Clear Cell Sarcoma Shows Immunoreactivity for Microphthalmia Transcription Factor: Further Evidence for Melanocytic Differentiation
    Granter SR, Weilbaecher KN, Quigley C, Fletcher CD, Fisher DE
    Mod Pathol 2001 Jan;14(1):6-9
  • Microphthalmia Transcription Factor Expression in Cutaneous Benign, Malignant Melanocytic, and Nonmelanocytic Tumors
    King R, Googe PB, Weilbaecher KN, Mihm MC Jr, Fisher DE
    Am J Surg Pathol 2001 Jan;25(1):51-7
  • Microphthalmia Transcription Factor. A Sensitive and Specific Melanocyte Marker for Melanoma Diagnosis
    King R, Weilbaecher KN, McGill G, Cooley E, Mihm M, Fisher DE
    Am J Pathol 1999 Sep;155(3):731-8
  • Alpha-Melanocyte-Stimulating Hormone Signaling Regulates Expression of Microphthalmia, a Gene Deficient in Waardenburg Syndrome
    Price ER, Horstmann MA, Wells AG, Weilbaecher KN, Takemoto CM, Landis MW, Fisher DE
    J Biol Chem 1998 Dec 4;273(49):33042-7
  • Age-Resolving Osteopetrosis: A Rat Model Implicating Microphthalmia and the Related Transcription Factor TFE3
    Weilbaecher KN, Hershey CL, Takemoto CM, Horstmann MA, Hemesath TJ, Tashjian AH, Fisher DE
    J Exp Med 1998 Mar 2;187(5):775-85
  • Porphyria Cutanea Tarda and Hepatitis C Virus Infection in a Patient With Acute Liver Failure
    Jasmer RM, Larson MS, Weilbaecher KN
    West J Med 1994 Nov;161(5):513-5
  • Culture of Phenotypically Defined Hematopoietic Stem Cells and Other Progenitors at Limiting Dilution on Dexter Monolayers
    Weilbaecher K, Weissman I, Blume K, Heimfeld S
    Blood 1991 Aug 15;78(4):945-52
  • Long-Term Human Hematopoiesis in the SCID-Hu Mouse
    Namikawa R, Weilbaecher KN, Kaneshima H, Yee EJ, McCune JM
    J Exp Med 1990 Oct 1;172(4):1055-63
  • Lineage Specificity of Rearrangement and Expression of Genes Encoding the T Cell Receptor-T3 Complex and Immunoglobulin Heavy Chain in Leukemia
    Furley AJ, Chan LC, Mizutani S, Ford AM, Weilbaecher K, Pegram SM, Greaves MF
    Leukemia 1987 Sep;1(9):644-52
  • Developmentally Regulated Rearrangement and Expression of Genes Encoding the T Cell Receptor-T3 Complex
    Furley AJ, Mizutani S, Weilbaecher K, Dhaliwal HS, Ford AM, Chan LC, Molgaard HV, Toyonaga B, Mak T, van den Elsen P, et al.
    Cell 1986 Jul 4;46(1):75-87