Miriam T. Jacobs

Miriam T. Jacobs, MD

Senior Fellow

Began fellowship in 2017


BA, Wesleyan University, Middletown, CT
MD, Ben-Gurion University of the Negev Faculty of Health Sciences, Israel
Post-graduate training
Residency, University of California San Diego, San Diego, CA


  • Systemic IL-15 Promotes Allogeneic Cell Rejection in Patients Treated With Natural Killer Cell Adoptive Therapy
    Berrien-Elliott MM, Becker-Hapak M, Cashen AF, Jacobs M, Wong P, Foster M, McClain E, Desai S, Pence P, Cooley S, Brunstein C, Gao F, Abboud CN, Uy GL, Westervelt P, Jacoby MA, Pusic I, Stockerl-Goldstein KE, Schroeder MA, DiPersio JF, Soon-Shiong P, Miller JS, Fehniger TA
    Blood 2022 Feb 24;139(8):1177-1183
  • Hematopoietic Cell Transplantation Donor-Derived Memory-Like NK Cells Functionally Persist After Transfer Into Patients With Leukemia
    Berrien-Elliott MM, Foltz JA, Russler-Germain DA, Neal CC, Tran J, Gang M, Wong P, Fisk B, Cubitt CC, Marin ND, Zhou AY, Jacobs MT, Foster M, Schappe T, McClain E, Kersting-Schadek S, Desai S, Pence P, Becker-Hapak M, Eisele J, Mosior M, Marsala L, Griffith OL, Griffith M, Khan SM, Spencer DH, DiPersio JF, Romee R, Uy GL, Abboud CN, Ghobadi A, Westervelt P, Stockerl-Goldstein K, Schroeder MA, Wan F, Lie WR, Soon-Shiong P, Petti AA, Cashen AF, Fehniger TA
    Sci Transl Med 2022 Feb 23;14(633):eabm1375
  • Memory-Like Differentiation Enhances NK Cell Responses to Melanoma
    Marin ND, Krasnick BA, Becker-Hapak M, Conant L, Goedegebuure SP, Berrien-Elliott MM, Robbins KJ, Foltz JA, Foster M, Wong P, Cubitt CC, Tran J, Wetzel CB, Jacobs M, Zhou AY, Russler-Germain D, Marsala L, Schappe T, Fields RC, Fehniger TA
    Clin Cancer Res 2021 Sep 1;27(17):4859-4869
  • CD7-Deleted Hematopoietic Stem Cells Can Restore Immunity After CAR T Cell Therapy
    Kim MY, Cooper ML, Jacobs MT, Ritchey JK, Hollaway J, Fehniger TA, DiPersio JF
    JCI Insight 2021 Aug 23;6(16):e149819
  • Outcomes of Patients With Large B-Cell Lymphoma Progressing After Axicabtagene Ciloleucel Therapy
    Spiegel JY, Dahiya S, Jain MD, Tamaresis J, Nastoupil LJ, Jacobs MT, Ghobadi A, Lin Y, Lunning M, Lekakis L, Reagan P, Oluwole O, McGuirk J, Deol A, Goy A, Vu K, Andreadis C, Munoz J, Bennani NN, Vose JM, Dorritie KA, Neelapu SS, Locke FL, Rapoport AP, Hill BT, Miklos DB
    Blood 2021 Apr 1;137(13):1832-1835
  • The Use of Ruxolitinib for Acute Graft-Versus-Host Disease Developing After Solid Organ Transplantation
    Jacobs MT, Olson M, Ferreira BP, Jin RU, Hachem R, Byers D, Witt C, Ghobadi A, DiPersio JF, Pusic I
    Am J Transplant 2020 Feb;20(2):589-592
  • Genomic Landscape of Appendiceal Neoplasms
    Ang CS, Shen JP, Hardy-Abeloos CJ, Huang JK, Ross JS, Miller VA, Jacobs MT, Chen IL, Xu D, Ali SM, Baumgartner J, Lowy A, Fanta P, Ideker T, Millis SZ, Harismendy O
    JCO Precis Oncol 2018 Aug 8;2
  • Use of Low-Frequency Driver Mutations Detected by Cell-Free Circulating Tumor DNA to Guide Targeted Therapy in Non–Small-Cell Lung Cancer: A Multicenter Case Series
    Jacobs MT, Mohindra NA, Shantzer L, Chen IL, Phull H, Mitchell W, Raymond VM, Banks KC, Nagy RJ, Lanman RB, Christensen J, Patel JD, Clarke J, Patel SP
    JCO Precision Oncology 2018;2:1-10
  • Does Chemoselection Open the Door for Immunotherapy?
    Jacobs MT, Ruiz AL, Cohen EE
    Ann Oncol 2017 May 25; [Epub ahead of print]
  • The Use of Colchicine in Respiratory Diseases
    Benhamou OM, Geva S, Jacobs MT, Drew J, Waldman M, Kalchiem-Dekel O
    Current Respiratory Medicine Reviews 2013 Oct; 9(5):300-4
  • The Use of Interferons in Respiratory Diseases
    Benhamou OM, Jacobs MT, Drew J, Geva S, Waldman M, Kalchiem-Dekel O
    Current Respiratory Medicine Reviews 2013 Oct; 9(5):318-22
  • The Use of Methotrexate in Respiratory Diseases
    Jacobs MT, Waldman M, Day A, Kalchiem-Dekel O
    Current Respiratory Medicine Reviews 2013 Oct; 9(5):305-14
  • A Conserved Asparagine Residue in Transmembrane Segment 1 (TM1) of Serotonin Transporter Dictates Chloride-Coupled Neurotransmitter Transport
    Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E, Rudnick G, Noskov SY, DeFelice LJ, Meiler J, Blakely RD
    J Biol Chem 2011 Sep 2;286(35):30823-36
  • Mechanism for Alternating Access in Neurotransmitter Transporters
    Forrest LR, Zhang YW, Jacobs MT, Gesmonde J, Xie L, Honig BH, Rudnick G
    Proc Natl Acad Sci U S A 2008 Jul 29;105(30):10338-43
  • Ibogaine, a Noncompetitive Inhibitor of Serotonin Transport, Acts by Stabilizing the Cytoplasm-Facing State of the Transporter
    Jacobs MT, Zhang YW, Campbell SD, Rudnick G
    J Biol Chem 2007 Oct 5;282(40):29441-7