Patrick M. Grierson, MD, PhD

Senior Fellow
Began fellowship in 2016
Co-Chief Fellow (July 2017 - June 2019)

Clinical Focus

  • Solid tumor oncology

Research Focus

  • Solid tumor oncology

Type of Research

  • Solid tumor oncology


BS, University of Wisconsin, Madison, WI
MD, The Ohio State University College of Medicine, Columbus, OH
PhD, The Ohio State University, Columbus, OH
Post-graduate training
Residency, Barnes-Jewish Hospital, St. Louis, MO


  • IRAK4 Mediates Colitis-Induced Tumorigenesis and Chemoresistance in Colorectal Cancer
    Li Q, Chen Y, Zhang D, Grossman J, Li L, Khurana N, Jiang H, Grierson PM, Herndon J, DeNardo DG, Challen GA, Liu J, Ruzinova MB, Fields RC, Lim KH
    JCI Insight 2019 Oct 3;4(19)
  • Phase Ib/II Study Combining Tosedostat With Capecitabine in Patients With Advanced Pancreatic Adenocarcinoma
    Grierson P, Teague A, Suresh R, Lim K-H, Amin M, Pedersen K, Tan B, Huffman J, Boice N, Du L, Liu J, Lockhart AC, Wang-Gillam A
    Journal of Gastrointestinal Oncology, in press
  • Hepatocellular Carcinoma: Where Are We in 2018?
    Chapman WC, Korenblat KM, Fowler KJ, Saad N, Khan AS, Subramanian V, Doyle MBM, Dageforde LA, Tan B, Grierson P, Lin Y, Xu M, Brunt EM
    Curr Probl Surg 2018 Nov;55(11):450-503
  • Concurrent HER or PI3K Inhibition Potentiates the Antitumor Effect of the ERK Inhibitor Ulixertinib in Preclinical Pancreatic Cancer Models
    Jiang H, Xu M, Li L, Grierson P, Dodhiawala P, Highkin M, Zhang D, Li Q, Wang-Gillam A, Lim KH
    Mol Cancer Ther 2018 Oct;17(10):2144-2155
  • Distinct Clinical and Magnetic Resonance Features of Metastatic Hepatocellular Carcinoma Treated With Pembrolizumab: A Case Report of Late Response After Pseudoprogression
    Grierson P, Crites D, Ruzinova MB, Yano M, Lim KH
    Hepatol Commun 2017 Dec 19;2(2):148-151
  • Rapid Clinical and Radiographic Response With Combined Dabrafenib and Trametinib in Adults With BRAF-Mutated High-Grade Glioma
    Johanns TM, Ferguson CJ, Grierson PM, Dahiya S, Ansstas G
    J Natl Compr Canc Netw 2018 Jan;16(1):4-10
  • Immunotherapy in Gastrointestinal Cancers
    Grierson P, Lim KH, Amin M
    J Gastrointest Oncol 2017 Jun;8(3):474-484
  • Regulation of BLM Nucleolar Localization
    Tangeman L, McIlhatton MA, Grierson P, Groden J, Acharya S
    Genes (Basel) 2016 Sep 21;7(9)
  • Collaborating Functions of BLM and DNA Topoisomerase I in Regulating Human RDNA Transcription
    Grierson PM, Acharya S, Groden J
    Mutat Res 2013 Mar-Apr;743-744:89-96
  • BLM Helicase Facilitates RNA Polymerase I-Mediated Ribosomal RNA Transcription
    Grierson PM, Lillard K, Behbehani GK, Combs KA, Bhattacharyya S, Acharya S, Groden J
    Hum Mol Genet 2012 Mar 1;21(5):1172-83
  • Chromosome Breakage Is Regulated by the Interaction of the BLM Helicase and Topoisomerase IIalpha
    Russell B, Bhattacharyya S, Keirsey J, Sandy A, Grierson P, Perchiniak E, Kavecansky J, Acharya S, Groden J
    Cancer Res 2011 Jan 15;71(2):561-71

Book chapters

  • Approach to a Prolonged Prothrombin Time/Partial Thromboplastin Time
    Grierson PM, Battle NC
    In: The Washington Manual, General Internal Medicine Consult (Ciesielski TM, editor), 2017